SH3KBP1 (SH3 domain containing kinase binding protein 1) - Rat Genome Database

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Gene: SH3KBP1 (SH3 domain containing kinase binding protein 1) Chlorocebus sabaeus
Analyze
Symbol: SH3KBP1
Name: SH3 domain containing kinase binding protein 1
RGD ID: 18346138
Description: ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN actin filament organization (inferred); cell migration (inferred); cytoskeleton organization (inferred); ASSOCIATED WITH autistic disorder (ortholog); Coffin-Lowry syndrome (ortholog); Colonic Neoplasms (ortholog); FOUND IN cell-cell junction (inferred); cytoplasm (inferred); endocytic vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SH3 domain-containing kinase-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X17,999,262 - 18,357,003 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX17,999,211 - 18,357,157 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605619,857,065 - 20,214,417 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
SH3KBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X17,999,262 - 18,357,003 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX17,999,211 - 18,357,157 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605619,857,065 - 20,214,417 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SH3KBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X19,533,977 - 19,887,600 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX19,533,977 - 19,887,600 (-)EnsemblGRCh38hg38GRCh38
GRCh37X19,552,095 - 19,905,718 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X19,463,441 - 19,815,640 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X19,313,176 - 19,665,376NCBI
CeleraX23,675,636 - 24,008,177 (-)NCBICelera
Cytogenetic MapXp22.12NCBI
HuRefX17,300,128 - 17,651,187 (-)NCBIHuRef
CHM1_1X19,582,478 - 19,936,208 (-)NCBICHM1_1
T2T-CHM13v2.0X19,116,856 - 19,470,507 (-)NCBIT2T-CHM13v2.0
Sh3kbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X158,409,888 - 158,758,916 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX158,410,268 - 158,761,065 (+)EnsemblGRCm39 Ensembl
GRCm38X159,626,892 - 159,975,920 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX159,627,272 - 159,978,069 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X156,065,340 - 156,413,849 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X155,052,706 - 155,318,272 (+)NCBIMGSCv36mm8
CeleraX142,872,597 - 143,219,835 (+)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX73.65NCBI
Sh3kbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X38,686,530 - 39,031,658 (-)NCBIGRCr8
mRatBN7.2X34,877,862 - 35,223,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX34,877,866 - 35,222,747 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX36,015,061 - 36,359,892 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X39,478,687 - 39,823,541 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X34,644,756 - 34,989,581 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X37,790,004 - 38,196,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX37,790,586 - 38,196,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X38,094,434 - 38,505,289 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X56,075,533 - 56,422,980 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X56,129,005 - 56,476,449 (-)NCBI
CeleraX35,544,608 - 35,884,206 (-)NCBICelera
Cytogenetic MapXq14NCBI
Sh3kbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555094,960 - 345,012 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555096,157 - 344,930 (-)NCBIChiLan1.0ChiLan1.0
SH3KBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X21,332,665 - 21,689,981 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X21,336,054 - 21,693,305 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X12,154,789 - 12,511,949 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X19,517,952 - 19,822,925 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX19,517,952 - 19,822,931 (-)Ensemblpanpan1.1panPan2
SH3KBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X15,482,593 - 15,818,113 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX15,484,680 - 15,817,967 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X15,442,674 - 15,782,235 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX15,441,780 - 15,779,762 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X15,491,286 - 15,830,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X15,493,198 - 15,832,564 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X15,560,580 - 15,900,196 (-)NCBIUU_Cfam_GSD_1.0
Sh3kbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X8,541,179 - 8,830,808 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366244,327,031 - 4,615,699 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366244,327,100 - 4,616,724 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3KBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX15,885,069 - 16,224,183 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X15,887,131 - 16,229,212 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X17,136,481 - 17,492,932 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sh3kbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248294,329,824 - 4,714,298 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248294,329,959 - 4,714,329 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 35 17 46
Low 1 3 14
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000012683   ⟹   ENSCSAP00000010714
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblX17,999,211 - 18,357,157 (-)Ensembl
RefSeq Acc Id: XM_007991224   ⟹   XP_007989415
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X17,999,262 - 18,356,980 (-)NCBI
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,417 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007991225   ⟹   XP_007989416
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X17,999,262 - 18,270,297 (-)NCBI
Vero_WHO_p1.0NW_02366605619,857,065 - 20,127,433 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007991227   ⟹   XP_007989418
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X17,999,262 - 18,357,003 (-)NCBI
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,417 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007991228   ⟹   XP_007989419
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X17,999,262 - 18,270,281 (-)NCBI
Vero_WHO_p1.0NW_02366605619,857,065 - 20,127,458 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007991229   ⟹   XP_007989420
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X17,999,262 - 18,356,977 (-)NCBI
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,417 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007991230   ⟹   XP_007989421
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X17,999,262 - 18,141,490 (-)NCBI
Vero_WHO_p1.0NW_02366605619,857,065 - 19,998,438 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037986381   ⟹   XP_037842309
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,417 (-)NCBI
RefSeq Acc Id: XM_037986382   ⟹   XP_037842310
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,406 (-)NCBI
RefSeq Acc Id: XM_037986383   ⟹   XP_037842311
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,417 (-)NCBI
RefSeq Acc Id: XM_037986384   ⟹   XP_037842312
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,417 (-)NCBI
RefSeq Acc Id: XM_037986385   ⟹   XP_037842313
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605619,857,066 - 20,214,406 (-)NCBI
RefSeq Acc Id: XM_037986386   ⟹   XP_037842314
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605619,857,065 - 19,998,450 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007989418   ⟸   XM_007991227
- Peptide Label: isoform X6
RefSeq Acc Id: XP_007989415   ⟸   XM_007991224
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007989420   ⟸   XM_007991229
- Peptide Label: isoform X10
RefSeq Acc Id: XP_007989416   ⟸   XM_007991225
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007989419   ⟸   XM_007991228
- Peptide Label: isoform X8
RefSeq Acc Id: XP_007989421   ⟸   XM_007991230
- Peptide Label: isoform X11
RefSeq Acc Id: ENSCSAP00000010714   ⟸   ENSCSAT00000012683
RefSeq Acc Id: XP_037842314   ⟸   XM_037986386
- Peptide Label: isoform X12
RefSeq Acc Id: XP_037842312   ⟸   XM_037986384
- Peptide Label: isoform X7
RefSeq Acc Id: XP_037842309   ⟸   XM_037986381
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RQ25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842311   ⟸   XM_037986383
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037842313   ⟸   XM_037986385
- Peptide Label: isoform X9
RefSeq Acc Id: XP_037842310   ⟸   XM_037986382
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014593 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012683.1 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/TrEMBL
InterPro CIN85_SH3_1 UniProtKB/TrEMBL
  CIN85_SH3_2 UniProtKB/TrEMBL
  CIN85_SH3_3 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene SH3KBP1 ENTREZGENE
PANTHER PTHR14167:SF6 UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam SH3_9 UniProtKB/TrEMBL
PRINTS P67PHOX UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
UniProt A0A0D9RQ25 ENTREZGENE, UniProtKB/TrEMBL