OSBPL8 (oxysterol binding protein like 8) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: OSBPL8 (oxysterol binding protein like 8) Chlorocebus sabaeus
Analyze
Symbol: OSBPL8
Name: oxysterol binding protein like 8
RGD ID: 18403038
Description: ENCODES a protein that exhibits phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylserine binding (ortholog); phosphatidylserine transfer activity (ortholog); INVOLVED IN fat cell differentiation (ortholog); negative regulation of cell migration (ortholog); negative regulation of sequestering of triglyceride (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 10 (ortholog); genetic disease (ortholog); FOUND IN cortical endoplasmic reticulum (ortholog); endoplasmic reticulum (ortholog); nuclear membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: oxysterol-binding protein-related protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11171,927,862 - 72,142,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1171,927,688 - 72,141,587 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
OSBPL8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11171,927,862 - 72,142,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1171,927,688 - 72,141,587 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
OSBPL8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381276,351,797 - 76,559,771 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1276,351,797 - 76,559,809 (-)EnsemblGRCh38hg38GRCh38
GRCh371276,745,577 - 76,953,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361275,269,708 - 75,477,720 (-)NCBINCBI36Build 36hg18NCBI36
Build 341275,248,047 - 75,456,057NCBI
Celera1276,411,526 - 76,618,915 (-)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1273,797,739 - 74,006,667 (-)NCBIHuRef
CHM1_11276,711,170 - 76,919,193 (-)NCBICHM1_1
T2T-CHM13v2.01276,329,717 - 76,537,711 (-)NCBIT2T-CHM13v2.0
Osbpl8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910111,000,663 - 111,133,110 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10111,000,613 - 111,133,110 (+)EnsemblGRCm39 Ensembl
GRCm3810111,164,742 - 111,297,249 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10111,164,752 - 111,297,249 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710110,601,858 - 110,734,303 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610110,568,912 - 110,701,357 (+)NCBIMGSCv36mm8
Celera10113,097,050 - 113,230,968 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1058.24NCBI
Osbpl8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,483,259 - 48,636,151 (+)NCBIGRCr8
mRatBN7.2746,596,944 - 46,749,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,596,983 - 46,749,888 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,496,671 - 48,649,451 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,699,816 - 50,852,600 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,477,574 - 50,630,354 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,878,906 - 54,030,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,878,610 - 54,027,892 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,888,262 - 54,039,874 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4750,308,713 - 50,313,369 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera743,400,573 - 43,550,915 (+)NCBICelera
Cytogenetic Map7q22NCBI
Osbpl8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540515,577,003 - 15,728,983 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540515,577,003 - 15,728,983 (-)NCBIChiLan1.0ChiLan1.0
OSBPL8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21084,386,348 - 84,594,367 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11284,382,738 - 84,590,772 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01273,870,094 - 74,078,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11276,720,276 - 76,927,919 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1276,720,276 - 76,820,830 (-)Ensemblpanpan1.1panPan2
OSBPL8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,339,385 - 19,441,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1519,142,987 - 19,637,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1519,824,481 - 19,967,789 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01519,678,921 - 19,822,002 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1519,678,364 - 19,822,062 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11519,279,309 - 19,422,482 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01519,337,403 - 19,480,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01519,465,384 - 19,608,478 (-)NCBIUU_Cfam_GSD_1.0
Osbpl8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494540,920,929 - 41,081,896 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365684,646,426 - 4,806,308 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365684,646,409 - 4,806,283 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSBPL8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl539,568,150 - 39,744,642 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1539,568,136 - 39,744,655 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2543,258,249 - 43,435,452 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Osbpl8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475021,569,352 - 21,757,660 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 16 60
Low 16 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008004074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008004084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037996778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037996779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037996780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037996781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037996783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037996784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000002053   ⟹   ENSCSAP00000000381
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1171,927,688 - 72,141,587 (-)Ensembl
RefSeq Acc Id: XM_008004079   ⟹   XP_008002270
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11171,927,862 - 72,142,631 (-)NCBI
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004080   ⟹   XP_008002271
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11171,927,862 - 72,003,180 (-)NCBI
Vero_WHO_p1.0NW_023666037173,544,061 - 173,620,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004082   ⟹   XP_008002273
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11171,927,862 - 72,142,630 (-)NCBI
Vero_WHO_p1.0NW_023666037173,404,093 - 173,620,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004084   ⟹   XP_008002275
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11171,927,862 - 72,142,398 (-)NCBI
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037996778   ⟹   XP_037852706
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBI
RefSeq Acc Id: XM_037996779   ⟹   XP_037852707
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBI
RefSeq Acc Id: XM_037996780   ⟹   XP_037852708
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBI
RefSeq Acc Id: XM_037996781   ⟹   XP_037852709
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037173,404,093 - 173,620,551 (+)NCBI
RefSeq Acc Id: XM_037996783   ⟹   XP_037852711
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037173,481,129 - 173,620,551 (+)NCBI
RefSeq Acc Id: XM_037996784   ⟹   XP_037852712
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037173,503,297 - 173,620,551 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008002270   ⟸   XM_008004079
- Peptide Label: isoform X3
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002273   ⟸   XM_008004082
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002275   ⟸   XM_008004084
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002271   ⟸   XM_008004080
- Peptide Label: isoform X5
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000381   ⟸   ENSCSAT00000002053
RefSeq Acc Id: XP_037852706   ⟸   XM_037996778
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037852707   ⟸   XM_037996779
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037852708   ⟸   XM_037996780
- Peptide Label: isoform X4
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037852709   ⟸   XM_037996781
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037852711   ⟸   XM_037996783
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037852712   ⟸   XM_037996784
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QVJ2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004024 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002053.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2720 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.40.160.120 UniProtKB/TrEMBL
  3.30.70.3490 UniProtKB/TrEMBL
InterPro OSBP_sf UniProtKB/TrEMBL
  Oxysterol-bd UniProtKB/TrEMBL
  Oxysterol-bd_CS UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report csab:103238761 UniProtKB/TrEMBL
NCBI Gene OSBPL8 ENTREZGENE
PANTHER OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 8 UniProtKB/TrEMBL
  PTHR10972 UniProtKB/TrEMBL
Pfam Oxysterol_BP UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PROSITE OSBP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF144000 UniProtKB/TrEMBL
UniProt A0A0D9QVJ2 ENTREZGENE, UniProtKB/TrEMBL