CPM (carboxypeptidase M) - Rat Genome Database

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Gene: CPM (carboxypeptidase M) Chlorocebus sabaeus
Analyze
Symbol: CPM
Name: carboxypeptidase M
RGD ID: 18380698
Description: ENCODES a protein that exhibits metallocarboxypeptidase activity (inferred); zinc ion binding (inferred); INVOLVED IN peptide metabolic process (inferred); protein processing (inferred); proteolysis (inferred); PARTICIPATES IN kallikrein-kinin cascade pathway; ASSOCIATED WITH endometriosis (ortholog); genetic disease (ortholog); silicosis (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11164,475,842 - 64,556,877 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1164,478,106 - 64,556,278 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037181,146,800 - 181,226,452 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CPM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11164,475,842 - 64,556,877 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1164,478,106 - 64,556,278 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037181,146,800 - 181,226,452 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CPM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381268,842,197 - 68,963,469 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1268,842,197 - 68,971,570 (-)EnsemblGRCh38hg38GRCh38
GRCh371269,244,955 - 69,357,249 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361267,531,222 - 67,643,287 (-)NCBINCBI36Build 36hg18NCBI36
Build 341267,531,224 - 67,613,246NCBI
Celera1268,908,769 - 69,020,812 (-)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1266,295,534 - 66,407,539 (-)NCBIHuRef
CHM1_11269,213,548 - 69,325,636 (-)NCBICHM1_1
T2T-CHM13v2.01268,821,776 - 68,943,048 (-)NCBIT2T-CHM13v2.0
Cpm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910117,465,405 - 117,523,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10117,465,405 - 117,523,257 (+)EnsemblGRCm39 Ensembl
GRCm3810117,629,500 - 117,687,352 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,629,500 - 117,687,352 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710117,066,556 - 117,124,408 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610117,032,084 - 117,090,343 (+)NCBIMGSCv36mm8
Celera10119,567,183 - 119,625,204 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1066.19NCBI
Cpm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,111,599 - 55,172,114 (+)NCBIGRCr8
mRatBN7.2753,225,647 - 53,286,220 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl753,225,696 - 53,286,220 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx755,132,408 - 55,192,931 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0757,335,524 - 57,396,045 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0757,113,401 - 57,173,922 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0760,654,350 - 60,714,620 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,654,350 - 60,714,620 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0760,654,168 - 60,714,583 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,931,920 - 56,992,248 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1756,952,660 - 57,008,965 (+)NCBI
Celera749,997,342 - 50,057,583 (+)NCBICelera
Cytogenetic Map7q22NCBI
Cpm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545815,296,783 - 15,360,753 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545815,296,783 - 15,360,753 (-)NCBIChiLan1.0ChiLan1.0
CPM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21076,868,706 - 76,951,136 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11276,858,348 - 76,947,533 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01266,367,023 - 66,445,801 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11269,147,579 - 69,225,596 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1269,147,579 - 69,225,283 (-)Ensemblpanpan1.1panPan2
CPM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11010,968,830 - 10,999,887 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1010,900,937 - 10,974,726 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01011,092,652 - 11,165,951 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1011,085,709 - 11,165,621 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11010,960,274 - 11,033,677 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01011,206,263 - 11,279,965 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01011,328,446 - 11,402,120 (-)NCBIUU_Cfam_GSD_1.0
Cpm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494547,306,534 - 47,371,888 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365456,737,851 - 6,803,662 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365456,739,658 - 6,803,501 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl533,151,388 - 33,264,317 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1533,170,094 - 33,264,362 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Cpm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624948369,612 - 437,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624948369,237 - 441,371 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 2
Low 34 18 60
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000002268   ⟹   ENSCSAP00000000594
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1164,478,106 - 64,556,278 (-)Ensembl
RefSeq Acc Id: XM_008003974   ⟹   XP_008002165
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11164,475,842 - 64,556,344 (-)NCBI
Vero_WHO_p1.0NW_023666037181,146,800 - 181,226,452 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008002165 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000594.1
Reference Protein Sequences
RefSeq Acc Id: XP_008002165   ⟸   XM_008003974
- UniProtKB: A0A0D9QW55 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000594   ⟸   ENSCSAT00000002268


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004238 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002268.1 UniProtKB/TrEMBL
Gene3D-CATH Carboxypeptidase-like, regulatory domain UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CarboxyPept-like_regulatory UniProtKB/TrEMBL
  CPM_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
KEGG Report csab:103238691 UniProtKB/TrEMBL
NCBI Gene CPM ENTREZGENE
PANTHER CARBOXYPEPTIDASE M UniProtKB/TrEMBL
  PROTEASE M14 CARBOXYPEPTIDASE UniProtKB/TrEMBL
Pfam CarboxypepD_reg UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
SMART Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP SSF49464 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A0D9QW55 ENTREZGENE, UniProtKB/TrEMBL