L3HYPDH (trans-L-3-hydroxyproline dehydratase) - Rat Genome Database

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Gene: L3HYPDH (trans-L-3-hydroxyproline dehydratase) Chlorocebus sabaeus
Analyze
Symbol: L3HYPDH
Name: trans-L-3-hydroxyproline dehydratase
RGD ID: 18471969
Description: ENCODES a protein that exhibits proline racemase activity (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103229097; trans-3-hydroxy-L-proline dehydratase; uncharacterized LOC103229097
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12436,701,869 - 36,714,740 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605324,940,006 - 24,969,395 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
L3HYPDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12436,701,869 - 36,714,740 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605324,940,006 - 24,969,395 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
L3HYPDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381459,465,478 - 59,505,273 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1459,460,363 - 59,484,408 (-)EnsemblGRCh38hg38GRCh38
GRCh371459,939,324 - 59,951,126 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361459,009,159 - 59,020,826 (-)NCBINCBI36Build 36hg18NCBI36
Build 341459,009,158 - 59,020,826NCBI
Celera1439,988,476 - 40,000,143 (-)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1440,103,267 - 40,114,934 (-)NCBIHuRef
CHM1_11459,877,573 - 59,889,244 (-)NCBICHM1_1
T2T-CHM13v2.01453,672,545 - 53,712,222 (-)NCBIT2T-CHM13v2.0
L3hypdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391272,114,745 - 72,132,206 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1272,120,202 - 72,132,213 (-)EnsemblGRCm39 Ensembl
GRCm381272,069,518 - 72,085,433 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1272,073,428 - 72,085,439 (-)EnsemblGRCm38mm10GRCm38
MGSCv371273,174,415 - 73,186,300 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361272,992,012 - 73,003,897 (-)NCBIMGSCv36mm8
Celera1273,184,443 - 73,196,327 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1230.2NCBI
L3hypdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8696,372,243 - 96,383,039 (-)NCBIGRCr8
mRatBN7.2690,636,310 - 90,647,106 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl690,636,310 - 90,647,106 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx691,007,072 - 91,017,975 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0691,306,536 - 91,317,439 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0690,746,092 - 90,756,995 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0694,824,112 - 94,834,908 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl694,824,112 - 94,834,908 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06104,268,771 - 104,279,567 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4694,270,120 - 94,280,916 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1694,274,037 - 94,284,075 (-)NCBI
Celera689,101,186 - 89,111,982 (-)NCBICelera
Cytogenetic Map6q24NCBI
L3hypdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546613,196,223 - 13,205,158 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546613,196,223 - 13,205,339 (-)NCBIChiLan1.0ChiLan1.0
L3HYPDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21560,605,102 - 60,617,058 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11459,821,616 - 59,833,438 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01440,075,082 - 40,107,853 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11458,339,889 - 58,372,550 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1458,339,950 - 58,351,852 (-)Ensemblpanpan1.1panPan2
L3HYPDH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1834,691,896 - 34,700,271 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl834,686,319 - 34,700,277 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha834,452,323 - 34,460,698 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0834,927,485 - 34,935,854 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl834,927,490 - 34,935,850 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1834,544,718 - 34,553,093 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0834,613,775 - 34,622,146 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0834,981,013 - 34,989,370 (-)NCBIUU_Cfam_GSD_1.0
L3hypdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864070,366,195 - 70,373,511 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364953,818,194 - 3,825,500 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
L3HYPDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1188,584,377 - 188,610,002 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11188,584,363 - 188,616,688 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
L3hypdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473441,625,812 - 41,634,884 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473441,625,899 - 41,636,907 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_007986823   ⟹   XP_007985014
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12436,701,869 - 36,714,740 (-)NCBI
Vero_WHO_p1.0NW_02366605324,957,545 - 24,969,395 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037984066   ⟹   XP_037839994
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605324,940,006 - 24,969,395 (-)NCBI
RefSeq Acc Id: XM_037984067   ⟹   XP_037839995
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605324,950,510 - 24,969,395 (-)NCBI
RefSeq Acc Id: XM_037984068   ⟹   XP_037839996
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605324,943,934 - 24,969,395 (-)NCBI
RefSeq Acc Id: XR_005235388
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605324,943,763 - 24,969,395 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007985014 (Get FASTA)   NCBI Sequence Viewer  
  XP_037839994 (Get FASTA)   NCBI Sequence Viewer  
  XP_037839995 (Get FASTA)   NCBI Sequence Viewer  
  XP_037839996 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010453.1
Reference Protein Sequences
RefSeq Acc Id: XP_007985014   ⟸   XM_007986823
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037839994   ⟸   XM_037984066
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037839996   ⟸   XM_037984068
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RPB4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037839995   ⟸   XM_037984067
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014314 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012414.1 UniProtKB/TrEMBL
InterPro Pro_racemase_fam UniProtKB/TrEMBL
NCBI Gene L3HYPDH ENTREZGENE
PANTHER TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE UniProtKB/TrEMBL
  TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE UniProtKB/TrEMBL
Pfam Pro_racemase UniProtKB/TrEMBL
PIRSF Pro_racemase UniProtKB/TrEMBL
Superfamily-SCOP Diaminopimelate epimerase-like UniProtKB/TrEMBL
UniProt A0A0D9RPB4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 L3HYPDH  trans-L-3-hydroxyproline dehydratase  LOC103229097  uncharacterized LOC103229097  Data merged from RGD:18609405 737654 PROVISIONAL