LOC103215661 (disintegrin and metalloproteinase domain-containing protein 32) - Rat Genome Database

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Gene: LOC103215661 (disintegrin and metalloproteinase domain-containing protein 32) Chlorocebus sabaeus
Analyze
Symbol: LOC103215661 (Ensembl: ADAM32)
Name: disintegrin and metalloproteinase domain-containing protein 32 (Ensembl:ADAM metallopeptidase domain 32)
RGD ID: 18467075
Description: ENCODES a protein that exhibits metalloendopeptidase activity (inferred); INVOLVED IN binding of sperm to zona pellucida (inferred); cell adhesion (inferred); male gonad development (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADAM metallopeptidase domain 32; ADAM32
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1837,132,409 - 37,284,974 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl837,133,791 - 37,283,751 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660524,689,417 - 4,847,205 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103215661
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1837,132,409 - 37,284,974 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl837,133,791 - 37,283,751 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660524,689,417 - 4,847,205 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ADAM32
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38839,107,529 - 39,284,917 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl839,106,990 - 39,284,917 (+)EnsemblGRCh38hg38GRCh38
GRCh37838,965,048 - 39,142,436 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36839,084,207 - 39,261,593 (+)NCBINCBI36Build 36hg18NCBI36
Build 34839,084,324 - 39,261,592NCBI
Celera837,916,690 - 38,094,247 (+)NCBICelera
Cytogenetic Map8p11.22NCBI
HuRef837,498,153 - 37,675,475 (+)NCBIHuRef
CHM1_1839,167,105 - 39,344,434 (+)NCBICHM1_1
T2T-CHM13v2.0839,384,664 - 39,562,013 (+)NCBIT2T-CHM13v2.0
Adam32
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39825,326,159 - 25,438,933 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl825,326,156 - 25,438,820 (-)EnsemblGRCm39 Ensembl
GRCm38824,836,143 - 24,948,918 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl824,836,140 - 24,948,804 (-)EnsemblGRCm38mm10GRCm38
MGSCv37825,946,615 - 26,059,276 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36826,301,689 - 26,414,332 (-)NCBIMGSCv36mm8
Celera826,309,930 - 26,416,097 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map813.65NCBI
Adam32
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81673,805,023 - 73,914,787 (+)NCBIGRCr8
mRatBN7.21667,102,384 - 67,212,163 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1667,102,320 - 67,212,161 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1672,379,605 - 72,489,322 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01675,785,283 - 75,894,995 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01671,033,344 - 71,138,574 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01671,889,035 - 71,999,151 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,889,235 - 71,999,148 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01671,538,126 - 71,647,772 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41671,527,593 - 71,620,315 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11671,550,906 - 71,641,753 (+)NCBI
Celera1665,006,303 - 65,114,461 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
Adam32
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555363,352,117 - 3,482,742 (-)NCBIChiLan1.0ChiLan1.0
ADAM32
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2757,668,071 - 57,853,420 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1833,385,615 - 33,570,711 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0838,408,648 - 38,592,282 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1835,583,724 - 35,766,318 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl835,583,724 - 35,766,318 (+)Ensemblpanpan1.1panPan2
ADAM32
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11626,228,380 - 26,410,634 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1626,228,415 - 26,410,583 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1626,750,011 - 26,932,252 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01628,058,373 - 28,241,585 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1628,058,376 - 28,382,944 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11626,353,463 - 26,535,878 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01626,930,158 - 27,112,653 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01626,968,171 - 27,150,845 (-)NCBIUU_Cfam_GSD_1.0
Adam32
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494348,946,408 - 49,069,462 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367102,403,994 - 2,511,771 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100525542
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1547,388,412 - 47,520,413 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11547,388,085 - 47,521,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21554,464,572 - 54,592,633 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Adam32
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247803,895,153 - 4,041,791 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 22 11 60
Below cutoff 14 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000013409   ⟹   ENSCSAP00000011410
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl837,133,791 - 37,283,751 (+)Ensembl
RefSeq Acc Id: XM_037983847   ⟹   XP_037839775
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660524,689,417 - 4,847,205 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037839775 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011410.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000011410   ⟸   ENSCSAT00000013409
RefSeq Acc Id: XP_037839775   ⟸   XM_037983847


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015351 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013409.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.390.10 UniProtKB/TrEMBL
  4.10.70.10 UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/TrEMBL
  Disintegrin_CS UniProtKB/TrEMBL
  Disintegrin_dom UniProtKB/TrEMBL
  Disintegrin_dom_sf UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  Reprolysin_adamalysin UniProtKB/TrEMBL
NCBI Gene ADAM32 ENTREZGENE
PANTHER ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN UniProtKB/TrEMBL
  DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 32 UniProtKB/TrEMBL
Pfam ADAM_CR UniProtKB/TrEMBL
  Disintegrin UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  DISINTEGRIN_1 UniProtKB/TrEMBL
  DISINTEGRIN_2 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  DISIN UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF57552 UniProtKB/TrEMBL
UniProt A0A0D9RS21_CHLSB UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103215661  disintegrin and metalloproteinase domain-containing protein 32  ADAM32  ADAM metallopeptidase domain 32  Symbol and/or name change 5135510 APPROVED