HMOX2 (heme oxygenase 2) - Rat Genome Database

Name: HMOX2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: HMOX2 (heme oxygenase 2) Chlorocebus sabaeus

Analyze

Symbol:

HMOX2

Name:

heme oxygenase 2

RGD ID:

18460415

Description:

ENCODES a protein that exhibits heme oxygenase (decyclizing) activity (ortholog); INVOLVED IN response to hypoxia (ortholog); response to oxidative stress (ortholog); ASSOCIATED WITH Cerebral Hemorrhage (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HMOX2 (heme oxygenase 2)	NCBI	Ortholog
Mus musculus (house mouse):	Hmox2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Hmox2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hmox2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HMOX2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HMOX2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hmox2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HMOX2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hmox2 (heme oxygenase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	4,157,402 - 4,201,223 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666068	26,486,456 - 26,522,635 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cerebral Hemorrhage (ISO)

epilepsy (ISO)

genetic disease (ISO)

idiopathic generalized epilepsy (ISO)

Kohlschutter-Tonz syndrome (ISO)

migraine with aura (ISO)

Rubinstein-Taybi syndrome (ISO)

short-rib thoracic dysplasia 9 with or without polydactyly (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

response to hypoxia (ISO)

response to oxidative stress (ISO)

Cellular Component

plasma membrane (ISO)

Molecular Function

heme oxygenase (decyclizing) activity (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

HMOX2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	4,157,402 - 4,201,223 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666068	26,486,456 - 26,522,635 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

HMOX2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	4,474,736 - 4,510,347 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	4,474,690 - 4,510,347 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	4,524,737 - 4,560,348 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	4,466,447 - 4,500,349 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	4,466,446 - 4,500,348	NCBI
Celera	16	4,733,625 - 4,769,241 (+)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	4,492,031 - 4,527,516 (+)	NCBI		HuRef
CHM1_1	16	4,524,657 - 4,560,277 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	4,504,257 - 4,539,822 (+)	NCBI		T2T-CHM13v2.0

Hmox2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	4,544,225 - 4,584,606 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	4,544,225 - 4,584,606 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	4,726,361 - 4,766,742 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	4,726,361 - 4,766,742 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	4,726,361 - 4,766,249 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	4,656,841 - 4,681,476 (+)	NCBI		MGSCv36	mm8
Celera	16	5,357,042 - 5,398,127 (+)	NCBI		Celera
Cytogenetic Map	16	A1	NCBI
cM Map	16	2.46	NCBI

Hmox2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	11,303,512 - 11,337,640 (-)	NCBI		GRCr8
mRatBN7.2	10	10,797,076 - 10,831,178 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	10,797,055 - 10,831,148 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	15,505,604 - 15,539,849 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	14,994,426 - 15,028,671 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	10,663,877 - 10,698,152 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	10,990,034 - 11,035,493 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	10,990,034 - 11,035,484 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	9,756,647 - 9,800,842 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	10,914,157 - 10,929,448 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	10,914,156 - 10,929,448 (-)	NCBI
Celera	10	9,760,483 - 9,793,519 (-)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

Hmox2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	12,913,983 - 12,920,152 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	12,913,983 - 12,947,412 (-)	NCBI	ChiLan1.0	ChiLan1.0

HMOX2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	5,004,553 - 5,040,043 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	8,794,278 - 8,830,538 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	3,399,715 - 3,436,018 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	4,567,825 - 4,604,596 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	4,567,828 - 4,604,596 (+)	Ensembl	panpan1.1		panPan2

HMOX2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	36,881,073 - 36,898,062 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	36,881,506 - 36,898,042 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	38,209,606 - 38,240,992 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	37,085,031 - 37,117,118 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	37,085,038 - 37,117,547 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	36,879,455 - 36,911,205 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	36,772,360 - 36,804,385 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	37,174,250 - 37,205,632 (-)	NCBI		UU_Cfam_GSD_1.0

Hmox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	106,695,873 - 106,712,812 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	4,556,706 - 4,557,663 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	4,556,617 - 4,558,250 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HMOX2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	37,831,439 - 37,868,128 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	37,829,044 - 37,868,163 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	38,887,097 - 38,923,044 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Hmox2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624824	2,272,515 - 2,317,115 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007984272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037989905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_007984272 ⟹ XP_007982463

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	4,157,402 - 4,201,223 (+)	NCBI
Vero_WHO_p1.0	NW_023666068	26,486,456 - 26,522,635 (-)	NCBI

