DMXL2 (Dmx like 2) - Rat Genome Database

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Gene: DMXL2 (Dmx like 2) Chlorocebus sabaeus
Analyze
Symbol: DMXL2
Name: Dmx like 2
RGD ID: 18365234
Description: ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN brain development (ortholog); chemical synaptic transmission (ortholog); corpus callosum development (ortholog); ASSOCIATED WITH amenorrhea (ortholog); autism spectrum disorder (ortholog); autosomal dominant nonsyndromic deafness 71 (ortholog); FOUND IN neuronal dense core vesicle (ortholog); synaptic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dmX-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12631,750,419 - 31,922,022 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2631,750,403 - 31,922,208 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048109,282,977 - 109,463,900 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DMXL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12631,750,419 - 31,922,022 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2631,750,403 - 31,922,208 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048109,282,977 - 109,463,900 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DMXL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381551,447,791 - 51,622,771 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1551,447,711 - 51,622,833 (-)EnsemblGRCh38hg38GRCh38
GRCh371551,739,988 - 51,914,968 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361549,527,229 - 49,702,259 (-)NCBINCBI36Build 36hg18NCBI36
Build 341549,528,180 - 49,702,241NCBI
Celera1528,633,317 - 28,808,362 (-)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1528,569,985 - 28,745,024 (-)NCBIHuRef
CHM1_11551,858,027 - 52,033,010 (-)NCBICHM1_1
T2T-CHM13v2.01549,255,566 - 49,430,224 (-)NCBIT2T-CHM13v2.0
Dmxl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39954,272,442 - 54,409,150 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl954,272,442 - 54,408,910 (-)EnsemblGRCm39 Ensembl
GRCm38954,365,158 - 54,501,866 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl954,365,158 - 54,501,626 (-)EnsemblGRCm38mm10GRCm38
MGSCv37954,212,965 - 54,349,433 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36954,163,295 - 54,300,216 (-)NCBIMGSCv36mm8
Celera951,607,730 - 51,744,103 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map929.58NCBI
Dmxl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8863,637,314 - 63,803,911 (-)NCBIGRCr8
mRatBN7.2854,741,164 - 54,884,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl854,741,160 - 54,885,161 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0858,932,575 - 59,077,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl858,932,580 - 59,077,690 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0857,508,009 - 57,658,319 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4857,857,243 - 58,047,495 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera854,231,921 - 54,355,025 (-)NCBICelera
Cytogenetic Map8q24NCBI
Dmxl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554092,934,740 - 3,089,703 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554092,934,755 - 3,089,572 (+)NCBIChiLan1.0ChiLan1.0
DMXL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21640,681,331 - 40,853,531 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11544,861,796 - 45,033,992 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01530,386,009 - 30,557,976 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11548,719,144 - 48,890,793 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1548,719,150 - 48,890,708 (-)Ensemblpanpan1.1panPan2
DMXL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13017,156,077 - 17,308,641 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3017,156,791 - 17,308,803 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3017,082,692 - 17,235,590 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03017,301,686 - 17,454,656 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3017,301,699 - 17,454,485 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13017,223,785 - 17,376,247 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03017,341,368 - 17,495,042 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03017,447,910 - 17,600,883 (-)NCBIUU_Cfam_GSD_1.0
Dmxl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864095,482,807 - 95,635,550 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647113,329,622 - 13,483,937 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647113,330,870 - 13,483,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DMXL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1120,138,336 - 120,298,586 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11120,138,249 - 120,298,603 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21133,338,228 - 133,450,265 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Dmxl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247318,702,137 - 8,842,653 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247318,702,288 - 8,843,807 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 23 2 60
Low 13 18
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000009378   ⟹   ENSCSAP00000007497
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2631,750,403 - 31,922,208 (+)Ensembl
RefSeq Acc Id: XM_008016603   ⟹   XP_008014794
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12631,750,419 - 31,922,022 (+)NCBI
Vero_WHO_p1.0NW_023666048109,282,977 - 109,463,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016604   ⟹   XP_008014795
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12631,750,419 - 31,922,022 (+)NCBI
Vero_WHO_p1.0NW_023666048109,282,977 - 109,463,835 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016605   ⟹   XP_008014796
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12631,750,419 - 31,922,022 (+)NCBI
Vero_WHO_p1.0NW_023666048109,283,038 - 109,463,835 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016606   ⟹   XP_008014797
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12631,750,419 - 31,922,022 (+)NCBI
Vero_WHO_p1.0NW_023666048109,283,038 - 109,463,835 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005244325
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666048109,282,977 - 109,463,900 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008014794 (Get FASTA)   NCBI Sequence Viewer  
  XP_008014795 (Get FASTA)   NCBI Sequence Viewer  
  XP_008014796 (Get FASTA)   NCBI Sequence Viewer  
  XP_008014797 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007497.1
Reference Protein Sequences
RefSeq Acc Id: XP_008014794   ⟸   XM_008016603
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RFV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008014796   ⟸   XM_008016605
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RFV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008014795   ⟸   XM_008016604
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RFV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008014797   ⟸   XM_008016606
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RFV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007497   ⟸   ENSCSAT00000009378


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011292 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009378.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Rav1p_C UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103245624 UniProtKB/TrEMBL
NCBI Gene DMXL2 ENTREZGENE
PANTHER DMX-LIKE PROTEIN 2 UniProtKB/TrEMBL
  RABCONNECTIN-RELATED UniProtKB/TrEMBL
Pfam Rav1p_C UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9RFV8 ENTREZGENE, UniProtKB/TrEMBL