HSPA2-AS1 (HSPA2 and ZBTB1 antisense RNA 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: HSPA2-AS1 (HSPA2 and ZBTB1 antisense RNA 1) Homo sapiens
Analyze
Symbol: HSPA2-AS1
Name: HSPA2 and ZBTB1 antisense RNA 1
RGD ID: 16562025
HGNC Page HGNC:55433
Description: ASSOCIATED WITH genetic disease
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: AL049869.2; AL049869.3; LOC102723809; novel transcript, antisense to HSPA2 & ZBTB1; uncharacterized LOC102723809
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38.p14 Ensembl - Human Genome Assembly GRCh38 Ensembl
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,514,151 - 64,540,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1464,513,952 - 64,540,368 (-)EnsemblGRCh38hg38GRCh38
GRCh371464,980,869 - 65,007,086 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map14q23.3NCBI
CHM1_11464,920,542 - 64,946,781 (-)NCBICHM1_1
T2T-CHM13v2.01458,721,912 - 58,748,166 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Variants

.
Variants in HSPA2-AS1
15 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001123329.2(ZBTB1):c.1272G>C (p.Glu424Asp) single nucleotide variant Inborn genetic diseases [RCV003245933] Chr14:64522776 [GRCh38]
Chr14:64989494 [GRCh37]
Chr14:14q23.3
uncertain significance
GRCh38/hg38 14q23.2-23.3(chr14:62252700-65753416)x1 copy number loss See cases [RCV000138250] Chr14:62252700..65753416 [GRCh38]
Chr14:62719418..66220134 [GRCh37]
Chr14:61789171..65289887 [NCBI36]
Chr14:14q23.2-23.3
pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33
pathogenic
GRCh38/hg38 14q23.1-23.3(chr14:59917051-66750803)x1 copy number loss See cases [RCV000050892] Chr14:59917051..66750803 [GRCh38]
Chr14:60383769..67217521 [GRCh37]
Chr14:59453522..66287274 [NCBI36]
Chr14:14q23.1-23.3
pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33
pathogenic
GRCh38/hg38 14q22.3-23.3(chr14:57041036-67208231)x1 copy number loss See cases [RCV000051521] Chr14:57041036..67208231 [GRCh38]
Chr14:57507754..67674948 [GRCh37]
Chr14:56577507..66744701 [NCBI36]
Chr14:14q22.3-23.3
pathogenic
NM_001123329.2(ZBTB1):c.899G>A (p.Gly300Glu) single nucleotide variant Inborn genetic diseases [RCV003299297] Chr14:64522403 [GRCh38]
Chr14:64989121 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1509G>A (p.Met503Ile) single nucleotide variant Inborn genetic diseases [RCV002687102] Chr14:64523013 [GRCh38]
Chr14:64989731 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.940G>A (p.Glu314Lys) single nucleotide variant Inborn genetic diseases [RCV002759630] Chr14:64522444 [GRCh38]
Chr14:64989162 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.626C>T (p.Ser209Leu) single nucleotide variant Inborn genetic diseases [RCV002911678] Chr14:64522130 [GRCh38]
Chr14:64988848 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1640A>G (p.Asn547Ser) single nucleotide variant Inborn genetic diseases [RCV002737986] Chr14:64523144 [GRCh38]
Chr14:64989862 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.2010A>G (p.Ile670Met) single nucleotide variant Inborn genetic diseases [RCV002984202] Chr14:64523514 [GRCh38]
Chr14:64990232 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1506T>G (p.Asp502Glu) single nucleotide variant Inborn genetic diseases [RCV002987618] Chr14:64523010 [GRCh38]
Chr14:64989728 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.739A>T (p.Thr247Ser) single nucleotide variant Inborn genetic diseases [RCV002787702] Chr14:64522243 [GRCh38]
Chr14:64988961 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1250A>G (p.Asp417Gly) single nucleotide variant Inborn genetic diseases [RCV002981913] Chr14:64522754 [GRCh38]
Chr14:64989472 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1033A>G (p.Ile345Val) single nucleotide variant Inborn genetic diseases [RCV002702393] Chr14:64522537 [GRCh38]
Chr14:64989255 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1505A>G (p.Asp502Gly) single nucleotide variant Inborn genetic diseases [RCV002897496] Chr14:64523009 [GRCh38]
Chr14:64989727 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1984A>G (p.Thr662Ala) single nucleotide variant Inborn genetic diseases [RCV002836433] Chr14:64523488 [GRCh38]
Chr14:64990206 [GRCh37]
Chr14:14q23.3
uncertain significance
NM_001123329.2(ZBTB1):c.1001T>C (p.Ile334Thr) single nucleotide variant Inborn genetic diseases [RCV003195489] Chr14:64522505 [GRCh38]
Chr14:64989223 [GRCh37]
Chr14:14q23.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:50
Interacting mature miRNAs:50
Transcripts:ENST00000554918
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 1 63 1 5 2 307 1 3
Low 1993 1661 1241 314 942 165 3524 1213 1376 240 968 1387 156 1055 2115 2
Below cutoff 387 960 384 231 540 220 743 893 1814 127 112 155 15 142 627 1

Sequence


RefSeq Acc Id: ENST00000554918
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,514,154 - 64,540,368 (-)Ensembl
RefSeq Acc Id: ENST00000648003
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,513,952 - 64,539,621 (-)Ensembl
RefSeq Acc Id: NR_110550
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,514,151 - 64,540,368 (-)NCBI
T2T-CHM13v2.01458,721,912 - 58,748,166 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC HSPA2-AS1 COSMIC
Ensembl Genes ENSG00000259116 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000554918 ENTREZGENE
GTEx ENSG00000259116 GTEx
HGNC ID HGNC:55433 ENTREZGENE
Human Proteome Map HSPA2-AS1 Human Proteome Map
NCBI Gene LOC102723809 ENTREZGENE
RNAcentral URS000075A2E9 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-18 HSPA2-AS1  HSPA2 and ZBTB1 antisense RNA 1  AL049869.2  novel transcript, antisense to HSPA2 & ZBTB1  Symbol and/or name change 19259463 PROVISIONAL
2020-12-03 AL049869.2  novel transcript, antisense to HSPA2 & ZBTB1  AL049869.3  novel transcript, antisense to HSPA2 & ZBTB1  Symbol and/or name change 19259462 PROVISIONAL
2020-06-25 AL049869.3  novel transcript, antisense to HSPA2 & ZBTB1  LOC102723809  uncharacterized LOC102723809  Symbol and/or name change 19259462 PROVISIONAL
2020-06-18 LOC102723809  uncharacterized LOC102723809  AL049869.3  novel transcript, antisense to HSPA2 & ZBTB1  Symbol and/or name change 5135510 APPROVED