RAP1B (RAP1B, member of RAS oncogene family) - Rat Genome Database

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Gene: RAP1B (RAP1B, member of RAS oncogene family) Chlorocebus sabaeus
Analyze
Symbol: RAP1B
Name: RAP1B, member of RAS oncogene family
RGD ID: 18430095
Description: ENCODES a protein that exhibits G protein activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); cell population proliferation (ortholog); cellular response to gonadotropin-releasing hormone (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; platelet-derived growth factor signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); Thrombocytopenia 11 (ortholog); FOUND IN cell-cell junction (ortholog); glutamatergic synapse (ortholog); lipid droplet (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rap-1b
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11164,240,501 - 64,290,515 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1164,240,651 - 64,286,727 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037181,414,337 - 181,465,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAP1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11164,240,501 - 64,290,515 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1164,240,651 - 64,286,727 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037181,414,337 - 181,465,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAP1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381268,610,899 - 68,671,901 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1268,610,855 - 68,671,901 (+)EnsemblGRCh38hg38GRCh38
GRCh371269,004,679 - 69,065,681 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361267,290,919 - 67,340,641 (+)NCBINCBI36Build 36hg18NCBI36
Build 341267,290,918 - 67,340,644NCBI
Celera1268,668,392 - 68,717,826 (+)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1266,093,121 - 66,105,030 (+)NCBIHuRef
CHM1_11268,972,799 - 69,022,538 (+)NCBICHM1_1
T2T-CHM13v2.01268,590,436 - 68,651,443 (+)NCBIT2T-CHM13v2.0
Rap1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910117,650,502 - 117,681,879 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10117,649,776 - 117,681,940 (-)EnsemblGRCm39 Ensembl
GRCm3810117,814,597 - 117,845,974 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,813,871 - 117,846,035 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710117,251,653 - 117,283,030 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610117,217,590 - 117,248,967 (-)NCBIMGSCv36mm8
Celera10119,752,445 - 119,762,526 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1066.32NCBI
Rap1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,308,922 - 55,342,217 (-)NCBIGRCr8
mRatBN7.2753,423,039 - 53,456,349 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl753,423,130 - 53,456,370 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx755,333,280 - 55,340,337 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0757,536,389 - 57,543,446 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0757,314,247 - 57,321,304 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0760,850,406 - 60,878,226 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,853,930 - 60,860,990 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0760,850,369 - 60,879,083 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4757,132,750 - 57,139,811 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1757,150,631 - 57,182,957 (-)NCBI
Celera750,197,811 - 50,204,871 (-)NCBICelera
Cytogenetic Map7q22NCBI
Rap1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545815,080,778 - 15,123,203 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545815,110,709 - 15,121,868 (+)NCBIChiLan1.0ChiLan1.0
RAP1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21076,628,927 - 76,679,160 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11276,625,344 - 76,675,630 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01266,122,212 - 66,172,450 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11268,919,369 - 68,955,650 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1268,942,053 - 68,955,649 (+)Ensemblpanpan1.1panPan2
RAP1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11010,805,359 - 10,816,839 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1010,805,357 - 10,815,575 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1010,700,667 - 10,750,121 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01010,891,820 - 10,941,270 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1010,891,815 - 10,941,253 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11010,759,466 - 10,808,891 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01011,005,977 - 11,055,507 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01011,128,484 - 11,177,911 (+)NCBIUU_Cfam_GSD_1.0
Rap1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494547,531,710 - 47,542,147 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365456,568,577 - 6,574,595 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365456,567,873 - 6,578,404 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAP1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl532,910,259 - 32,964,870 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1532,910,181 - 32,961,972 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2535,681,835 - 35,733,656 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rap1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624948623,527 - 664,000 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624948623,527 - 664,044 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 20 60
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000002328   ⟹   ENSCSAP00000000647
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1164,240,651 - 64,286,727 (+)Ensembl
RefSeq Acc Id: XM_008003959   ⟹   XP_008002150
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11164,240,501 - 64,290,515 (+)NCBI
Vero_WHO_p1.0NW_023666037181,414,337 - 181,465,060 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008003960   ⟹   XP_008002151
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11164,240,501 - 64,290,515 (+)NCBI
Vero_WHO_p1.0NW_023666037181,414,337 - 181,465,079 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008002150 (Get FASTA)   NCBI Sequence Viewer  
  XP_008002151 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000647
  ENSCSAP00000000647.1
  ENSCSAP00000018022.1
  ENSCSAP00000018065.1
RefSeq Acc Id: XP_008002150   ⟸   XM_008003959
- UniProtKB: A0A0D9SB26 (UniProtKB/TrEMBL),   A0A0D9SAY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002151   ⟸   XM_008003960
- UniProtKB: A0A0D9SB26 (UniProtKB/TrEMBL),   A0A0D9SAY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000647   ⟸   ENSCSAT00000002328


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004306 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSCSAG00000018483 UniProtKB/TrEMBL
  ENSCSAG00000018526 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002328 UniProtKB/TrEMBL
  ENSCSAT00000002328.1 UniProtKB/TrEMBL
  ENSCSAT00000018573.1 UniProtKB/TrEMBL
  ENSCSAT00000018616.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rap1 UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
KEGG Report csab:103215555 UniProtKB/TrEMBL
  csab:103238680 UniProtKB/TrEMBL
NCBI Gene RAP1B ENTREZGENE
PANTHER PTHR24070 UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAP-1B-RELATED UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9SAY3 ENTREZGENE, UniProtKB/TrEMBL
  A0A0D9SB26 ENTREZGENE, UniProtKB/TrEMBL