ENTREP3 (endosomal transmembrane epsin interactor 3) - Rat Genome Database

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Gene: ENTREP3 (endosomal transmembrane epsin interactor 3) Chlorocebus sabaeus
Analyze
Symbol: ENTREP3
Name: endosomal transmembrane epsin interactor 3
RGD ID: 18446193
Description: ENCODES a protein that exhibits WW domain binding (inferred); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAM189B; family with sequence similarity 189 member B; protein FAM189B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1208,578,983 - 8,587,181 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl208,579,435 - 8,587,399 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660387,921,846 - 7,929,977 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ENTREP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1208,578,983 - 8,587,181 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl208,579,435 - 8,587,399 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660387,921,846 - 7,929,977 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ENTREP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381155,247,205 - 155,255,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1155,247,205 - 155,255,483 (-)EnsemblGRCh38hg38GRCh38
GRCh371155,216,996 - 155,225,274 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361153,483,620 - 153,491,898 (-)NCBINCBI36Build 36hg18NCBI36
Celera1128,290,272 - 128,298,549 (-)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1126,579,293 - 126,587,583 (-)NCBIHuRef
CHM1_11156,612,488 - 156,620,740 (-)NCBICHM1_1
T2T-CHM13v2.01154,385,763 - 154,394,041 (-)NCBIT2T-CHM13v2.0
Entrep3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,089,996 - 89,096,598 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,090,450 - 89,096,602 (+)EnsemblGRCm39 Ensembl
GRCm38389,183,143 - 89,189,291 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,183,143 - 89,189,295 (+)EnsemblGRCm38mm10GRCm38
MGSCv37388,987,147 - 88,993,211 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,269,152 - 89,275,216 (+)NCBIMGSCv36mm8
Celera389,216,901 - 89,222,963 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.01NCBI
Entrep3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82176,886,903 - 176,893,047 (+)NCBIGRCr8
mRatBN7.22174,588,984 - 174,595,281 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2174,589,337 - 174,595,281 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2181,735,436 - 181,741,257 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02179,757,809 - 179,763,630 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,357,680 - 174,363,500 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02188,495,237 - 188,501,444 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2188,495,629 - 188,501,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,911,548 - 207,917,769 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,264,184 - 181,270,006 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12181,214,254 - 181,220,110 (+)NCBI
Celera2168,531,896 - 168,537,711 (+)NCBICelera
Cytogenetic Map2q34NCBI
Entrep3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,704,422 - 1,709,605 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,703,860 - 1,710,120 (-)NCBIChiLan1.0ChiLan1.0
ENTREP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2194,588,165 - 94,596,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,319,477 - 94,328,133 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01130,592,215 - 130,600,884 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11134,197,364 - 134,205,814 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,197,555 - 134,205,476 (-)Ensemblpanpan1.1panPan2
ENTREP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,299,568 - 42,305,177 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,300,009 - 42,372,615 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,790,452 - 41,796,070 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,168,765 - 42,174,383 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,168,798 - 42,174,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,948,599 - 41,954,216 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,002,514 - 42,008,132 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,286,389 - 42,292,007 (+)NCBIUU_Cfam_GSD_1.0
Entrep3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,702,708 - 25,709,770 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,731,036 - 4,740,099 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,733,083 - 4,740,136 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENTREP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,575,793 - 94,581,585 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,575,752 - 94,581,587 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,357,892 - 103,363,812 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Entrep3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,302,530 - 2,307,299 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,301,637 - 2,307,839 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 5 6
Low 31 18 54
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000016515   ⟹   ENSCSAP00000016021
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl208,579,435 - 8,587,399 (+)Ensembl
RefSeq Acc Id: XM_007976859   ⟹   XP_007975050
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1208,578,983 - 8,586,871 (+)NCBI
Vero_WHO_p1.0NW_0236660387,921,846 - 7,929,976 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007976860   ⟹   XP_007975051
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1208,578,983 - 8,587,168 (+)NCBI
Vero_WHO_p1.0NW_0236660387,921,846 - 7,929,965 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007976862   ⟹   XP_007975053
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1208,578,983 - 8,587,181 (+)NCBI
Vero_WHO_p1.0NW_0236660387,921,846 - 7,929,977 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007975050 (Get FASTA)   NCBI Sequence Viewer  
  XP_007975051 (Get FASTA)   NCBI Sequence Viewer  
  XP_007975053 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016021.1
Reference Protein Sequences
RefSeq Acc Id: XP_007975053   ⟸   XM_007976862
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S582 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007975051   ⟸   XM_007976860
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S582 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007975050   ⟸   XM_007976859
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S582 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000016021   ⟸   ENSCSAT00000016515


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002013 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016515.1 UniProtKB/TrEMBL
InterPro CD20-like UniProtKB/TrEMBL
  FAM189 UniProtKB/TrEMBL
NCBI Gene FAM189B ENTREZGENE
PANTHER PROTEIN FAM189B UniProtKB/TrEMBL
  PTHR17615 UniProtKB/TrEMBL
Pfam CD20 UniProtKB/TrEMBL
UniProt A0A0D9S582 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-07 ENTREP3  endosomal transmembrane epsin interactor 3  FAM189B  family with sequence similarity 189 member B  Symbol and/or name change 5135510 APPROVED