STRN4 (striatin 4) - Rat Genome Database

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Gene: STRN4 (striatin 4) Chlorocebus sabaeus
Analyze
Symbol: STRN4
Name: striatin 4
RGD ID: 18360375
Description: ENCODES a protein that exhibits protein domain specific binding (ortholog); protein-containing complex binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of hippo signaling (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2I (ortholog); congenital muscular dystrophy-dystroglycanopathy type A5 (ortholog); genetic disease (ortholog); FOUND IN dendritic spine (ortholog); FAR/SIN/STRIPAK complex (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: striatin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,073,924 - 40,100,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,075,007 - 40,100,885 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,786,014 - 19,812,907 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
STRN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,073,924 - 40,100,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,075,007 - 40,100,885 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,786,014 - 19,812,907 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STRN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,719,511 - 46,746,450 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,719,511 - 46,746,994 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,222,768 - 47,249,707 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,914,608 - 51,941,560 (-)NCBINCBI36Build 36hg18NCBI36
Build 341951,914,609 - 51,941,527NCBI
Celera1944,026,298 - 44,053,250 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,647,696 - 43,674,467 (-)NCBIHuRef
CHM1_11947,224,668 - 47,251,617 (-)NCBICHM1_1
T2T-CHM13v2.01949,545,101 - 49,572,026 (-)NCBIT2T-CHM13v2.0
Strn4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,549,814 - 16,574,856 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,549,814 - 16,574,856 (+)EnsemblGRCm39 Ensembl
GRCm38716,815,889 - 16,840,931 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,815,889 - 16,840,931 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,401,238 - 17,426,280 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,974,411 - 15,999,425 (+)NCBIMGSCv36mm8
Celera714,013,892 - 14,038,921 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Strn4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,614,193 - 86,639,959 (+)NCBIGRCr8
mRatBN7.2177,482,267 - 77,511,862 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,482,094 - 77,511,858 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,866,257 - 82,892,028 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,430,301 - 91,456,072 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,621,348 - 84,647,119 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,739,930 - 78,765,696 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,735,678 - 78,765,692 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,983,369 - 80,012,891 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,140,308 - 77,166,074 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,218,418 - 77,244,183 (+)NCBI
Celera171,971,158 - 71,996,922 (+)NCBICelera
Cytogenetic Map1q21NCBI
Strn4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574752,848 - 771,666 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574752,848 - 771,664 (-)NCBIChiLan1.0ChiLan1.0
STRN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,869,300 - 52,896,212 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,740,168 - 54,767,087 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,711,834 - 43,738,742 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,240,880 - 52,260,241 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,240,880 - 52,260,241 (-)Ensemblpanpan1.1panPan2
STRN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,176,955 - 109,203,875 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,176,983 - 109,202,591 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,656,782 - 108,683,677 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,703,457 - 109,730,350 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,703,016 - 109,730,347 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,380,580 - 109,407,472 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,014,768 - 109,041,665 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,883,463 - 109,910,358 (+)NCBIUU_Cfam_GSD_1.0
Strn4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,935,553 - 18,953,098 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936664553,878 - 570,732 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936664553,682 - 574,240 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STRN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,601,938 - 52,627,902 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,601,934 - 52,627,910 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,922,599 - 47,948,577 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Strn4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,858,123 - 6,883,514 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,858,107 - 6,883,514 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 4 60
Low 16
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000001048   ⟹   ENSCSAP00000015019
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl640,075,007 - 40,100,885 (-)Ensembl
RefSeq Acc Id: XM_007997314   ⟹   XP_007995505
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1640,073,924 - 40,100,822 (-)NCBI
Vero_WHO_p1.0NW_02366607319,786,014 - 19,812,907 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007997315   ⟹   XP_007995506
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1640,073,924 - 40,100,822 (-)NCBI
Vero_WHO_p1.0NW_02366607319,786,014 - 19,812,907 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007995505 (Get FASTA)   NCBI Sequence Viewer  
  XP_007995506 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015019
  ENSCSAP00000015019.1
RefSeq Acc Id: XP_007995506   ⟸   XM_007997315
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007995505   ⟸   XM_007997314
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S2D0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015019   ⟸   ENSCSAT00000001048


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003022 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001048.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.300 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  Striatin_N UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103234923 UniProtKB/TrEMBL
NCBI Gene STRN4 ENTREZGENE
PANTHER STRIATIN UniProtKB/TrEMBL
  STRIATIN-4 UniProtKB/TrEMBL
Pfam Striatin UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9S2D0 ENTREZGENE, UniProtKB/TrEMBL