Sequence:

show sequence

TGCACCGGCCTTCGCGCCAGTCCGCTGGGCTGCCGGGACTGCGGCGCCTGAGGGAGTCGCTGAC
GGGCAAGCTGAGTGGAGGCTGGCGGACGGGCCACAGCGACCTGCCGCAGGACCAGAGTGAGAGC
AGCAAGAACCACACCCAGCAGCAATGTCAGCGGAAGTGGAAACCTCAGAAGGGGTAGATGAATC
AGAGAAAAAGAACTCTGGGGCCTTAGAAAAGGAGAACCAAATGAGAATGGCTGACCTCTCGGAG
CTCCTGAAGGAAGGGACCAAGGAAGCACACGACCGGGCAGAAAACACCCAGTTTGTCAAGGACT
TCTTGAAAGGCAACATTAAGAAGGAGCTGTTTAAGCTGGCCACCACGGCACTTTACTTTACATA
CTCAGCCCTCGAGGAGGAAATGGAGCGCAACAAGGACCATCCAGCCTTTGCCCCCTTGTACTTC
CCCATGGAGCTGCACCGGAAGGAGGCGTTGACCAAGGACATGGAATATTTCTTTGGTGAAAACT
GGGAGGAGCAGGTGCAGTGCCCCAAGGCTGCCAAAAAGTAGGTGGAGCGGATCCACTACATAGG
GCAGAATGAGCCGGAGCTACTGGTGGCCCATGCGTACACCCGCTACATGGGGGACCTCTCGGGG
GGCCAGGTGCTGAAGAAGGTGGCCCAGCGAGCACTGAAACTCCCCAGCACAGGGGAAGGGACCC
AGTTCTACCTGTTTGAGAATGTGGACAATGCCCAGCAGTTCAAGCAGCTCTACCGAGCCAGGAT
GAACGCCCTGGACCTGAACATGAAGACCAAAGAGAGGATCGTGGAGGAGGCCAACAAGGCTTTT
GAGTATAACATGCAGATATTCAATGAACTGGACCAGGCTGGCTCCACGCTGGCCAGAGAGACCT
TGGAGGATGGGTTCCCTGTACACGATGGGAAAGGAGACAGGCGTAAATGCCCTTTCTACGCTGG
TGAGCAAGACAAAGGTGCCCTGGAGGGCAGCAGCTGTCCCTTCCGAACAGCCATGGCTGTGCTG
AGGAAGCCCAGCCTCCAGTTCATCCTGGCCGCTGGCATGGCCCTAGCTGCTGGACTCTTGGCCT
GGTACTACATGTGAAGGACCCATCATGCCATGCCGGTACCCTCCTCCCGACTGACCACTGGCCT
ACCCCTTTCTCCAGCCCTGACTAAACTACCACCTCAGGTGACTTTTTAAAAAATGCTGGGTTTA
AGAAAGGCAACCAATAAAAGCCAGATGCTAGAGCCTCTGCCTGACAGCATCCTCTCCATGGGCC
AGATTCTGCCCTGGGCACAGGGTGTCACCCTGGGAGCAGTCGGCACAGTGCAGCAGGCCTGGCC
TCCGACCCAGCTCTAGTCCAGGCTCCCACACCTCTGGGCCCTAGGCTGCTTCCAGTAAAGTAGT
TCCTGTTTTTGTAGTACATGGGTGGCTGTCTCCCCTGCTGGAGGTGAGTGGCCTGTAAGCCCAG
GCTGTGGGAGGGGCCTTGCTGGATGCTGCTGTACTACTTCTGGGCCTCTCTTGGACCCTGGGGG
TGAGGGTGGGTGTGGGTGGAAGCCTCAGAGGCCTTGGGAGCTTATCCCTCTCACCCAGAATCCC
TCTAACCCCTTGGGTGAGGTCTGCTTGGCCCCAGCTTGTCTTGTCTCCTCCTCCGCCCTGTGTA
AATGCTCCAGCACTCAATAAAGTGGGCTTTGCAAGCTG

hide sequence

RefSeq Acc Id:

XM_037989905 ⟹ XP_037845833

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666068	26,486,456 - 26,502,010 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007982463	(Get FASTA)	NCBI Sequence Viewer
	XP_037845833	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_007982463 ⟸ XM_007984272

RefSeq Acc Id:

XP_037845833 ⟸ XM_037989905

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	HMOX2	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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