RAB40B (RAB40B, member RAS oncogene family) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: RAB40B (RAB40B, member RAS oncogene family) Chlorocebus sabaeus
Analyze
Symbol: RAB40B
Name: RAB40B, member RAS oncogene family
RGD ID: 18384703
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN cellular detoxification (inferred); intracellular signal transduction (inferred); protein localization to plasma membrane (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN endosome (inferred); membrane (inferred); nuclear envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-40B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11674,558,970 - 74,595,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1674,559,763 - 74,595,841 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607746,199,797 - 46,237,650 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAB40B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11674,558,970 - 74,595,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1674,559,763 - 74,595,841 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607746,199,797 - 46,237,650 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAB40B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381782,654,973 - 82,698,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1782,654,973 - 82,698,698 (-)EnsemblGRCh38hg38GRCh38
GRCh371780,612,849 - 80,656,574 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361778,208,238 - 78,249,802 (-)NCBINCBI36Build 36hg18NCBI36
Build 341778,208,237 - 78,249,802NCBI
Celera1777,209,247 - 77,250,771 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1776,014,951 - 76,056,442 (-)NCBIHuRef
CHM1_11780,701,145 - 80,742,977 (-)NCBICHM1_1
T2T-CHM13v2.01783,529,323 - 83,573,130 (-)NCBIT2T-CHM13v2.0
Rab40b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911121,246,951 - 121,279,080 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11121,246,951 - 121,279,077 (-)EnsemblGRCm39 Ensembl
GRCm3811121,356,121 - 121,388,251 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11121,356,125 - 121,388,251 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711121,217,435 - 121,249,565 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611121,172,215 - 121,204,335 (-)NCBIMGSCv36mm8
Celera11133,093,587 - 133,125,778 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1185.28NCBI
Rab40b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810107,129,801 - 107,157,375 (-)NCBIGRCr8
mRatBN7.210106,631,514 - 106,659,090 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10106,631,514 - 106,659,090 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10111,733,874 - 111,761,463 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010111,196,923 - 111,224,513 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010106,551,924 - 106,579,498 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010110,557,798 - 110,585,424 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10110,557,729 - 110,585,376 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010110,143,366 - 110,171,085 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410110,590,703 - 110,618,223 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110110,605,202 - 110,632,641 (-)NCBI
Celera10105,169,974 - 105,197,417 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Rab40b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955506479,516 - 512,362 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955506480,236 - 509,038 (+)NCBIChiLan1.0ChiLan1.0
RAB40B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21999,196,529 - 99,241,990 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117104,100,556 - 104,145,357 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1782,872,403 - 82,902,803 (-)Ensemblpanpan1.1panPan2
RAB40B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha9359,952 - 379,474 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.09351,762 - 371,277 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9351,795 - 371,277 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.19345,847 - 365,366 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.09507,101 - 526,608 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.09582,386 - 601,900 (+)NCBIUU_Cfam_GSD_1.0
RAB40B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl12493,315 - 516,962 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.112492,298 - 516,965 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.212221,054 - 245,023 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rab40b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480111,363,537 - 11,389,183 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480111,363,539 - 11,389,201 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 60
Low 18
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008013378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000000111   ⟹   ENSCSAP00000015941
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1674,559,763 - 74,595,841 (-)Ensembl
RefSeq Acc Id: XM_008013378   ⟹   XP_008011569
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11674,558,970 - 74,595,967 (-)NCBI
Vero_WHO_p1.0NW_02366607746,199,797 - 46,237,650 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008011569 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015941
  ENSCSAP00000015941.1
Reference Protein Sequences
RefSeq Acc Id: XP_008011569   ⟸   XM_008013378
- UniProtKB: A0A0D9S502 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015941   ⟸   ENSCSAT00000000111


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002098 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000111.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103243778 UniProtKB/TrEMBL
NCBI Gene RAB40B ENTREZGENE
PANTHER LD44762P UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-40B UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9S502 ENTREZGENE, UniProtKB/TrEMBL