Mir497 (microRNA 497) - Rat Genome Database

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Gene: Mir497 (microRNA 497) Mus musculus
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Symbol: Mir497
Name: microRNA 497
RGD ID: 1625952
MGI Page MGI
Description: Acts upstream of or within response to bacterium; response to oxygen levels; and sensory perception of sound. Is expressed in Meckel's cartilage; axial skeleton; brain; limb long bone; and pelvic girdle skeleton. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Orthologous to human MIR497 (microRNA 497).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: Mir; mir-497a; Mirn; Mirn497; mmu-mir-4; mmu-mir-497; mmu-mir-497a
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,125,543 - 70,125,626 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,125,543 - 70,125,626 (+)EnsemblGRCm39 Ensembl
GRCm381170,234,717 - 70,234,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,234,717 - 70,234,800 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,048,219 - 70,048,302 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1177,779,191 - 77,779,274 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. miR‑497 suppresses malignant phenotype in non‑small cell lung cancer via targeting KDR. Xia Y, etal., Oncol Rep. 2019 Jul;42(1):443-452. doi: 10.3892/or.2019.7163. Epub 2019 May 16.
Additional References at PubMed
PMID:16381832   PMID:16582102   PMID:17604727   PMID:18723672   PMID:20215419   PMID:20413612   PMID:20558326   PMID:20668074   PMID:21037258   PMID:21267068   PMID:21718763   PMID:22052914  
PMID:23646144   PMID:24205035   PMID:25119651   PMID:26303911   PMID:26502925   PMID:26567220   PMID:26683705   PMID:27303812   PMID:27992564   PMID:28095641   PMID:28098218   PMID:28685750  
PMID:29620142   PMID:31148190   PMID:31646591   PMID:32591941   PMID:32705746   PMID:33954185   PMID:34068160   PMID:34459097   PMID:34775365   PMID:34944037   PMID:35413277   PMID:36790665  


Genomics

Comparative Map Data
Mir497
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,125,543 - 70,125,626 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,125,543 - 70,125,626 (+)EnsemblGRCm39 Ensembl
GRCm381170,234,717 - 70,234,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,234,717 - 70,234,800 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,048,219 - 70,048,302 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1177,779,191 - 77,779,274 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
MIR497
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,017,911 - 7,018,022 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,017,911 - 7,018,022 (-)EnsemblGRCh38hg38GRCh38
GRCh37176,921,230 - 6,921,341 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36176,861,953 - 6,862,064 (-)NCBINCBI36Build 36hg18NCBI36
Celera176,946,735 - 6,946,846 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef176,814,923 - 6,815,034 (-)NCBIHuRef
CHM1_1176,930,660 - 6,930,771 (-)NCBICHM1_1
T2T-CHM13v2.0176,918,511 - 6,918,622 (-)NCBIT2T-CHM13v2.0
Mir497
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,450,171 - 55,450,239 (+)NCBIGRCr8
mRatBN7.21054,951,514 - 54,951,582 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,951,505 - 54,951,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,631,024 - 59,631,092 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,119,623 - 59,119,691 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,618,747 - 54,618,815 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,844,977 - 56,845,045 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,844,977 - 56,845,045 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,589,141 - 56,589,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1054,102,981 - 54,103,049 (+)NCBICelera
Cytogenetic Map10q24NCBI
MIR497
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,045,759 - 32,045,825 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,045,759 - 32,045,825 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,184,479 - 32,184,545 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,150,741 - 32,150,807 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,150,741 - 32,150,807 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,116,798 - 32,116,864 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,076,043 - 32,076,109 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,252,533 - 32,252,599 (-)NCBIUU_Cfam_GSD_1.0
MIR497
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,422,330 - 52,422,411 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,422,329 - 52,422,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,717,025 - 54,717,104 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:26218
Count of gene targets:10707
Count of transcripts:18364
Interacting mature miRNAs:mmu-miR-497-3p, mmu-miR-497-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000200557
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,125,543 - 70,125,626 (+)Ensembl
GRCm38.p6 Ensembl1170,234,717 - 70,234,800 (+)Ensembl
RefSeq Acc Id: NR_030444
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,125,543 - 70,125,626 (+)NCBI
GRCm381170,234,717 - 70,234,800 (+)ENTREZGENE
MGSCv371170,048,219 - 70,048,302 (+)RGD
Celera1177,779,191 - 77,779,274 (+)RGD
cM Map11 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3629886 AgrOrtholog
Ensembl Genes ENSMUSG00000105220 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000200557 ENTREZGENE
MGD MGI:3629886 ENTREZGENE
miRBase MI0004636 ENTREZGENE
NCBI Gene 751537 ENTREZGENE
PhenoGen Mir497 PhenoGen
RNAcentral URS00002AE1D6 RNACentral
  URS00005A753E RNACentral
  URS000075DE0E RNACentral