PYCR2 (pyrroline-5-carboxylate reductase 2)

Gene: PYCR2 (pyrroline-5-carboxylate reductase 2) Chlorocebus sabaeus

Analyze

Symbol:

PYCR2

Name:

pyrroline-5-carboxylate reductase 2

RGD ID:

18355058

Description:

ENCODES a protein that exhibits oxidoreductase activity (inferred); pyrroline-5-carboxylate reductase activity (inferred); INVOLVED IN cellular response to oxidative stress (inferred); L-proline biosynthetic process (inferred); proline biosynthetic process (inferred); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); hypomyelinating leukodystrophy 10 (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

pyrroline-5-carboxylate reductase family member 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	3,846,518 - 3,850,976 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	3,846,501 - 3,851,856 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	3,852,944 - 3,857,403 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

hypomyelinating leukodystrophy 10 (ISO)

microcephaly (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to oxidative stress (IEA)

L-proline biosynthetic process (IEA)

proline biosynthetic process (IEA)

Cellular Component

cytoplasm (IEA)

mitochondrion (IEA)

Molecular Function

oxidoreductase activity (IEA)

protein binding (ISO)

pyrroline-5-carboxylate reductase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

AGAT deficiency pathway (ISO)

arginine and proline metabolic pathway (ISO)

guanidinoacetate methyltransferase deficiency pathway (ISO)

gyrate atrophy pathway (ISO)

hyperprolinemia type I pathway (ISO)

hyperprolinemia type II pathway (ISO)

ornithine translocase deficiency pathway (ISO)

prolidase deficiency pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PYCR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	3,846,518 - 3,850,976 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	3,846,501 - 3,851,856 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	3,852,944 - 3,857,403 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PYCR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	225,919,878 - 225,924,250 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	225,919,877 - 225,924,340 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	226,107,578 - 226,111,950 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	224,174,203 - 224,178,588 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	222,414,315 - 222,418,700	NCBI
Celera	1	199,298,629 - 199,303,014 (-)	NCBI		Celera
Cytogenetic Map	1	q42.12	NCBI
HuRef	1	196,625,292 - 196,629,755 (-)	NCBI		HuRef
CHM1_1	1	227,379,901 - 227,384,364 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	225,107,658 - 225,112,030 (-)	NCBI		T2T-CHM13v2.0

Pycr2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	180,731,839 - 180,735,653 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	180,731,858 - 180,735,653 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	180,904,274 - 180,908,088 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	180,904,293 - 180,908,088 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	182,834,405 - 182,838,219 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	182,740,984 - 182,744,763 (+)	NCBI		MGSCv36	mm8
Celera	1	187,967,388 - 187,971,204 (+)	NCBI		Celera
Cytogenetic Map	1	H4	NCBI
cM Map	1	84.46	NCBI

Pycr2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	95,158,236 - 95,162,030 (+)	NCBI		GRCr8
mRatBN7.2	13	92,626,462 - 92,630,256 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	92,626,471 - 92,634,184 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	95,131,781 - 95,135,575 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	96,531,710 - 96,535,504 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	93,706,406 - 93,710,200 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	99,184,624 - 99,188,418 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	99,184,564 - 99,188,431 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	104,182,905 - 104,186,734 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	96,633,455 - 96,637,249 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	96,822,390 - 96,826,184 (+)	NCBI
Celera	13	92,171,198 - 92,174,992 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

Pycr2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955489	138,600 - 143,112 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955489	138,600 - 143,112 (-)	NCBI	ChiLan1.0	ChiLan1.0

PYCR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	23,612,831 - 23,617,694 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	23,561,603 - 23,566,049 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	201,381,270 - 201,385,703 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	206,381,539 - 206,386,002 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	206,381,539 - 206,386,002 (-)	Ensembl	panpan1.1		panPan2

PYCR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	38,902,705 - 38,905,924 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	38,384,909 - 38,388,130 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	38,736,696 - 38,739,925 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	38,736,694 - 38,739,920 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	38,576,503 - 38,579,717 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	38,584,643 - 38,587,863 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	38,854,425 - 38,857,653 (+)	NCBI		UU_Cfam_GSD_1.0

Pycr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	52,020,591 - 52,025,713 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	2,720,521 - 2,726,762 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	2,721,579 - 2,726,699 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PYCR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	13,838,085 - 13,845,894 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	13,841,755 - 13,845,900 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	15,943,366 - 15,947,506 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Pycr2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	31,830 - 63,985 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624807	37,742 - 63,887 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36	10	49
Low		10	11
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007988276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007988277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007988278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000014411 ⟹ ENSCSAP00000012385

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	25	3,846,501 - 3,851,856 (+)	Ensembl

RefSeq Acc Id:

