BMT2 (base methyltransferase of 25S rRNA 2 homolog) - Rat Genome Database

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Gene: BMT2 (base methyltransferase of 25S rRNA 2 homolog) Chlorocebus sabaeus
Analyze
Symbol: BMT2
Name: base methyltransferase of 25S rRNA 2 homolog
RGD ID: 18372553
Description: ENCODES a protein that exhibits methyltransferase activity (inferred); S-adenosyl-L-methionine binding (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to methionine (inferred); methylation (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); pleomorphic xanthoastrocytoma (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable methyltransferase BTM2 homolog; S-adenosylmethionine sensor upstream of mTORC1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12181,618,346 - 81,733,618 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2181,618,094 - 81,733,709 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604222,059,990 - 22,184,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
BMT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12181,618,346 - 81,733,618 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2181,618,094 - 81,733,709 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604222,059,990 - 22,184,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BMT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387112,819,147 - 112,939,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7112,819,147 - 112,939,875 (-)EnsemblGRCh38hg38GRCh38
GRCh377112,459,202 - 112,579,930 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367112,246,438 - 112,367,168 (-)NCBINCBI36Build 36hg18NCBI36
Celera7107,271,822 - 107,392,595 (-)NCBICelera
Cytogenetic Map7q31.1NCBI
HuRef7106,827,013 - 106,948,026 (-)NCBIHuRef
CHM1_17112,392,867 - 112,513,647 (-)NCBICHM1_1
T2T-CHM13v2.07114,138,029 - 114,258,806 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27111,827,660 - 111,948,430 (-)NCBI
Bmt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39613,625,674 - 13,677,965 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl613,625,672 - 13,677,965 (-)EnsemblGRCm39 Ensembl
GRCm38613,625,675 - 13,677,966 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl613,625,673 - 13,677,966 (-)EnsemblGRCm38mm10GRCm38
MGSCv37613,575,675 - 13,627,966 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36613,575,937 - 13,627,966 (-)NCBIMGSCv36mm8
Celera613,717,757 - 13,770,039 (-)NCBICelera
Cytogenetic Map6A1NCBI
cM Map65.69NCBI
Bmt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8442,847,720 - 42,911,546 (-)NCBIGRCr8
mRatBN7.2441,881,630 - 41,945,472 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl441,879,993 - 41,945,539 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx446,857,424 - 46,921,263 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0442,778,434 - 42,842,275 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0441,187,135 - 41,250,978 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0440,064,131 - 40,136,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl440,063,932 - 40,136,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0439,891,453 - 39,963,623 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4439,060,833 - 39,128,205 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera437,230,510 - 37,293,968 (-)NCBICelera
Cytogenetic Map4q21NCBI
Bmt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543219,046,121 - 19,107,753 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543219,046,121 - 19,107,178 (-)NCBIChiLan1.0ChiLan1.0
BMT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26149,650,712 - 149,769,964 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan171,660,967 - 1,780,071 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07104,786,390 - 104,905,357 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17117,488,026 - 117,607,033 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7117,488,026 - 117,607,033 (-)Ensemblpanpan1.1panPan2
BMT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11452,363,629 - 52,456,440 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1452,366,219 - 52,456,404 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1451,822,397 - 51,915,239 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01452,392,619 - 52,485,414 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1452,392,619 - 52,485,896 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11452,432,652 - 52,525,187 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01452,111,544 - 52,203,910 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01452,489,856 - 52,582,458 (-)NCBIUU_Cfam_GSD_1.0
Bmt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511841,030,784 - 41,111,480 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365895,578,519 - 5,659,400 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365895,578,566 - 5,657,093 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1832,798,290 - 32,900,764 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11832,798,278 - 32,900,769 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21835,595,673 - 35,646,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Bmt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248276,434,483 - 6,509,446 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248276,434,583 - 6,509,481 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 11 34
Low 25 20 26
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007982630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000009188   ⟹   ENSCSAP00000007314
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2181,618,094 - 81,733,709 (-)Ensembl
RefSeq Acc Id: XM_007982630   ⟹   XP_007980821
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12181,618,346 - 81,733,618 (-)NCBI
Vero_WHO_p1.0NW_02366604222,059,990 - 22,184,770 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007980821 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007314
  ENSCSAP00000007314.1
Reference Protein Sequences
RefSeq Acc Id: XP_007980821   ⟸   XM_007982630
- UniProtKB: A0A0D9RFC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007314   ⟸   ENSCSAT00000009188


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011101 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009188.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro Bmt2/SAMTOR UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
KEGG Report csab:103226755 UniProtKB/TrEMBL
NCBI Gene BMT2 ENTREZGENE
PANTHER PTHR21008 UniProtKB/TrEMBL
  S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 UniProtKB/TrEMBL
Pfam Bmt2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0D9RFC5 ENTREZGENE, UniProtKB/TrEMBL