CNST (consortin, connexin sorting protein) - Rat Genome Database

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Gene: CNST (consortin, connexin sorting protein) Chlorocebus sabaeus
Analyze
Symbol: CNST
Name: consortin, connexin sorting protein
RGD ID: 18454950
Description: ENCODES a protein that exhibits connexin binding (inferred); phosphatase binding (inferred); INVOLVED IN positive regulation of Golgi to plasma membrane protein transport (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 54 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: consortin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12583,592,133 - 83,706,703 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2583,595,348 - 83,706,697 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605585,869,816 - 85,986,093 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CNST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12583,592,133 - 83,706,703 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2583,595,348 - 83,706,697 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605585,869,816 - 85,986,093 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CNST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381246,566,456 - 246,668,595 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1246,566,444 - 246,668,595 (+)EnsemblGRCh38hg38GRCh38
GRCh371246,729,758 - 246,831,897 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361244,796,429 - 244,897,049 (+)NCBINCBI36Build 36hg18NCBI36
Celera1220,016,987 - 220,121,650 (+)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1217,115,430 - 217,192,622 (+)NCBIHuRef
HuRef1217,197,253 - 217,218,839 (+)NCBIHuRef
CHM1_11248,001,936 - 248,104,308 (+)NCBICHM1_1
T2T-CHM13v2.01245,987,346 - 246,091,605 (+)NCBIT2T-CHM13v2.0
Cnst
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391179,374,009 - 179,455,043 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1179,373,935 - 179,455,043 (+)EnsemblGRCm39 Ensembl
GRCm381179,546,444 - 179,627,478 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1179,546,370 - 179,627,478 (+)EnsemblGRCm38mm10GRCm38
MGSCv371181,476,660 - 181,557,604 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361181,383,204 - 181,464,148 (+)NCBIMGSCv36mm8
Celera1186,617,507 - 186,698,192 (+)NCBICelera
Cytogenetic Map1H4NCBI
cM Map183.57NCBI
Cnst
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81393,828,694 - 93,905,497 (+)NCBIGRCr8
mRatBN7.21391,296,740 - 91,373,531 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1391,296,142 - 91,373,531 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01397,838,325 - 97,915,131 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1397,838,361 - 97,913,082 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013102,848,124 - 102,925,145 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41395,246,290 - 95,323,173 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1390,847,901 - 90,924,738 (+)NCBICelera
Cytogenetic Map13q26NCBI
Cnst
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554069,473,398 - 9,529,996 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554069,441,441 - 9,531,792 (+)NCBIChiLan1.0ChiLan1.0
CNST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212,457,842 - 2,565,803 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112,675,362 - 2,782,529 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01222,184,419 - 222,291,611 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11227,538,079 - 227,761,748 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1227,563,246 - 227,759,310 (+)Ensemblpanpan1.1panPan2
CNST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1737,278,479 - 37,400,847 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl737,328,609 - 37,399,390 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha736,760,942 - 36,883,324 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0737,110,754 - 37,233,436 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl737,110,562 - 37,233,434 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1736,950,992 - 37,073,299 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0736,958,988 - 37,081,302 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0737,227,926 - 37,350,341 (+)NCBIUU_Cfam_GSD_1.0
Cnst
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934450,250,159 - 50,347,933 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365264,397,357 - 4,497,850 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365264,399,886 - 4,497,185 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1019,046,429 - 19,139,655 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11019,046,384 - 19,139,662 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21021,753,164 - 21,762,574 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cnst
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477113,021,322 - 13,082,776 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477113,012,415 - 13,115,092 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 17 47
Low 3 13
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000007195   ⟹   ENSCSAP00000005380
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2583,595,348 - 83,706,697 (+)Ensembl
RefSeq Acc Id: XM_007990031   ⟹   XP_007988222
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12583,592,133 - 83,706,703 (+)NCBI
Vero_WHO_p1.0NW_02366605585,869,816 - 85,986,093 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007990032   ⟹   XP_007988223
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12583,592,300 - 83,706,703 (+)NCBI
Vero_WHO_p1.0NW_02366605585,869,830 - 85,986,093 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037986098   ⟹   XP_037842026
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,870,039 - 85,986,093 (+)NCBI
RefSeq Acc Id: XM_037986099   ⟹   XP_037842027
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,870,011 - 85,985,882 (+)NCBI
RefSeq Acc Id: XM_037986100   ⟹   XP_037842028
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,870,039 - 85,986,093 (+)NCBI
RefSeq Acc Id: XM_037986101   ⟹   XP_037842029
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,869,816 - 85,975,267 (+)NCBI
RefSeq Acc Id: XM_037986102   ⟹   XP_037842030
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,869,928 - 85,985,882 (+)NCBI
RefSeq Acc Id: XM_037986103   ⟹   XP_037842031
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,870,017 - 85,985,882 (+)NCBI
RefSeq Acc Id: XM_037986104   ⟹   XP_037842032
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,869,924 - 85,985,882 (+)NCBI
RefSeq Acc Id: XM_037986105   ⟹   XP_037842033
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605585,948,265 - 85,986,093 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007988222   ⟸   XM_007990031
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R9U1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007988223   ⟸   XM_007990032
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000005380   ⟸   ENSCSAT00000007195
RefSeq Acc Id: XP_037842029   ⟸   XM_037986101
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037842032   ⟸   XM_037986104
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037842030   ⟸   XM_037986102
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037842027   ⟸   XM_037986099
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R9U1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842031   ⟸   XM_037986103
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037842026   ⟸   XM_037986098
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R9U1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842028   ⟸   XM_037986100
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R9U1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842033   ⟸   XM_037986105
- Peptide Label: isoform X6


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009127 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007195.1 UniProtKB/TrEMBL
InterPro Consortin UniProtKB/TrEMBL
  Consortin_C UniProtKB/TrEMBL
NCBI Gene CNST ENTREZGENE
PANTHER CONSORTIN UniProtKB/TrEMBL
  PTHR28581 UniProtKB/TrEMBL
Pfam Consortin_C UniProtKB/TrEMBL
UniProt A0A0D9R9U1 ENTREZGENE, UniProtKB/TrEMBL