ATP11A (ATPase phospholipid transporting 11A) - Rat Genome Database

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Gene: ATP11A (ATPase phospholipid transporting 11A) Chlorocebus sabaeus
Analyze
Symbol: ATP11A
Name: ATPase phospholipid transporting 11A
RGD ID: 18363293
Description: ENCODES a protein that exhibits phosphatidylethanolamine flippase activity (ortholog); phosphatidylserine flippase activity (ortholog); INVOLVED IN in utero embryonic development (ortholog); positive regulation of myotube differentiation (ortholog); regulation of membrane lipid distribution (ortholog); ASSOCIATED WITH Autosomal Dominant Auditory Neuropathy 2 (ortholog); autosomal dominant nonsyndromic deafness 33 (ortholog); Autosomal Dominant Nonsyndromic Deafness 84 (ortholog); FOUND IN Golgi apparatus (ortholog); intracellular membrane-bounded organelle (ortholog); phospholipid-translocating ATPase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable phospholipid-transporting ATPase IH
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1390,709,348 - 90,893,610 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl390,709,298 - 90,887,360 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604647,630,891 - 47,883,537 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ATP11A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1390,709,348 - 90,893,610 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl390,709,298 - 90,887,360 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604647,630,891 - 47,883,537 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ATP11A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813112,690,038 - 112,887,168 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13112,690,038 - 112,887,168 (+)EnsemblGRCh38hg38GRCh38
GRCh3713113,344,352 - 113,541,482 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,392,644 - 112,589,483 (+)NCBINCBI36Build 36hg18NCBI36
Build 3413112,392,643 - 112,589,467NCBI
Celera1394,169,962 - 94,366,346 (+)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1393,786,589 - 93,982,360 (+)NCBIHuRef
CHM1_113113,313,695 - 113,510,486 (+)NCBICHM1_1
T2T-CHM13v2.013111,938,073 - 112,137,143 (+)NCBIT2T-CHM13v2.0
Atp11a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39812,807,016 - 12,918,728 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl812,807,014 - 12,918,728 (+)EnsemblGRCm39 Ensembl
GRCm38812,757,016 - 12,868,728 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl812,757,014 - 12,868,728 (+)EnsemblGRCm38mm10GRCm38
MGSCv37812,757,016 - 12,868,728 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36812,757,201 - 12,865,150 (+)NCBIMGSCv36mm8
Celera812,924,468 - 13,036,528 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
Atp11a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81683,359,884 - 83,469,807 (-)NCBIGRCr8
mRatBN7.21676,657,752 - 76,767,640 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1676,657,752 - 76,767,640 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,938,281 - 82,048,154 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01685,390,878 - 85,500,747 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01680,640,040 - 80,750,901 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01681,990,340 - 82,100,222 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,990,340 - 82,100,222 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01681,476,069 - 81,586,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,514,979 - 81,624,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11681,501,632 - 81,609,375 (-)NCBI
Celera1674,464,012 - 74,573,797 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
Atp11a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404820,263 - 912,351 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955404820,788 - 906,531 (-)NCBIChiLan1.0ChiLan1.0
ATP11A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214114,183,918 - 114,379,070 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113112,869,802 - 113,063,779 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01393,822,102 - 94,016,837 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113112,999,645 - 113,096,015 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13112,997,252 - 113,091,167 (+)Ensemblpanpan1.1panPan2
ATP11A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12260,302,098 - 60,431,070 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2260,302,309 - 60,428,080 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2260,015,066 - 60,143,830 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02260,929,759 - 61,058,315 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2260,929,048 - 61,056,821 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12260,428,554 - 60,555,405 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02260,424,306 - 60,552,852 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02260,458,948 - 60,587,815 (+)NCBIUU_Cfam_GSD_1.0
Atp11a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945195,201,759 - 195,286,188 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936472669,155 - 730,035 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936472665,967 - 750,396 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP11A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,293,469 - 78,402,083 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,292,734 - 78,402,108 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Atp11a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624793903,847 - 998,436 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624793904,320 - 998,413 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 13 35
Low 23 20 25
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015547   ⟹   ENSCSAP00000013485
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl390,709,298 - 90,887,360 (+)Ensembl
RefSeq Acc Id: XM_007960940   ⟹   XP_007959131
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1390,709,348 - 90,893,610 (+)NCBI
Vero_WHO_p1.0NW_02366604647,630,891 - 47,883,537 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007960941   ⟹   XP_007959132
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1390,709,348 - 90,893,610 (+)NCBI
Vero_WHO_p1.0NW_02366604647,630,891 - 47,883,537 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007960942   ⟹   XP_007959133
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1390,709,348 - 90,890,988 (+)NCBI
Vero_WHO_p1.0NW_02366604647,630,891 - 47,878,630 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038007904   ⟹   XP_037863832
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604647,630,891 - 47,883,537 (+)NCBI
RefSeq Acc Id: XM_038007905   ⟹   XP_037863833
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604647,630,891 - 47,878,629 (+)NCBI
RefSeq Acc Id: XM_038007906   ⟹   XP_037863834
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604647,630,891 - 47,878,628 (+)NCBI
RefSeq Acc Id: XM_038007907   ⟹   XP_037863835
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604647,630,891 - 47,878,860 (+)NCBI
RefSeq Acc Id: XM_038007908   ⟹   XP_037863836
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604647,630,891 - 47,878,616 (+)NCBI
RefSeq Acc Id: XM_038007909   ⟹   XP_037863837
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604647,630,891 - 47,878,686 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007959131   ⟸   XM_007960940
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007959132   ⟸   XM_007960941
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007959133   ⟸   XM_007960942
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RXZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013485   ⟸   ENSCSAT00000015547
RefSeq Acc Id: XP_037863832   ⟸   XM_038007904
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037863835   ⟸   XM_038007907
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037863837   ⟸   XM_038007909
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RXZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037863833   ⟸   XM_038007905
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037863834   ⟸   XM_038007906
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037863836   ⟸   XM_038007908
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RXZ6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017453 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015547.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1110.10 UniProtKB/TrEMBL
  3.40.50.1000 UniProtKB/TrEMBL
  Calcium-transporting ATPase, cytoplasmic transduction domain A UniProtKB/TrEMBL
InterPro ATPase_P-typ_cyto_dom_N UniProtKB/TrEMBL
  ATPase_P-typ_P_site UniProtKB/TrEMBL
  ATPase_P-typ_TM_dom_sf UniProtKB/TrEMBL
  ATPase_P-typ_transduc_dom_A_sf UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  P-type_ATPase_IV UniProtKB/TrEMBL
  P-type_ATPase_N UniProtKB/TrEMBL
  P_typ_ATPase UniProtKB/TrEMBL
  P_typ_ATPase_c UniProtKB/TrEMBL
  P_typ_ATPase_HD_dom UniProtKB/TrEMBL
NCBI Gene ATP11A ENTREZGENE
PANTHER PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE UniProtKB/TrEMBL
  PTHR24092:SF33 UniProtKB/TrEMBL
Pfam Cation_ATPase UniProtKB/TrEMBL
  E1-E2_ATPase UniProtKB/TrEMBL
  PhoLip_ATPase_C UniProtKB/TrEMBL
  PhoLip_ATPase_N UniProtKB/TrEMBL
PRINTS CATATPASE UniProtKB/TrEMBL
PROSITE ATPASE_E1_E2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/TrEMBL
  SSF81653 UniProtKB/TrEMBL
  SSF81660 UniProtKB/TrEMBL
  SSF81665 UniProtKB/TrEMBL
UniProt A0A0D9RXZ6 ENTREZGENE, UniProtKB/TrEMBL