PRSS36 (serine protease 36) - Rat Genome Database

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Gene: PRSS36 (serine protease 36) Chlorocebus sabaeus
Analyze
Symbol: PRSS36
Name: serine protease 36
RGD ID: 18339347
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polyserase-2; protease, serine 36
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,829,359 - 27,840,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl527,827,511 - 27,839,907 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660681,626,683 - 1,637,574 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PRSS36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,829,359 - 27,840,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl527,827,511 - 27,839,907 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660681,626,683 - 1,637,574 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PRSS36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381631,138,926 - 31,150,066 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1631,138,926 - 31,150,083 (-)EnsemblGRCh38hg38GRCh38
GRCh371631,150,247 - 31,161,387 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361631,057,750 - 31,068,888 (-)NCBINCBI36Build 36hg18NCBI36
Celera1629,136,608 - 29,147,773 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1628,711,400 - 28,723,215 (-)NCBIHuRef
CHM1_11632,467,970 - 32,479,132 (-)NCBICHM1_1
T2T-CHM13v2.01631,526,407 - 31,537,545 (-)NCBIT2T-CHM13v2.0
Prss36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,531,810 - 127,545,897 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,531,810 - 127,545,897 (-)EnsemblGRCm39 Ensembl
GRCm387127,932,638 - 127,946,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,932,638 - 127,946,725 (-)EnsemblGRCm38mm10GRCm38
MGSCv377135,076,152 - 135,090,239 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,723,784 - 127,737,873 (-)NCBIMGSCv36mm8
Celera7127,767,827 - 127,781,907 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.84NCBI
Prss36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,973,556 - 192,002,231 (-)NCBIGRCr8
mRatBN7.21182,543,085 - 182,561,141 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,543,085 - 182,559,280 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,893,626 - 190,909,613 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01198,079,717 - 198,095,704 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01190,750,112 - 190,766,179 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,379,374 - 199,396,339 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,379,374 - 199,395,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,402,154 - 206,419,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,217,603 - 187,233,400 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1180,193,893 - 180,209,989 (-)NCBICelera
Cytogenetic Map1q37NCBI
Prss36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,979,292 - 7,990,673 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,979,080 - 7,985,028 (-)NCBIChiLan1.0ChiLan1.0
PRSS36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21834,344,932 - 34,356,186 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11639,146,331 - 39,157,584 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01623,818,719 - 23,829,983 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11631,507,244 - 31,518,727 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1631,507,455 - 31,518,727 (-)Ensemblpanpan1.1panPan2
PRSS36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,096,996 - 17,107,676 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,096,996 - 17,107,420 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha618,672,381 - 18,683,065 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,228,763 - 17,238,603 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,227,413 - 17,238,612 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,028,146 - 17,038,823 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0616,947,167 - 16,957,836 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,260,231 - 17,270,035 (+)NCBIUU_Cfam_GSD_1.0
Prss36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344125,393,862 - 125,406,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650113,494,831 - 13,503,977 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650113,494,628 - 13,504,042 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRSS36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,345,892 - 17,354,665 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,345,015 - 17,354,688 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2317,517,635 - 17,526,482 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 35 20 52
Below cutoff 1 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000003753   ⟹   ENSCSAP00000002025
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl527,827,511 - 27,839,907 (-)Ensembl
RefSeq Acc Id: XM_007990615   ⟹   XP_007988806
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1527,829,359 - 27,840,677 (-)NCBI
Vero_WHO_p1.0NW_0236660681,626,683 - 1,637,574 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007990623   ⟹   XP_007988814
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1527,829,359 - 27,840,674 (-)NCBI
Vero_WHO_p1.0NW_0236660681,626,684 - 1,637,574 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007988806 (Get FASTA)   NCBI Sequence Viewer  
  XP_007988814 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000002025
  ENSCSAP00000002025.1
Reference Protein Sequences
RefSeq Acc Id: XP_007988806   ⟸   XM_007990615
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R086 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007988814   ⟸   XM_007990623
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000002025   ⟸   ENSCSAT00000003753


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005720 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003753.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Pept_S1A_polyserase-2 UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report csab:103231313 UniProtKB/TrEMBL
NCBI Gene PRSS36 ENTREZGENE
PANTHER POLYSERASE-2 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEASE SERINE UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PIRSF Polyserase-2 UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A0D9R086 ENTREZGENE, UniProtKB/TrEMBL