GJC1 (gap junction protein gamma 1) - Rat Genome Database

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Gene: GJC1 (gap junction protein gamma 1) Chlorocebus sabaeus
Analyze
Symbol: GJC1
Name: gap junction protein gamma 1
RGD ID: 18453935
Description: ENCODES a protein that exhibits gap junction channel activity (ortholog); INVOLVED IN cardiac muscle tissue development (ortholog); cell development (ortholog); cell-cell signaling (ortholog); PARTICIPATES IN connexin signaling pathway; ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); hypertension (ortholog); FOUND IN gap junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gap junction gamma-1 protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11661,575,851 - 61,596,488 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1661,594,885 - 61,596,075 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607732,322,168 - 32,350,709 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GJC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11661,575,851 - 61,596,488 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1661,594,885 - 61,596,075 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607732,322,168 - 32,350,709 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GJC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381744,794,104 - 44,831,364 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1744,798,448 - 44,830,816 (-)EnsemblGRCh38hg38GRCh38
GRCh371742,875,816 - 42,908,202 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361740,231,342 - 40,263,705 (-)NCBINCBI36Build 36hg18NCBI36
Build 341740,237,520 - 40,238,711NCBI
Celera1739,586,320 - 39,618,684 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1738,640,950 - 38,673,263 (-)NCBIHuRef
CHM1_11743,111,947 - 43,144,318 (-)NCBICHM1_1
T2T-CHM13v2.01745,648,941 - 45,685,306 (-)NCBIT2T-CHM13v2.0
Gjc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911102,690,303 - 102,710,512 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11102,690,405 - 102,710,526 (-)EnsemblGRCm39 Ensembl
GRCm3811102,799,477 - 102,819,686 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11102,799,579 - 102,819,700 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711102,660,792 - 102,681,000 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,615,669 - 102,620,731 (-)NCBIMGSCv36mm8
Celera11114,511,245 - 114,530,176 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1166.48NCBI
Gjc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81088,262,840 - 88,285,646 (-)NCBIGRCr8
mRatBN7.21087,758,192 - 87,785,443 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1087,760,528 - 87,785,867 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1092,799,858 - 92,820,614 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01092,266,006 - 92,286,621 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01087,659,342 - 87,679,956 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01090,781,408 - 90,912,440 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1090,781,402 - 90,912,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01090,573,861 - 90,576,546 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01090,684,903 - 90,685,231 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1086,466,836 - 86,488,023 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Gjc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545117,626,859 - 17,630,247 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545117,626,859 - 17,639,002 (-)NCBIChiLan1.0ChiLan1.0
GJC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21920,002,494 - 20,040,325 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11721,971,082 - 22,003,446 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01712,492,285 - 12,524,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11712,663,614 - 12,696,618 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1712,689,251 - 12,690,441 (+)Ensemblpanpan1.1panPan2
GJC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1918,642,359 - 18,688,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl918,686,527 - 18,687,717 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha918,071,974 - 18,073,164 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0919,336,722 - 19,382,385 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl919,337,429 - 19,382,482 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1918,234,973 - 18,235,559 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0918,416,349 - 18,417,539 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0918,573,413 - 18,574,603 (+)NCBIUU_Cfam_GSD_1.0
Gjc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560217,990,495 - 18,016,917 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365411,178,493 - 1,182,967 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365411,177,581 - 1,182,967 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GJC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1218,526,595 - 18,560,218 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11218,526,060 - 18,560,221 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,770,695 - 18,795,440 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Gjc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624795461,691 - 464,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624795443,234 - 466,222 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 19 35 35 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000019111   ⟹   ENSCSAP00000018533
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1661,594,885 - 61,596,075 (+)Ensembl
RefSeq Acc Id: XM_008012392   ⟹   XP_008010583
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11661,576,747 - 61,596,488 (+)NCBI
Vero_WHO_p1.0NW_02366607732,322,544 - 32,350,709 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012394   ⟹   XP_008010585
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11661,575,851 - 61,596,488 (+)NCBI
Vero_WHO_p1.0NW_02366607732,322,168 - 32,350,709 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008010583 (Get FASTA)   NCBI Sequence Viewer  
  XP_008010585 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018533
  ENSCSAP00000018533.1
RefSeq Acc Id: XP_008010585   ⟸   XM_008012394
- UniProtKB: A0A0D9SCE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008010583   ⟸   XM_008012392
- UniProtKB: A0A0D9SCE4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000018533   ⟸   ENSCSAT00000019111


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019021 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019111.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1440.80 UniProtKB/TrEMBL
InterPro Connexin UniProtKB/TrEMBL
  Connexin45 UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
  Connexin_CS UniProtKB/TrEMBL
  Connexin_N UniProtKB/TrEMBL
  Connexin_N_sf UniProtKB/TrEMBL
KEGG Report csab:103243312 UniProtKB/TrEMBL
NCBI Gene GJC1 ENTREZGENE
PANTHER GAP JUNCTION GAMMA-1 PROTEIN UniProtKB/TrEMBL
  PTHR11984 UniProtKB/TrEMBL
Pfam Connexin UniProtKB/TrEMBL
PRINTS CONNEXIN UniProtKB/TrEMBL
  CONNEXINA6 UniProtKB/TrEMBL
PROSITE CONNEXINS_1 UniProtKB/TrEMBL
  CONNEXINS_2 UniProtKB/TrEMBL
SMART CNX UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
UniProt A0A0D9SCE4 ENTREZGENE, UniProtKB/TrEMBL