XM_007988276 ⟹ XP_007986467

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	25	3,846,518 - 3,850,976 (+)	NCBI
Vero_WHO_p1.0	NW_023666055	3,852,944 - 3,857,403 (+)	NCBI

Sequence:

show sequence

GTAGTCCGGCGGGGCGGGGCCACATGGCCTAAGGGGCCATCTGTAGCCCGGGAGATAACCGCTG
GAGGAGTCCAGTGTTGCACCATCCCAGAAACTGCTGTTAGCTCGCCCTCGCTCGGCGCGCCGCC
CGTTGGCCCCTGCGCTGTCCGCCCTTCCCCTAGCGTTATTTCCGGGCCCGCGCTGAGGGGGTTC
CTGCGGCTGCCAGGAGGTGTGAGCCGTGGACCATGAGCGTGGGCATCATCGGAGCCGGCCAGCT
GGCCTATGCTCTGGCGCGGGGCTTCACGGCCGCAGGTATCGTGTCGGCTCACAAGATCATAGCC
AGCTCTCCGGAAATGAACCTGCCCACGGTGTCGGCCCTCAGGAAGATGGGTGTGAACCTGACAC
GCAGCAACAAGGAGACAGTGAAGCACAGGGACGTCCTGTTTCTGGCCGTGAAGCCACATATCAT
CCCCTTCATTTTGGATGAGATTGGGGCCGATGTACAAGCCAGACACATCGTGGTCTCCTGTGCG
GCTGGTGTCACCATCAGCTCTGTGGAGAAGAAGCTGATGGCGTTCCAGCCAGCCCCCAAAGTGA
TTCGCTGCATGACCAACACACCTGTGGTAGTGCGGGAAGGCGCTACAGTGTACGCCATGGGCAC
CCATGCCCTGGTGGAGGATGGGCAGCTCCTGGAGCAGCTCATGAGCAGCGTGGGCTTCTGCACT
GAGGTGGAAGAGGACCTCATCGATGCCGTCACGGGGCTCAGTGGCAGCGGGCCTGCCTATGCAT
TCATGGCTCTGGATGCATTGGCTGATGGTGGGGTGAAGATGGGTTTGCCACGGCGCCTGGCAGT
CCGACTCGGGGCCCAGGCCTTGCTGGGAGCTGCCAAGATGCTGCTGGACTCAGAGCAGCATCCA
TGCCAGCTCAAGGACAATGTCTGCTCCCCTGGGGGAGCCACCATCCACGCCCTGCACTTTCTGG
AGAGTGGGGGCTTCCGCTCTCTGCTCATCAATGCAGTTGAGGCCTCCTGTATCCGAACACGAGA
GCTACAGTCCATGGCCGACCAAGAAAAGATCTCCCCAGCTGCCCTTAAGAAGACGCTCCTAGAC
AGAGTGAAGCTGGAATCCCCCACAGTCTCCACACTGACCCCCTCCAGCCCAGGGAAGCTCCTTA
CAAGAAGCCTGGCCCTGGGTGGCAAGAAGGACTAAGGCAGCATCTACCCCCTCTGTGATTTAGA
GCCCTCAGTTGAGAGCCCCTGCCCCACCCCCTCTGTTGCTCCTCCTCACCTTTGCAAGGAGAAA
GCAGGCTCAGGTAGTTTTCAGGGCTTTGTGATAAAACCTCCTTAAATCTGTTCAGACCAAGCAG
TGTGAGCTTCCTCTCCTGTCCCATGTTGGAAGATGCTCTGAAGGGGTGGTAGATGCTGGAAGCC
AGACACAACCCTGCATACCCCACTCAGTTGGCGGAGGCTGGGGCTGGGACTGGAGTCAGCCCAG
CTGGGAGGAAGGGCTGGGGAGGATCTGCAGCTGAAGCCCAAGGCAGGGTTGGTTTGATGCCAAG
GCAAAGTGGTGAGAGAGAAAATAGGAAAGGGGCTTTTCTCTGAATTGGTAAATGGGAAAGAAGT
GAGCAACTTAAGATTGTCACAATCACAAGTGTACAGGATTAGACTGTGTTTATATTTAACTCTT
GCTTCATAGGTGTACCATTTAAAGAGTGTACCATTTAATGCTAAGTTTAACTGCTTTAATAAAG
TTTATTTTTAAATATC

hide sequence

RefSeq Acc Id:

XM_007988277 ⟹ XP_007986468

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	25	3,846,526 - 3,850,976 (+)	NCBI
Vero_WHO_p1.0	NW_023666055	3,852,950 - 3,857,403 (+)	NCBI

