CD180 (CD180 molecule) - Rat Genome Database

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Gene: CD180 (CD180 molecule) Chlorocebus sabaeus
Analyze
Symbol: CD180
Name: CD180 molecule
RGD ID: 18362081
Description: INVOLVED IN B cell proliferation involved in immune response (ortholog); cellular response to lipopolysaccharide (ortholog); lipopolysaccharide-mediated signaling pathway (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD180 antigen
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1463,361,277 - 63,377,492 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl463,359,844 - 63,377,459 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604912,018,496 - 12,039,973 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CD180
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1463,361,277 - 63,377,492 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl463,359,844 - 63,377,459 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604912,018,496 - 12,039,973 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CD180
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38567,179,613 - 67,196,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl567,179,613 - 67,196,799 (-)EnsemblGRCh38hg38GRCh38
GRCh37566,475,441 - 66,492,627 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36566,513,872 - 66,528,368 (-)NCBINCBI36Build 36hg18NCBI36
Build 34566,513,871 - 66,528,368NCBI
Celera563,476,512 - 63,491,026 (-)NCBICelera
Cytogenetic Map5q12.3NCBI
HuRef563,436,781 - 63,451,299 (-)NCBIHuRef
CHM1_1566,478,494 - 66,493,008 (-)NCBICHM1_1
T2T-CHM13v2.0568,001,761 - 68,018,951 (-)NCBIT2T-CHM13v2.0
Cd180
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913102,830,055 - 102,843,139 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13102,830,066 - 102,876,137 (+)EnsemblGRCm39 Ensembl
GRCm3813102,693,547 - 102,706,631 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13102,693,558 - 102,739,629 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713103,483,638 - 103,496,711 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613103,813,970 - 103,827,337 (+)NCBIMGSCv36mm8
Celera13106,283,432 - 106,296,502 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1354.92NCBI
Cd180
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8235,589,889 - 35,602,837 (+)NCBIGRCr8
mRatBN7.2233,855,940 - 33,870,046 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl233,855,991 - 33,899,936 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx240,975,821 - 40,988,664 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0239,034,515 - 39,047,362 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0233,882,318 - 33,895,184 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0232,820,275 - 32,833,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl232,820,322 - 32,833,125 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0251,958,928 - 51,971,865 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4233,609,034 - 33,621,585 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1233,529,523 - 33,541,542 (+)NCBI
Celera229,841,151 - 29,853,945 (+)NCBICelera
Cytogenetic Map2q13NCBI
Cd180
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554461,940,496 - 1,961,287 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554461,940,498 - 1,959,804 (+)NCBIChiLan1.0ChiLan1.0
CD180
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2446,719,183 - 46,734,718 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1544,872,809 - 44,888,345 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0546,799,607 - 46,815,214 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1548,364,874 - 48,381,700 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl548,364,874 - 48,381,694 (+)Ensemblpanpan1.1panPan2
CD180
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1252,644,357 - 52,660,830 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl252,645,766 - 52,660,790 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha249,605,279 - 49,621,785 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0253,143,232 - 53,159,719 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl253,144,431 - 53,159,652 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1250,207,853 - 50,224,342 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0250,990,473 - 51,006,742 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0251,878,479 - 51,894,980 (-)NCBIUU_Cfam_GSD_1.0
Cd180
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213193,168,668 - 193,183,146 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364802,105,084 - 2,119,739 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364802,105,179 - 2,119,137 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD180
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1645,571,173 - 45,588,066 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11645,571,252 - 45,588,032 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21649,212,355 - 49,229,137 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap16q14NCBI
Cd180
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248152,511,552 - 2,529,891 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248152,511,506 - 2,528,396 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 3
Low 29 17 41
Below cutoff 7 19

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007974306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000013988   ⟹   ENSCSAP00000011969
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl463,359,844 - 63,377,459 (-)Ensembl
RefSeq Acc Id: XM_007974306   ⟹   XP_007972497
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1463,361,277 - 63,377,492 (-)NCBI
Vero_WHO_p1.0NW_02366604912,018,496 - 12,039,973 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007972497 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011969.1
Reference Protein Sequences
RefSeq Acc Id: XP_007972497   ⟸   XM_007974306
- UniProtKB: A0A0D9RTN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000011969   ⟸   ENSCSAT00000013988


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015891 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013988.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_11 UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103222550 UniProtKB/TrEMBL
NCBI Gene CD180 ENTREZGENE
PANTHER SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN UniProtKB/TrEMBL
  VASORIN UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_11 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A0D9RTN0 ENTREZGENE, UniProtKB/TrEMBL