ZFX (zinc finger protein X-linked) - Rat Genome Database

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Gene: ZFX (zinc finger protein X-linked) Chlorocebus sabaeus
Analyze
Symbol: ZFX (Ensembl: ZFY)
Name: zinc finger protein X-linked (Ensembl:zinc finger protein Y-linked)
RGD ID: 18480524
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN fertilization (ortholog); germ cell development (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN chromatin (ortholog); nucleolus (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103232895; LOC103247451; uncharacterized LOC103232895; uncharacterized protein LOC103232895; zinc finger X-chromosomal protein-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X22,626,683 - 22,630,119 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblY99,000 - 128,638 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605624,506,189 - 24,574,127 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZFX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X22,626,683 - 22,630,119 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblY99,000 - 128,638 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605624,506,189 - 24,574,127 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ZFX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X24,148,982 - 24,216,255 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX24,149,173 - 24,216,255 (+)EnsemblGRCh38hg38GRCh38
GRCh37X24,167,099 - 24,234,372 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X24,077,824 - 24,142,549 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X23,929,464 - 23,989,474NCBI
CeleraX28,291,063 - 28,357,675 (+)NCBICelera
Cytogenetic MapXp22.11NCBI
HuRefX21,911,587 - 21,977,093 (+)NCBIHuRef
CHM1_1X24,199,109 - 24,265,719 (+)NCBICHM1_1
T2T-CHM13v2.0X23,733,193 - 23,800,453 (+)NCBIT2T-CHM13v2.0
Zfx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X93,118,237 - 93,194,250 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX93,118,237 - 93,167,308 (-)EnsemblGRCm39 Ensembl
GRCm38X94,074,631 - 94,150,645 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX94,074,631 - 94,123,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X91,319,970 - 91,368,746 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X90,327,351 - 90,375,619 (-)NCBIMGSCv36mm8
CeleraX80,975,763 - 81,039,081 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX41.48NCBI
Zfx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X62,798,483 - 62,847,068 (-)NCBIGRCr8
mRatBN7.2X58,804,690 - 58,853,155 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX58,804,691 - 58,853,265 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX60,242,347 - 60,291,471 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X63,743,468 - 63,792,591 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X61,294,490 - 61,343,654 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X63,158,368 - 63,204,971 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX63,158,976 - 63,204,530 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X63,749,779 - 63,797,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X81,430,210 - 81,477,028 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX59,240,896 - 59,287,404 (-)NCBICelera
Cytogenetic MapXq22NCBI
Zfx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555094,505,235 - 4,571,513 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555094,545,468 - 4,571,513 (+)NCBIChiLan1.0ChiLan1.0
ZFX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X25,945,055 - 26,015,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X25,950,870 - 26,018,681 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X16,745,872 - 16,813,486 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X24,118,870 - 24,183,804 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX24,118,956 - 24,183,804 (+)Ensemblpanpan1.1panPan2
ZFX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X19,722,172 - 19,793,059 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX19,760,045 - 19,790,196 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X19,654,055 - 19,750,307 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX19,691,983 - 19,750,306 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X19,692,562 - 19,787,144 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X19,726,301 - 19,820,841 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X19,782,461 - 19,877,301 (+)NCBIUU_Cfam_GSD_1.0
Zfx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X12,680,909 - 12,740,663 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936624416,753 - 472,030 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936624417,164 - 471,638 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX20,220,853 - 20,275,185 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X20,220,812 - 20,273,689 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X21,713,386 - 21,749,342 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Zfx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624897503,399 - 551,579 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624897503,741 - 550,027 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_037986415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000016420   ⟹   ENSCSAP00000014333
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblY99,000 - 128,638 (+)Ensembl
RefSeq Acc Id: XM_037986415   ⟹   XP_037842343
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,558 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986416   ⟹   XP_037842344
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,507,527 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986417   ⟹   XP_037842345
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,558 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986418   ⟹   XP_037842346
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,507,527 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986419   ⟹   XP_037842347
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,557 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986420   ⟹   XP_037842348
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,557 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986421   ⟹   XP_037842349
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,333 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986422   ⟹   XP_037842350
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,516,893 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986424   ⟹   XP_037842352
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,566 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986425   ⟹   XP_037842353
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,507,530 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986426   ⟹   XP_037842354
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,566 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986427   ⟹   XP_037842355
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,566 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986428   ⟹   XP_037842356
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,527,065 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986429   ⟹   XP_037842357
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,189 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986430   ⟹   XP_037842358
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,516,893 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986431   ⟹   XP_037842359
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,565 - 24,574,127 (+)NCBI
RefSeq Acc Id: XM_037986432   ⟹   XP_037842360
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605624,506,565 - 24,574,127 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_037842357   ⟸   XM_037986429
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842349   ⟸   XM_037986421
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842348   ⟸   XM_037986420
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842347   ⟸   XM_037986419
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842343   ⟸   XM_037986415
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842345   ⟸   XM_037986417
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842359   ⟸   XM_037986431
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842360   ⟸   XM_037986432
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842352   ⟸   XM_037986424
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842354   ⟸   XM_037986426
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842355   ⟸   XM_037986427
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842346   ⟸   XM_037986418
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842344   ⟸   XM_037986416
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842353   ⟸   XM_037986425
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842350   ⟸   XM_037986422
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842358   ⟸   XM_037986430
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842356   ⟸   XM_037986428
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0E4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000014333   ⟸   ENSCSAT00000016420


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018321 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016420.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Transcrp_activ_Zfx/Zfy-dom UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report csab:103246969 UniProtKB/TrEMBL
NCBI Gene LOC103247451 ENTREZGENE
PANTHER FEZ FAMILY ZINC FINGER PROTEIN ERM UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
  zf-H2C2_5 UniProtKB/TrEMBL
  Zfx_Zfy_act UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP beta-beta-alpha zinc fingers UniProtKB/TrEMBL
UniProt A0A0D9S0E4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 ZFX  zinc finger protein X-linked  LOC103247451  zinc finger X-chromosomal protein-like  Symbol and/or name change 5135510 APPROVED
2020-12-03 LOC103247451  zinc finger X-chromosomal protein-like  ZFX  zinc finger protein X-linked  Data merged from RGD:18419205 737654 PROVISIONAL
2020-12-03 LOC103247451  zinc finger X-chromosomal protein-like  LOC103232895  uncharacterized LOC103232895  Data merged from RGD:18464193 737654 PROVISIONAL