KCNH6 (potassium voltage-gated channel subfamily H member 6) - Rat Genome Database

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Gene: KCNH6 (potassium voltage-gated channel subfamily H member 6) Chlorocebus sabaeus
Analyze
Symbol: KCNH6
Name: potassium voltage-gated channel subfamily H member 6
RGD ID: 18422354
Description: ENCODES a protein that exhibits inward rectifier potassium channel activity (ortholog); protein-containing complex binding (ortholog); voltage-gated potassium channel activity (ortholog); INVOLVED IN potassium ion transport (ortholog); ASSOCIATED WITH glucose metabolism disease (ortholog); FOUND IN membrane (inferred); monoatomic ion channel complex (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11657,733,032 - 57,759,292 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1657,735,861 - 57,758,421 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607728,349,032 - 28,372,393 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNH6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11657,733,032 - 57,759,292 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1657,735,861 - 57,758,421 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607728,349,032 - 28,372,393 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
KCNH6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381763,523,358 - 63,548,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1763,523,334 - 63,548,977 (+)EnsemblGRCh38hg38GRCh38
GRCh371761,600,719 - 61,626,353 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361758,954,427 - 58,980,070 (+)NCBINCBI36Build 36hg18NCBI36
Build 341758,954,426 - 58,980,070NCBI
Celera1755,988,522 - 56,014,428 (+)NCBICelera
Cytogenetic Map17q23.3NCBI
HuRef1756,966,852 - 56,992,787 (+)NCBIHuRef
CHM1_11761,664,820 - 61,690,751 (+)NCBICHM1_1
T2T-CHM13v2.01764,393,673 - 64,419,606 (+)NCBIT2T-CHM13v2.0
Kcnh6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911105,898,871 - 105,926,421 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11105,898,950 - 105,925,375 (+)EnsemblGRCm39 Ensembl
GRCm3811106,008,044 - 106,035,595 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11106,008,124 - 106,034,549 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711105,869,517 - 105,895,378 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611105,824,293 - 105,850,154 (+)NCBIMGSCv36mm8
Celera11117,739,753 - 117,760,293 (+)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.87NCBI
Kcnh6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81091,449,025 - 91,471,012 (+)NCBIGRCr8
mRatBN7.21090,949,240 - 90,970,746 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1090,949,846 - 90,970,701 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1096,003,974 - 96,025,091 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01095,467,143 - 95,488,263 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01090,878,334 - 90,899,206 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01094,207,336 - 94,228,236 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1094,207,314 - 94,228,236 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01093,958,627 - 93,979,152 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,400,862 - 95,421,678 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11095,421,300 - 95,436,048 (+)NCBI
Celera1089,628,057 - 89,648,511 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Kcnh6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554788,243,949 - 8,263,336 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554788,242,953 - 8,263,369 (-)NCBIChiLan1.0ChiLan1.0
KCNH6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21979,694,849 - 79,720,406 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11784,512,403 - 84,537,957 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01757,603,039 - 57,626,964 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11762,749,240 - 62,772,544 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1762,749,216 - 62,772,544 (+)Ensemblpanpan1.1panPan2
KCNH6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1911,538,506 - 11,559,303 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl911,538,205 - 11,559,319 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha912,498,958 - 12,519,775 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0913,201,806 - 13,222,832 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl913,201,609 - 13,222,833 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1912,146,396 - 12,167,428 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0915,364,422 - 15,385,338 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0915,367,399 - 15,388,227 (-)NCBIUU_Cfam_GSD_1.0
Kcnh6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560214,974,734 - 14,996,783 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365414,197,751 - 4,220,076 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365414,197,826 - 4,219,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNH6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,353,867 - 15,374,858 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11215,352,765 - 15,374,763 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,340,202 - 15,361,582 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Kcnh6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248491,043,045 - 1,062,891 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248491,043,045 - 1,063,371 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KCNH6
450 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
74 34 17 31 31 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000001890   ⟹   ENSCSAP00000000224
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1657,735,861 - 57,758,421 (-)Ensembl
RefSeq Acc Id: XM_008012160   ⟹   XP_008010351
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11657,735,137 - 57,759,292 (-)NCBI
Vero_WHO_p1.0NW_02366607728,349,032 - 28,372,393 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008012164   ⟹   XP_008010355
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11657,735,839 - 57,759,292 (-)NCBI
Vero_WHO_p1.0NW_02366607728,349,032 - 28,372,393 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008010351 (Get FASTA)   NCBI Sequence Viewer  
  XP_008010355 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000224.1
RefSeq Acc Id: XP_008010351   ⟸   XM_008012160
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QV35 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008010355   ⟸   XM_008012164
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QV35 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000000224   ⟸   ENSCSAT00000001890


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003864 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001890.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1200.260 UniProtKB/TrEMBL
  1.10.287.70 UniProtKB/TrEMBL
  2.60.120.10 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro cNMP-bd-like UniProtKB/TrEMBL
  cNMP-bd_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_EAG/ELK/ERG UniProtKB/TrEMBL
  K_chnl_volt-dep_ERG UniProtKB/TrEMBL
  KCNH_channel UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
NCBI Gene KCNH6 ENTREZGENE
PANTHER PTHR10217:SF468 UniProtKB/TrEMBL
  VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL UniProtKB/TrEMBL
Pfam cNMP_binding UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
  PAS_9 UniProtKB/TrEMBL
PRINTS EAGCHANLFMLY UniProtKB/TrEMBL
  ERGCHANNEL UniProtKB/TrEMBL
PROSITE CNMP_BINDING_3 UniProtKB/TrEMBL
SMART cNMP UniProtKB/TrEMBL
Superfamily-SCOP SSF51206 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A0D9QV35 ENTREZGENE, UniProtKB/TrEMBL