AC073130.1 (uncharacterized LOC102724434) - Rat Genome Database

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Gene: AC073130.1 (uncharacterized LOC102724434) Homo sapiens
Analyze
Symbol: AC073130.1
Name: uncharacterized LOC102724434
RGD ID: 16556987
Description:
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: LOC102724434
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38.p14 Ensembl - Human Genome Assembly GRCh38 Ensembl
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387116,275,606 - 116,286,727 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7116,275,606 - 116,286,734 (-)EnsemblGRCh38hg38GRCh38
GRCh377115,915,660 - 115,926,781 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map7q31.2NCBI
CHM1_17115,848,860 - 115,859,981 (-)NCBICHM1_1
T2T-CHM13v2.07117,590,594 - 117,601,715 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:12690205   PMID:14702039  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7q31.2(chr7:115042242-116687714)x3 copy number gain See cases [RCV000053575] Chr7:115042242..116687714 [GRCh38]
Chr7:114682296..116327768 [GRCh37]
Chr7:114469532..116115004 [NCBI36]
Chr7:7q31.2		 pathogenic
GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3 copy number gain See cases [RCV000136717] Chr7:97419852..158923762 [GRCh38]
Chr7:97049164..158716453 [GRCh37]
Chr7:96887100..158409214 [NCBI36]
Chr7:7q21.3-36.3		 pathogenic
GRCh38/hg38 7q22.1-31.31(chr7:102196924-121278641)x1 copy number loss See cases [RCV000137522] Chr7:102196924..121278641 [GRCh38]
Chr7:101912320..120918695 [GRCh37]
Chr7:101626924..120705931 [NCBI36]
Chr7:7q22.1-31.31		 pathogenic
GRCh38/hg38 7q31.1-31.2(chr7:114389395-117253741)x1 copy number loss See cases [RCV000143413] Chr7:114389395..117253741 [GRCh38]
Chr7:114029450..116893795 [GRCh37]
Chr7:113816686..116681031 [NCBI36]
Chr7:7q31.1-31.2		 pathogenic
GRCh38/hg38 7q31.1-31.33(chr7:113799835-124899218)x1 copy number loss See cases [RCV000054160] Chr7:113799835..124899218 [GRCh38]
Chr7:113439890..124539272 [GRCh37]
Chr7:113227126..124326508 [NCBI36]
Chr7:7q31.1-31.33		 pathogenic
GRCh38/hg38 7q31.1-31.31(chr7:114898882-117790123)x1 copy number loss See cases [RCV000142459] Chr7:114898882..117790123 [GRCh38]
Chr7:114538937..117430177 [GRCh37]
Chr7:114326173..117217413 [NCBI36]
Chr7:7q31.1-31.31		 pathogenic
GRCh38/hg38 7q31.1-31.33(chr7:114142477-125840381)x1 copy number loss See cases [RCV000135311] Chr7:114142477..125840381 [GRCh38]
Chr7:113782532..125480435 [GRCh37]
Chr7:113569768..125267671 [NCBI36]
Chr7:7q31.1-31.33		 pathogenic
GRCh38/hg38 7q31.1-31.2(chr7:113604778-117643891) copy number loss Autism spectrum disorder [RCV003883405] Chr7:113604778..117643891 [GRCh38]
Chr7:7q31.1-31.2		 pathogenic
GRCh38/hg38 7q31.2-36.3(chr7:115459015-159325817)x3 copy number gain See cases [RCV000141413] Chr7:115459015..159325817 [GRCh38]
Chr7:115099069..159118507 [GRCh37]
Chr7:114886305..158811268 [NCBI36]
Chr7:7q31.2-36.3		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:284
Count of miRNA genes:260
Interacting mature miRNAs:268
Transcripts:ENST00000415502, ENST00000420594, ENST00000454897, ENST00000457033
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 2 3 1 70 2
Low 16 129 192 5 12 7 223 31 96 29 325 250 5 24 176
Below cutoff 1332 1463 669 165 324 110 2355 934 731 138 568 1130 61 974 1460 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000415502
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7116,283,841 - 116,286,195 (-)Ensembl
RefSeq Acc Id: ENST00000420594
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7116,277,132 - 116,286,734 (-)Ensembl
RefSeq Acc Id: ENST00000454897
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7116,277,003 - 116,286,651 (-)Ensembl
RefSeq Acc Id: ENST00000457033
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7116,275,606 - 116,286,664 (-)Ensembl
RefSeq Acc Id: NR_130921
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387116,275,606 - 116,286,664 (-)NCBI
T2T-CHM13v2.07117,590,594 - 117,601,652 (-)NCBI
Sequence:
RefSeq Acc Id: NR_130922
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387116,275,606 - 116,286,727 (-)NCBI
T2T-CHM13v2.07117,590,594 - 117,601,715 (-)NCBI
Sequence:
RefSeq Acc Id: NR_130923
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387116,275,606 - 116,286,664 (-)NCBI
T2T-CHM13v2.07117,590,594 - 117,601,652 (-)NCBI
Sequence:
Protein Sequences
GenBank Protein EAL24363 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences


Additional Information

Database Acc Id Source(s)
COSMIC AC073130.1 COSMIC
Ensembl Genes ENSG00000237870 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000457033 ENTREZGENE
GTEx ENSG00000237870 GTEx
Human Proteome Map AC073130.1 Human Proteome Map
NCBI Gene LOC102724434 ENTREZGENE
RNAcentral URS00008120F9 RNACentral
  URS000081219A RNACentral
  URS0000D58520 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-08-20 AC073130.1  uncharacterized LOC102724434  AC073130.1  novel transcript  Symbol and/or name change 19259462 PROVISIONAL
2020-06-25 AC073130.1  novel transcript  LOC102724434  uncharacterized LOC102724434  Symbol and/or name change 19259462 PROVISIONAL
2020-06-18 LOC102724434  uncharacterized LOC102724434  AC073130.1  novel transcript  Symbol and/or name change 5135510 APPROVED
2020-02-07 AC073130.1  novel transcript  AC073130.1  uncharacterized LOC102724434  Symbol and/or name change 19259462 PROVISIONAL