PDE6G (phosphodiesterase 6G) - Rat Genome Database

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Gene: PDE6G (phosphodiesterase 6G) Chlorocebus sabaeus
Analyze
Symbol: PDE6G
Name: phosphodiesterase 6G
RGD ID: 18412858
Description: ENCODES a protein that exhibits spectrin binding (ortholog); INVOLVED IN positive regulation of epidermal growth factor receptor signaling pathway (ortholog); positive regulation of G protein-coupled receptor signaling pathway (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN altered visual phototransduction pathway; retinitis pigmentosa pathway; visual phototransduction pathway; ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); retinitis pigmentosa (ortholog); FOUND IN photoreceptor outer segment membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,582,249 - 73,594,139 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,583,362 - 73,585,414 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607744,988,012 - 44,990,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PDE6G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,582,249 - 73,594,139 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,583,362 - 73,585,414 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607744,988,012 - 44,990,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PDE6G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,650,459 - 81,663,127 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,650,459 - 81,663,112 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,617,489 - 79,630,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,227,894 - 77,234,038 (-)NCBINCBI36Build 36hg18NCBI36
Build 341777,227,654 - 77,233,971NCBI
Celera1776,262,515 - 76,268,615 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,063,689 - 75,069,807 (-)NCBIHuRef
CHM1_11779,703,710 - 79,709,828 (-)NCBICHM1_1
T2T-CHM13v2.01782,567,389 - 82,580,038 (-)NCBIT2T-CHM13v2.0
Pde6g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,338,433 - 120,344,326 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,338,431 - 120,344,326 (-)EnsemblGRCm39 Ensembl
GRCm3811120,447,607 - 120,453,500 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,447,605 - 120,453,500 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,308,924 - 120,314,797 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,263,700 - 120,269,573 (-)NCBIMGSCv36mm8
Celera11132,182,468 - 132,188,914 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.14NCBI
Pde6g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,219,849 - 106,224,496 (-)NCBIGRCr8
mRatBN7.210105,721,502 - 105,726,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,721,682 - 105,726,719 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,825,828 - 110,830,506 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,288,854 - 110,293,536 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,641,967 - 105,646,614 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,620,499 - 109,625,214 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,620,980 - 109,622,745 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,214,063 - 109,219,693 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10104,265,560 - 104,270,261 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Pde6g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,437,645 - 1,441,750 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,437,645 - 1,441,758 (+)NCBIChiLan1.0ChiLan1.0
PDE6G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,236,569 - 98,242,690 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,136,863 - 103,142,537 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,105,827 - 76,122,750 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11781,805,872 - 81,812,668 (-)NCBIpanpan1.1PanPan1.1panPan2
PDE6G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19525,123 - 529,406 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9526,577 - 529,526 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha91,128,757 - 1,131,569 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.091,120,090 - 1,122,902 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl91,120,090 - 1,123,175 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.191,144,991 - 1,147,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,271,603 - 1,274,415 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,350,610 - 1,353,422 (+)NCBIUU_Cfam_GSD_1.0
Pde6g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056021,144,561 - 1,148,614 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,263,333 - 5,267,476 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,263,345 - 5,267,240 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDE6G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,236,210 - 1,239,306 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,235,886 - 1,239,808 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pde6g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,597,860 - 10,601,811 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,597,722 - 10,602,784 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_008013253   ⟹   XP_008011444
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11673,582,249 - 73,594,139 (-)NCBI
Vero_WHO_p1.0NW_02366607744,988,012 - 44,990,720 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008011444 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015786.1
Reference Protein Sequences
RefSeq Acc Id: XP_008011444   ⟸   XM_008013253
- UniProtKB: A0A0D9S4J7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002251 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000270.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.1120.10 UniProtKB/TrEMBL
InterPro PDE6_gamma UniProtKB/TrEMBL
  PDE6_gamma_sf UniProtKB/TrEMBL
NCBI Gene PDE6G ENTREZGENE
PANTHER PTHR12122 UniProtKB/TrEMBL
  RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA UniProtKB/TrEMBL
Pfam PDE6_gamma UniProtKB/TrEMBL
PIRSF 35-cGMP_Pdiase_g UniProtKB/TrEMBL
UniProt A0A0D9S4J7 ENTREZGENE, UniProtKB/TrEMBL