STK36 (serine/threonine kinase 36) - Rat Genome Database

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Gene: STK36 (serine/threonine kinase 36) Chlorocebus sabaeus
Analyze
Symbol: STK36
Name: serine/threonine kinase 36
RGD ID: 18459173
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH alacrima, achalasia, and impaired intellectual development syndrome (ortholog); cerebrotendinous xanthomatosis (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase 36
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,575,944 - 104,606,923 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,576,666 - 104,607,946 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604094,796,639 - 94,827,896 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STK36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,575,944 - 104,606,923 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,576,666 - 104,607,946 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604094,796,639 - 94,827,896 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STK36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,672,086 - 218,702,717 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,672,069 - 218,702,716 (+)EnsemblGRCh38hg38GRCh38
GRCh372219,536,809 - 219,567,440 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,245,053 - 219,275,682 (+)NCBINCBI36Build 36hg18NCBI36
Build 342219,362,313 - 219,392,941NCBI
Celera2213,304,520 - 213,335,199 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,390,237 - 211,420,674 (+)NCBIHuRef
CHM1_12219,543,724 - 219,574,415 (+)NCBICHM1_1
T2T-CHM13v2.02219,158,642 - 219,189,274 (+)NCBIT2T-CHM13v2.0
Stk36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,640,583 - 74,676,053 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,640,604 - 74,676,053 (+)EnsemblGRCm39 Ensembl
GRCm38174,601,391 - 74,636,894 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,601,445 - 74,636,894 (+)EnsemblGRCm38mm10GRCm38
MGSCv37174,648,029 - 74,683,468 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,534,662 - 74,570,101 (+)NCBIMGSCv36mm8
Celera175,159,205 - 75,191,773 (+)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.54NCBI
Stk36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,625,905 - 83,652,785 (+)NCBIGRCr8
mRatBN7.2976,176,922 - 76,204,423 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,176,920 - 76,204,422 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,622,018 - 84,648,782 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,750,967 - 89,777,733 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,137,150 - 88,163,909 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0981,880,175 - 81,908,014 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,880,177 - 81,907,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,642,521 - 81,670,396 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,951,045 - 73,977,783 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1974,098,074 - 74,172,103 (+)NCBI
Celera973,749,615 - 73,776,292 (+)NCBICelera
Cytogenetic Map9q33NCBI
Stk36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545314,728,583 - 14,753,534 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545314,727,779 - 14,753,534 (-)NCBIChiLan1.0ChiLan1.0
STK36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213121,302,824 - 121,333,564 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B121,317,790 - 121,350,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B105,930,030 - 105,960,718 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B224,525,226 - 224,555,583 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B224,525,226 - 224,555,583 (+)Ensemblpanpan1.1panPan2
STK36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,273,237 - 25,297,794 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3725,273,110 - 25,340,512 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,092,722 - 26,117,828 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03725,288,815 - 25,313,775 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3725,289,474 - 25,313,763 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,194,021 - 25,218,588 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,127,869 - 25,152,844 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,148,483 - 25,173,652 (+)NCBIUU_Cfam_GSD_1.0
Stk36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,772,981 - 174,800,458 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,115,768 - 1,143,370 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,115,790 - 1,143,450 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15120,719,646 - 120,754,065 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115120,719,635 - 120,747,832 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Stk36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248236,360,242 - 6,383,035 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248236,359,868 - 6,383,777 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 26 34
Low 10 18 26
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000006726   ⟹   ENSCSAP00000004923
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl10104,576,666 - 104,607,946 (+)Ensembl
RefSeq Acc Id: XM_007966303   ⟹   XP_007964494
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.110104,576,141 - 104,606,923 (+)NCBI
Vero_WHO_p1.0NW_02366604094,796,639 - 94,827,735 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007966304   ⟹   XP_007964495
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.110104,575,944 - 104,606,919 (+)NCBI
Vero_WHO_p1.0NW_02366604094,796,639 - 94,827,896 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007966305   ⟹   XP_007964496
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.110104,576,140 - 104,606,923 (+)NCBI
Vero_WHO_p1.0NW_02366604094,796,639 - 94,827,735 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038001519   ⟹   XP_037857447
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604094,796,639 - 94,827,735 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007964494 (Get FASTA)   NCBI Sequence Viewer  
  XP_007964495 (Get FASTA)   NCBI Sequence Viewer  
  XP_007964496 (Get FASTA)   NCBI Sequence Viewer  
  XP_037857447 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004923.1
Reference Protein Sequences
RefSeq Acc Id: XP_007964495   ⟸   XM_007966304
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007964496   ⟸   XM_007966305
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007964494   ⟸   XM_007966303
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000004923   ⟸   ENSCSAT00000006726
RefSeq Acc Id: XP_037857447   ⟸   XM_038001519
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R8I4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008730 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006726.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  HEAT_type_2 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene STK36 ENTREZGENE
PANTHER PTHR22983 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE 36 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE HEAT_REPEAT UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9R8I4 ENTREZGENE, UniProtKB/TrEMBL