GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A) - Rat Genome Database

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Gene: GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A) Chlorocebus sabaeus
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Symbol: GRIN3A
Name: glutamate ionotropic receptor NMDA type subunit 3A
RGD ID: 18379314
Description: ENCODES a protein that exhibits glutamate-gated receptor activity (ortholog); NMDA glutamate receptor activity (ortholog); protein phosphatase 2A binding (ortholog); INVOLVED IN calcium ion transport (ortholog); dendrite development (ortholog); ionotropic glutamate receptor signaling pathway (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH fructose-1,6-bisphosphatase deficiency (ortholog); hereditary fructose intolerance syndrome (ortholog); impotence (ortholog); FOUND IN cytoplasm (ortholog); glutamatergic synapse (ortholog); monoatomic ion channel complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate receptor ionotropic, NMDA 3A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11237,700,311 - 37,865,390 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1237,701,039 - 37,867,041 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660354,693,852 - 4,858,752 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
excitatory synaptic transmission pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
methadone pharmacokinetics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GRIN3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11237,700,311 - 37,865,390 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1237,701,039 - 37,867,041 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660354,693,852 - 4,858,752 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GRIN3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389101,569,352 - 101,738,647 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9101,569,352 - 101,738,647 (-)EnsemblGRCh38hg38GRCh38
GRCh379104,331,634 - 104,500,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369103,371,456 - 103,540,683 (-)NCBINCBI36Build 36hg18NCBI36
Build 349101,411,189 - 101,580,417NCBI
Celera974,845,889 - 75,014,334 (-)NCBICelera
Cytogenetic Map9q31.1NCBI
HuRef973,932,382 - 74,100,688 (-)NCBIHuRef
CHM1_19104,478,039 - 104,647,164 (-)NCBICHM1_1
T2T-CHM13v2.09113,744,124 - 113,912,649 (-)NCBIT2T-CHM13v2.0
Grin3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39449,661,611 - 49,846,023 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl449,661,611 - 49,845,744 (-)EnsemblGRCm39 Ensembl
GRCm38449,661,611 - 49,846,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl449,661,611 - 49,845,744 (-)EnsemblGRCm38mm10GRCm38
MGSCv37449,678,098 - 49,857,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera449,693,525 - 49,874,264 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.72NCBI
Grin3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8568,802,333 - 69,001,880 (-)NCBIGRCr8
mRatBN7.2564,006,847 - 64,206,408 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl564,009,980 - 64,206,085 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx565,943,276 - 66,142,503 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0567,762,618 - 67,961,860 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0567,731,985 - 67,931,195 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0564,928,620 - 65,073,012 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl564,928,620 - 65,073,012 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0569,420,058 - 69,564,696 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4566,406,451 - 66,602,353 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1566,411,563 - 66,607,247 (-)NCBI
Celera563,404,358 - 63,599,048 (+)NCBICelera
Cytogenetic Map5q22NCBI
Grin3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541924,104,820 - 24,273,113 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541924,105,360 - 24,272,533 (+)NCBIChiLan1.0ChiLan1.0
GRIN3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21137,628,485 - 37,797,704 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1937,630,856 - 37,800,076 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0972,773,866 - 72,943,790 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19100,767,715 - 100,936,352 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9100,767,715 - 100,941,323 (-)Ensemblpanpan1.1panPan2
GRIN3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11158,271,808 - 58,421,887 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1158,273,377 - 58,421,761 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1156,716,312 - 56,866,073 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01159,411,203 - 59,557,777 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1159,411,203 - 59,557,626 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11157,917,161 - 58,067,281 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01157,930,109 - 58,080,617 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01158,627,851 - 58,778,332 (-)NCBIUU_Cfam_GSD_1.0
Grin3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947173,173,201 - 173,337,402 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365249,720,767 - 9,885,120 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365249,720,777 - 9,884,984 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIN3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1243,259,495 - 243,415,590 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11243,263,202 - 243,416,739 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21271,873,962 - 272,030,759 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Grin3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247589,579,752 - 9,756,525 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247589,579,750 - 9,756,396 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000009323   ⟹   ENSCSAP00000007444
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1237,701,039 - 37,867,041 (+)Ensembl
RefSeq Acc Id: XM_007968548   ⟹   XP_007966739
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11237,700,311 - 37,865,390 (+)NCBI
Vero_WHO_p1.0NW_0236660354,693,852 - 4,858,752 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007966739 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007444.1
RefSeq Acc Id: XP_007966739   ⟸   XM_007968548
- UniProtKB: A0A0D9RFQ5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000007444   ⟸   ENSCSAT00000009323


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011247 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009323.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2300 UniProtKB/TrEMBL
  Periplasmic binding protein-like II UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  Glu/Gly-bd UniProtKB/TrEMBL
  Iono_rcpt_met UniProtKB/TrEMBL
  Ionotropic_Glu_rcpt UniProtKB/TrEMBL
  Iontro_rcpt UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene GRIN3A ENTREZGENE
PANTHER GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3A UniProtKB/TrEMBL
  IONOTROPIC GLUTAMATE RECEPTOR UniProtKB/TrEMBL
Pfam ANF_receptor UniProtKB/TrEMBL
  Lig_chan UniProtKB/TrEMBL
  Lig_chan-Glu_bd UniProtKB/TrEMBL
PRINTS NMDARECEPTOR UniProtKB/TrEMBL
SMART Lig_chan-Glu_bd UniProtKB/TrEMBL
  PBPe UniProtKB/TrEMBL
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/TrEMBL
  SSF53822 UniProtKB/TrEMBL
UniProt A0A0D9RFQ5 ENTREZGENE, UniProtKB/TrEMBL