DBNL (drebrin like) - Rat Genome Database

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Gene: DBNL (drebrin like) Chlorocebus sabaeus
Analyze
Symbol: DBNL
Name: drebrin like
RGD ID: 18405932
Description: ENCODES a protein that exhibits structural constituent of postsynaptic actin cytoskeleton (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); actin filament severing (ortholog); barbed-end actin filament capping (ortholog); ASSOCIATED WITH Dimauro Disease (ortholog); genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN dendrite (ortholog); glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: drebrin-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,610,196 - 14,627,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,608,571 - 14,627,321 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DBNL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,610,196 - 14,627,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,608,571 - 14,627,321 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DBNL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,044,702 - 44,069,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,044,640 - 44,069,456 (+)EnsemblGRCh38hg38GRCh38
GRCh37744,084,301 - 44,109,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,050,830 - 44,067,840 (+)NCBINCBI36Build 36hg18NCBI36
Celera744,182,185 - 44,199,260 (+)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,969,523 - 43,986,598 (+)NCBIHuRef
CHM1_1744,088,113 - 44,105,189 (+)NCBICHM1_1
T2T-CHM13v2.0744,203,197 - 44,227,954 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,123,733 - 44,140,805 (+)NCBI
Dbnl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,730,233 - 5,750,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,738,488 - 5,750,962 (+)EnsemblGRCm39 Ensembl
GRCm38115,788,483 - 5,800,980 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,788,488 - 5,800,962 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,688,486 - 5,700,983 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,688,533 - 5,700,965 (+)NCBIMGSCv36mm8
Celera116,278,834 - 6,291,141 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
Dbnl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,880,085 - 84,895,122 (+)NCBIGRCr8
mRatBN7.21480,666,115 - 80,681,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,068,401 - 85,083,685 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,308,505 - 86,323,788 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,757,826 - 82,773,110 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,029,335 - 86,044,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,721,144 - 86,736,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,450,448 - 86,481,863 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,469,592 - 86,484,067 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBICelera
Cytogenetic Map14q21NCBI
Dbnl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,912,827 - 7,924,787 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,912,827 - 7,924,373 (-)NCBIChiLan1.0ChiLan1.0
DBNL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,950,223 - 48,972,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,276,140 - 97,297,574 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,753,062 - 44,775,717 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,824,537 - 44,842,059 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,824,608 - 44,845,891 (+)Ensemblpanpan1.1panPan2
DBNL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha161,996,510 - 2,007,305 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,854,694 - 14,865,499 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,854,694 - 14,877,271 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,485,876 - 14,496,666 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,466,360 - 14,477,156 (-)NCBIUU_Cfam_GSD_1.0
Dbnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,795,888 - 99,809,337 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,007,672 - 19,020,361 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,007,630 - 19,021,068 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DBNL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,713,340 - 48,725,697 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,713,335 - 48,725,692 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,426,424 - 53,438,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Dbnl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,950,556 - 7,960,568 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,950,552 - 7,960,592 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 19 60
Low 1
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000013568   ⟹   ENSCSAP00000011561
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2114,608,571 - 14,627,321 (-)Ensembl
RefSeq Acc Id: XM_007981476   ⟹   XP_007979667
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12114,610,196 - 14,627,358 (-)NCBI
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007981477   ⟹   XP_007979668
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12114,610,196 - 14,627,363 (-)NCBI
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007981478   ⟹   XP_007979669
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12114,610,196 - 14,627,362 (-)NCBI
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007981479   ⟹   XP_007979670
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12114,610,196 - 14,627,361 (-)NCBI
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037988206   ⟹   XP_037844134
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBI
RefSeq Acc Id: XM_037988207   ⟹   XP_037844135
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBI
RefSeq Acc Id: XP_007979668   ⟸   XM_007981477
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007979669   ⟸   XM_007981478
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RSH2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007979670   ⟸   XM_007981479
- Peptide Label: isoform X6
RefSeq Acc Id: XP_007979667   ⟸   XM_007981476
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000011561   ⟸   ENSCSAT00000013568
RefSeq Acc Id: XP_037844134   ⟸   XM_037988206
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037844135   ⟸   XM_037988207
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015475 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013568.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ADF-H UniProtKB/TrEMBL
  ADF-H/Gelsolin-like_dom_sf UniProtKB/TrEMBL
  Drebrin-like_SH3 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene DBNL ENTREZGENE
PANTHER CORTACTIN AND DREBRIN UniProtKB/TrEMBL
  PTHR10829:SF12 UniProtKB/TrEMBL
Pfam Cofilin_ADF UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PROSITE ADF_H UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART ADF UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A0D9RSH2 ENTREZGENE, UniProtKB/TrEMBL