Sequence:

show sequence

GCGGGGCGGGGCCACATGGCCTAAGGGGCCATCTGTAGCCCGGGAGATAACCGCTGGAGGAGTC
CAGTGTTGCACCATCCCAGAAACTGCTGTTAGCTCGCCCTCGCTCGGCGCGCCGCCCGTTGGCC
CCTGCGCTGTCCGCCCTTCCCCTAGCGTTATTTCCGGGCCCGCGCTGAGGGGGTTCCTGCGGCT
GCCAGGAGGTGTGAGCCGTGGACCATGAGCGTGGGCATCATCGGAGCCGGCCAGCTGGCCTATG
CTCTGGCGCGGGGCTTCACGGCCGCAGGTATCGTGTCGGCTCACAAGATCATAGCCAGCTCTCC
GGAAATGAACCTGCCCACGGTGTCGGCCCTCAGGATGGGTGTGAACCTGACACGCAGCAACAAG
GAGACAGTGAAGCACAGGGACGTCCTGTTTCTGGCCGTGAAGCCACATATCATCCCCTTCATTT
TGGATGAGATTGGGGCCGATGTACAAGCCAGACACATCGTGGTCTCCTGTGCGGCTGGTGTCAC
CATCAGCTCTGTGGAGAAGAAGCTGATGGCGTTCCAGCCAGCCCCCAAAGTGATTCGCTGCATG
ACCAACACACCTGTGGTAGTGCGGGAAGGCGCTACAGTGTACGCCATGGGCACCCATGCCCTGG
TGGAGGATGGGCAGCTCCTGGAGCAGCTCATGAGCAGCGTGGGCTTCTGCACTGAGGTGGAAGA
GGACCTCATCGATGCCGTCACGGGGCTCAGTGGCAGCGGGCCTGCCTATGCATTCATGGCTCTG
GATGCATTGGCTGATGGTGGGGTGAAGATGGGTTTGCCACGGCGCCTGGCAGTCCGACTCGGGG
CCCAGGCCTTGCTGGGAGCTGCCAAGATGCTGCTGGACTCAGAGCAGCATCCATGCCAGCTCAA
GGACAATGTCTGCTCCCCTGGGGGAGCCACCATCCACGCCCTGCACTTTCTGGAGAGTGGGGGC
TTCCGCTCTCTGCTCATCAATGCAGTTGAGGCCTCCTGTATCCGAACACGAGAGCTACAGTCCA
TGGCCGACCAAGAAAAGATCTCCCCAGCTGCCCTTAAGAAGACGCTCCTAGACAGAGTGAAGCT
GGAATCCCCCACAGTCTCCACACTGACCCCCTCCAGCCCAGGGAAGCTCCTTACAAGAAGCCTG
GCCCTGGGTGGCAAGAAGGACTAAGGCAGCATCTACCCCCTCTGTGATTTAGAGCCCTCAGTTG
AGAGCCCCTGCCCCACCCCCTCTGTTGCTCCTCCTCACCTTTGCAAGGAGAAAGCAGGCTCAGG
TAGTTTTCAGGGCTTTGTGATAAAACCTCCTTAAATCTGTTCAGACCAAGCAGTGTGAGCTTCC
TCTCCTGTCCCATGTTGGAAGATGCTCTGAAGGGGTGGTAGATGCTGGAAGCCAGACACAACCC
TGCATACCCCACTCAGTTGGCGGAGGCTGGGGCTGGGACTGGAGTCAGCCCAGCTGGGAGGAAG
GGCTGGGGAGGATCTGCAGCTGAAGCCCAAGGCAGGGTTGGTTTGATGCCAAGGCAAAGTGGTG
AGAGAGAAAATAGGAAAGGGGCTTTTCTCTGAATTGGTAAATGGGAAAGAAGTGAGCAACTTAA
GATTGTCACAATCACAAGTGTACAGGATTAGACTGTGTTTATATTTAACTCTTGCTTCATAGGT
GTACCATTTAAAGAGTGTACCATTTAATGCTAAGTTTAACTGCTTTAATAAAGTTTATTTTTAA
ATATC

hide sequence

RefSeq Acc Id:

XM_007988278 ⟹ XP_007986469

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	25	3,846,525 - 3,850,976 (+)	NCBI
Vero_WHO_p1.0	NW_023666055	3,852,950 - 3,857,403 (+)	NCBI

