STARD8 (StAR related lipid transfer domain containing 8) - Rat Genome Database

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Gene: STARD8 (StAR related lipid transfer domain containing 8) Chlorocebus sabaeus
Analyze
Symbol: STARD8
Name: StAR related lipid transfer domain containing 8
RGD ID: 18464432
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN actin cytoskeleton organization (inferred); regulation of Rho protein signal transduction (inferred); signal transduction (inferred); ASSOCIATED WITH autistic disorder (ortholog); Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: stAR-related lipid transfer protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X58,487,688 - 58,569,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX58,556,806 - 58,566,551 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666065342,579 - 420,535 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STARD8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X58,487,688 - 58,569,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX58,556,806 - 58,566,551 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666065342,579 - 420,535 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STARD8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X68,647,666 - 68,725,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX68,647,666 - 68,725,842 (+)EnsemblGRCh38hg38GRCh38
GRCh37X67,867,508 - 67,945,678 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X67,784,236 - 67,862,403 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X67,650,531 - 67,728,698NCBI
CeleraX68,220,334 - 68,298,611 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX61,695,452 - 61,772,608 (+)NCBIHuRef
CHM1_1X67,760,683 - 67,838,871 (+)NCBICHM1_1
T2T-CHM13v2.0X67,081,162 - 67,159,288 (+)NCBIT2T-CHM13v2.0
Stard8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X98,046,539 - 98,118,334 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX98,046,854 - 98,118,334 (+)EnsemblGRCm39 Ensembl
GRCm38X99,002,933 - 99,074,728 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX99,003,248 - 99,074,728 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X96,237,920 - 96,270,067 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X95,245,384 - 95,277,447 (+)NCBIMGSCv36mm8
CeleraX85,983,748 - 86,015,610 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.19NCBI
Stard8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X68,119,276 - 68,236,247 (+)NCBIGRCr8
mRatBN7.2X64,079,079 - 64,196,052 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX64,124,574 - 64,196,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX65,665,621 - 65,679,569 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X69,165,962 - 69,179,914 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X66,726,912 - 66,740,854 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X68,713,157 - 68,785,046 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX68,713,123 - 68,785,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X69,587,772 - 69,659,522 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X87,088,565 - 87,102,511 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX64,551,816 - 64,565,762 (+)NCBICelera
Cytogenetic MapXq22NCBI
Stard8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554758,245,754 - 8,278,319 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554758,203,624 - 8,278,319 (+)NCBIChiLan1.0ChiLan1.0
STARD8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X68,299,028 - 68,377,083 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X68,302,603 - 68,380,880 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X57,890,362 - 57,968,391 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X67,955,393 - 68,031,958 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX67,954,883 - 68,031,958 (+)Ensemblpanpan1.1panPan2
STARD8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X53,128,122 - 53,211,115 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX53,128,095 - 53,210,852 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX43,953,760 - 44,036,713 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X54,087,072 - 54,170,149 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX54,086,983 - 54,169,887 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X52,061,722 - 52,144,669 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X53,390,428 - 53,473,431 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X53,314,126 - 53,397,128 (+)NCBIUU_Cfam_GSD_1.0
Stard8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X48,876,064 - 48,953,571 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936777323,367 - 358,243 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936777316,332 - 358,241 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STARD8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX54,773,171 - 54,856,711 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X54,773,189 - 54,856,716 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X61,989,481 - 62,001,599 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Stard8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248911,508,980 - 1,547,811 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248911,509,113 - 1,540,416 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 17 17
Low 19 20 43
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007991944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037988889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037988890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037988891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037988892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_497067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000009889   ⟹   ENSCSAP00000007995
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblX58,556,806 - 58,566,551 (+)Ensembl
RefSeq Acc Id: XM_007991947   ⟹   XP_007990138
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X58,529,709 - 58,569,704 (+)NCBI
Vero_WHO_p1.0NW_023666065381,196 - 420,535 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007991948   ⟹   XP_007990139
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X58,487,712 - 58,569,704 (+)NCBI
Vero_WHO_p1.0NW_023666065342,590 - 420,535 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007991949   ⟹   XP_007990140
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X58,487,713 - 58,569,710 (+)NCBI
Vero_WHO_p1.0NW_023666065342,579 - 420,529 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007991953   ⟹   XP_007990144
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X58,537,422 - 58,569,704 (+)NCBI
Vero_WHO_p1.0NW_023666065388,314 - 420,535 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007991954   ⟹   XP_007990145
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X58,537,423 - 58,569,704 (+)NCBI
Vero_WHO_p1.0NW_023666065388,328 - 420,228 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037988889   ⟹   XP_037844817
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666065393,701 - 420,535 (+)NCBI
RefSeq Acc Id: XM_037988890   ⟹   XP_037844818
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666065393,708 - 420,535 (+)NCBI
RefSeq Acc Id: XM_037988891   ⟹   XP_037844819
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666065388,563 - 420,535 (+)NCBI
RefSeq Acc Id: XM_037988892   ⟹   XP_037844820
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666065393,682 - 417,805 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007990139   ⟸   XM_007991948
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007990140   ⟸   XM_007991949
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007990138   ⟸   XM_007991947
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007990144   ⟸   XM_007991953
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007990145   ⟸   XM_007991954
- Peptide Label: isoform X6
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007995   ⟸   ENSCSAT00000009889
RefSeq Acc Id: XP_037844819   ⟸   XM_037988891
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037844820   ⟸   XM_037988892
- Peptide Label: isoform X7
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037844817   ⟸   XM_037988889
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037844818   ⟸   XM_037988890
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RHA6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011822 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009889.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2070 UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/TrEMBL
InterPro Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
NCBI Gene STARD8 ENTREZGENE
PANTHER RHO-TYPE GTPASE ACTIVATING PROTEIN UniProtKB/TrEMBL
  STAR-RELATED LIPID TRANSFER PROTEIN 8 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
UniProt A0A0D9RHA6 ENTREZGENE, UniProtKB/TrEMBL