FBXO10 (F-box protein 10) - Rat Genome Database

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Gene: FBXO10 (F-box protein 10) Chlorocebus sabaeus
Analyze
Symbol: FBXO10
Name: F-box protein 10
RGD ID: 18478087
Description: INVOLVED IN regulation of apoptotic process (inferred); ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); distal arthrogryposis type 1A (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11243,010,040 - 43,075,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1242,992,013 - 43,074,290 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603840,063,942 - 40,143,983 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FBXO10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11243,010,040 - 43,075,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1242,992,013 - 43,074,290 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603840,063,942 - 40,143,983 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FBXO10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38937,510,892 - 37,576,380 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl937,510,892 - 37,576,380 (-)EnsemblGRCh38hg38GRCh38
GRCh37937,510,889 - 37,576,377 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36937,500,889 - 37,566,250 (-)NCBINCBI36Build 36hg18NCBI36
Build 34937,531,279 - 37,566,249NCBI
Celera937,444,118 - 37,509,479 (-)NCBICelera
Cytogenetic Map9p13.2NCBI
HuRef937,462,933 - 37,528,298 (-)NCBIHuRef
CHM1_1937,512,589 - 37,577,946 (-)NCBICHM1_1
T2T-CHM13v2.0937,534,560 - 37,600,086 (-)NCBIT2T-CHM13v2.0
Fbxo10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39445,034,248 - 45,084,555 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl445,034,247 - 45,084,604 (-)EnsemblGRCm39 Ensembl
GRCm38445,034,248 - 45,084,604 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl445,034,247 - 45,084,604 (-)EnsemblGRCm38mm10GRCm38
MGSCv37445,047,120 - 45,097,476 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36445,055,352 - 45,107,518 (-)NCBIMGSCv36mm8
Celera445,054,546 - 45,104,948 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map423.68NCBI
Fbxo10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8564,092,709 - 64,139,054 (-)NCBIGRCr8
mRatBN7.2559,297,016 - 59,343,429 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl559,297,045 - 59,343,348 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0560,589,881 - 60,636,551 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl560,591,023 - 60,658,564 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0565,098,937 - 65,145,415 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4561,601,192 - 61,626,997 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1561,600,257 - 61,668,355 (-)NCBI
Celera557,865,548 - 57,911,937 (-)NCBICelera
Cytogenetic Map5q22NCBI
Fbxo10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541928,897,288 - 28,969,374 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541928,915,083 - 28,969,374 (+)NCBIChiLan1.0ChiLan1.0
FBXO10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21187,015,023 - 87,081,740 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1987,022,136 - 87,087,686 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0937,355,861 - 37,421,321 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1938,279,653 - 38,345,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl938,279,653 - 38,345,040 (-)Ensemblpanpan1.1panPan2
FBXO10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11153,833,335 - 53,885,416 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1153,835,003 - 53,896,930 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01154,943,033 - 55,006,116 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1154,943,057 - 55,010,840 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11153,441,237 - 53,504,304 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01153,470,465 - 53,533,935 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01154,166,914 - 54,229,985 (-)NCBIUU_Cfam_GSD_1.0
Fbxo10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947168,738,262 - 168,807,656 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365245,283,828 - 5,355,392 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365245,285,844 - 5,355,212 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1238,232,867 - 238,308,625 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11238,232,855 - 238,308,661 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21266,180,500 - 266,241,944 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Fbxo10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249301,120,573 - 1,170,788 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249301,120,571 - 1,170,856 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 47
Low 20 13
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000008880   ⟹   ENSCSAP00000007014
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1242,992,013 - 43,074,290 (+)Ensembl
RefSeq Acc Id: XM_007968697   ⟹   XP_007966888
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11243,010,042 - 43,075,920 (+)NCBI
Vero_WHO_p1.0NW_02366603840,077,644 - 40,143,983 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007968701   ⟹   XP_007966892
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11243,014,654 - 43,075,920 (+)NCBI
Vero_WHO_p1.0NW_02366603840,082,772 - 40,143,983 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007968703   ⟹   XP_007966894
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11243,010,362 - 43,075,920 (+)NCBI
Vero_WHO_p1.0NW_02366603840,078,513 - 40,143,983 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037998240   ⟹   XP_037854168
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603840,063,942 - 40,143,983 (+)NCBI
RefSeq Acc Id: XM_037998241   ⟹   XP_037854169
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603840,078,344 - 40,143,983 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007966888   ⟸   XM_007968697
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007966894   ⟸   XM_007968703
- Peptide Label: isoform X2
- UniProtKB: A0A0D9REH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966892   ⟸   XM_007968701
- Peptide Label: isoform X2
- UniProtKB: A0A0D9REH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007014   ⟸   ENSCSAT00000008880
RefSeq Acc Id: XP_037854168   ⟸   XM_037998240
- Peptide Label: isoform X2
- UniProtKB: A0A0D9REH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037854169   ⟸   XM_037998241
- Peptide Label: isoform X2
- UniProtKB: A0A0D9REH5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010791 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008880.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.160.20.10 UniProtKB/TrEMBL
InterPro Beta_helix UniProtKB/TrEMBL
  Carb-bd_sugar_hydrolysis-dom UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  NosD_dom UniProtKB/TrEMBL
  Para_beta_helix_rpt-2 UniProtKB/TrEMBL
  PbH1 UniProtKB/TrEMBL
  Pectin_lyas_fold UniProtKB/TrEMBL
  Pectin_lyase_fold/virulence UniProtKB/TrEMBL
NCBI Gene FBXO10 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 10 UniProtKB/TrEMBL
Pfam Beta_helix UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
  NosD UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
SMART CASH UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
  PbH1 UniProtKB/TrEMBL
Superfamily-SCOP SSF51126 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A0D9REH5 ENTREZGENE, UniProtKB/TrEMBL