Sequence:

show sequence

GGCGGGGCGGGGCCACATGGCCTAAGGGGCCATCTGTAGCCCGGGAGATAACCGCTGGAGGAGT
CCAGTGTTGCACCATCCCAGAAACTGCTGTTAGCTCGCCCTCGCTCGGCGCGCCGCCCGTTGGC
CCCTGCGCTGTCCGCCCTTCCCCTAGCGTTATTTCCGGGCCCGCGCTGAGGGGGTTCCTGCGGC
TGCCAGGAGGTGTGAGCCGTGGACCATGAGCGTGGGCATCATCGGAGCCGGCCAGCTGGCCTAT
GCTCTGGCGCGGGGCTTCACGGCCGCAGGTATCGTGTCGGCTCACAAGATCATAGCCAGCTCTC
CGGAAATGAACCTGCCCACGGTGTCGGCCCTCAGGAAGCTGATGGCGTTCCAGCCAGCCCCCAA
AGTGATTCGCTGCATGACCAACACACCTGTGGTAGTGCGGGAAGGCGCTACAGTGTACGCCATG
GGCACCCATGCCCTGGTGGAGGATGGGCAGCTCCTGGAGCAGCTCATGAGCAGCGTGGGCTTCT
GCACTGAGGTGGAAGAGGACCTCATCGATGCCGTCACGGGGCTCAGTGGCAGCGGGCCTGCCTA
TGCATTCATGGCTCTGGATGCATTGGCTGATGGTGGGGTGAAGATGGGTTTGCCACGGCGCCTG
GCAGTCCGACTCGGGGCCCAGGCCTTGCTGGGAGCTGCCAAGATGCTGCTGGACTCAGAGCAGC
ATCCATGCCAGCTCAAGGACAATGTCTGCTCCCCTGGGGGAGCCACCATCCACGCCCTGCACTT
TCTGGAGAGTGGGGGCTTCCGCTCTCTGCTCATCAATGCAGTTGAGGCCTCCTGTATCCGAACA
CGAGAGCTACAGTCCATGGCCGACCAAGAAAAGATCTCCCCAGCTGCCCTTAAGAAGACGCTCC
TAGACAGAGTGAAGCTGGAATCCCCCACAGTCTCCACACTGACCCCCTCCAGCCCAGGGAAGCT
CCTTACAAGAAGCCTGGCCCTGGGTGGCAAGAAGGACTAAGGCAGCATCTACCCCCTCTGTGAT
TTAGAGCCCTCAGTTGAGAGCCCCTGCCCCACCCCCTCTGTTGCTCCTCCTCACCTTTGCAAGG
AGAAAGCAGGCTCAGGTAGTTTTCAGGGCTTTGTGATAAAACCTCCTTAAATCTGTTCAGACCA
AGCAGTGTGAGCTTCCTCTCCTGTCCCATGTTGGAAGATGCTCTGAAGGGGTGGTAGATGCTGG
AAGCCAGACACAACCCTGCATACCCCACTCAGTTGGCGGAGGCTGGGGCTGGGACTGGAGTCAG
CCCAGCTGGGAGGAAGGGCTGGGGAGGATCTGCAGCTGAAGCCCAAGGCAGGGTTGGTTTGATG
CCAAGGCAAAGTGGTGAGAGAGAAAATAGGAAAGGGGCTTTTCTCTGAATTGGTAAATGGGAAA
GAAGTGAGCAACTTAAGATTGTCACAATCACAAGTGTACAGGATTAGACTGTGTTTATATTTAA
CTCTTGCTTCATAGGTGTACCATTTAAAGAGTGTACCATTTAATGCTAAGTTTAACTGCTTTAA
TAAAGTTTATTTTTAAATATC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007986467	(Get FASTA)	NCBI Sequence Viewer
	XP_007986468	(Get FASTA)	NCBI Sequence Viewer
	XP_007986469	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000012385.1

RefSeq Acc Id:	XP_007986467 ⟸ XM_007988276
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RUU6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007986469 ⟸ XM_007988278
- Peptide Label:	isoform X3
- UniProtKB:	A0A0D9RUU6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007986468 ⟸ XM_007988277
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RUU6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000012385 ⟸ ENSCSAT00000014411

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000016314	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000014411.1	UniProtKB/TrEMBL
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
	ProC C-terminal domain-like	UniProtKB/TrEMBL
InterPro	6-PGluconate_DH-like_C_sf	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	P5C_Rdtase_cat_N	UniProtKB/TrEMBL
	P5CR_dimer	UniProtKB/TrEMBL
	Pyrroline-COOH_reductase	UniProtKB/TrEMBL
KEGG Report	csab:103230000	UniProtKB/TrEMBL
NCBI Gene	PYCR2	ENTREZGENE
PANTHER	PTHR11645	UniProtKB/TrEMBL
	PYRROLINE-5-CARBOXYLATE REDUCTASE 2	UniProtKB/TrEMBL
Pfam	F420_oxidored	UniProtKB/TrEMBL
	P5CR_dimer	UniProtKB/TrEMBL
PIRSF	Pyrrol-5-carb_rd	UniProtKB/TrEMBL
PROSITE	P5CR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48179	UniProtKB/TrEMBL
	SSF51735	UniProtKB/TrEMBL
UniProt	A0A0D9RUU6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB