DPEP2 (dipeptidase 2) - Rat Genome Database

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Gene: DPEP2 (dipeptidase 2) Chlorocebus sabaeus
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Symbol: DPEP2
Name: dipeptidase 2
RGD ID: 18394875
Description: ENCODES a protein that exhibits dipeptidase activity (inferred); exopeptidase activity (inferred); metal ion binding (inferred); INVOLVED IN leukotriene D4 catabolic process (inferred); leukotriene metabolic process (inferred); proteolysis (inferred); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); FOUND IN membrane (inferred); side of membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,439,237 - 59,447,400 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,440,951 - 59,447,698 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,172,991 - 22,187,738 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DPEP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,439,237 - 59,447,400 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,440,951 - 59,447,698 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,172,991 - 22,187,738 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DPEP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,987,390 - 68,000,619 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,987,394 - 68,000,586 (-)EnsemblGRCh38hg38GRCh38
GRCh371668,021,293 - 68,034,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,578,798 - 66,590,857 (-)NCBINCBI36Build 36hg18NCBI36
Build 341666,578,800 - 66,590,857NCBI
Celera1652,529,750 - 52,541,821 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,894,885 - 53,907,048 (-)NCBIHuRef
CHM1_11669,429,363 - 69,441,488 (-)NCBICHM1_1
T2T-CHM13v2.01673,783,178 - 73,796,408 (-)NCBIT2T-CHM13v2.0
Dpep2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,711,577 - 106,732,658 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,711,577 - 106,723,055 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl8106,711,576 - 106,718,391 (-)EnsemblGRCm39 Ensembl
GRCm388105,984,945 - 106,006,026 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,984,944 - 105,991,759 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,984,945 - 105,996,423 (-)EnsemblGRCm38mm10GRCm38
MGSCv378108,508,957 - 108,520,323 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,874,186 - 108,885,552 (-)NCBIMGSCv36mm8
Celera8110,213,109 - 110,224,474 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.07NCBI
Dpep2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,795,322 - 50,806,320 (-)NCBIGRCr8
mRatBN7.21933,883,557 - 33,896,487 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,885,478 - 33,891,954 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,701,008 - 40,707,443 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,354,322 - 41,360,757 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,653,038 - 43,659,469 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,964,098 - 37,975,154 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,964,105 - 37,970,537 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,831,084 - 48,851,920 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,832,224 - 35,838,659 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,837,105 - 35,843,540 (-)NCBI
Celera1933,313,021 - 33,319,456 (-)NCBICelera
Cytogenetic Map19q12NCBI
DPEP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,510,359 - 77,526,862 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,421,784 - 83,438,196 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,328,281 - 48,341,510 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,715,805 - 67,729,164 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,715,805 - 67,729,164 (-)Ensemblpanpan1.1panPan2
DPEP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,506,635 - 81,511,282 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,506,330 - 81,511,175 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,495,291 - 81,501,196 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0581,940,443 - 81,946,361 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl581,940,034 - 81,946,254 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1581,766,906 - 81,772,812 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,449,218 - 81,455,110 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,091,144 - 82,097,061 (+)NCBIUU_Cfam_GSD_1.0
DPEP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,593,546 - 28,599,051 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,593,542 - 28,599,076 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2626,020,128 - 26,025,817 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20
Low 34 23
Below cutoff 2 37

Sequence


Ensembl Acc Id: ENSCSAT00000002066   ⟹   ENSCSAP00000000394
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl559,440,951 - 59,447,698 (+)Ensembl
RefSeq Acc Id: XM_007993895   ⟹   XP_007992086
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1559,439,860 - 59,447,400 (+)NCBI
Vero_WHO_p1.0NW_02366604722,172,991 - 22,187,738 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007993896   ⟹   XP_007992087
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1559,439,237 - 59,447,400 (+)NCBI
Vero_WHO_p1.0NW_02366604722,172,991 - 22,187,738 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007993898   ⟹   XP_007992089
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1559,439,860 - 59,447,400 (+)NCBI
Vero_WHO_p1.0NW_02366604722,172,991 - 22,187,738 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038007999   ⟹   XP_037863927
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604722,172,991 - 22,187,738 (+)NCBI
RefSeq Acc Id: XM_038008000   ⟹   XP_037863928
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604722,172,991 - 22,187,738 (+)NCBI
RefSeq Acc Id: XP_007992087   ⟸   XM_007993896
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QVK5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992089   ⟸   XM_007993898
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007992086   ⟸   XM_007993895
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QVK5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000000394   ⟸   ENSCSAT00000002066
RefSeq Acc Id: XP_037863927   ⟸   XM_038007999
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037863928   ⟸   XM_038008000
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004036 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002066.1 UniProtKB/TrEMBL
Gene3D-CATH Metal-dependent hydrolases UniProtKB/TrEMBL
InterPro Dipep_AS UniProtKB/TrEMBL
  Metal_Hydrolase UniProtKB/TrEMBL
  Pept_M19 UniProtKB/TrEMBL
KEGG Report csab:103233247 UniProtKB/TrEMBL
NCBI Gene DPEP2 ENTREZGENE
PANTHER DIPEPTIDASE 2 UniProtKB/TrEMBL
  PTHR10443 UniProtKB/TrEMBL
Pfam Peptidase_M19 UniProtKB/TrEMBL
PROSITE RENAL_DIPEPTIDASE_1 UniProtKB/TrEMBL
  RENAL_DIPEPTIDASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF51556 UniProtKB/TrEMBL
UniProt A0A0D9QVK5 ENTREZGENE, UniProtKB/TrEMBL