Mir497 (microRNA 497) - Rat Genome Database

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Gene: Mir497 (microRNA 497) Mus musculus
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Symbol: Mir497
Name: microRNA 497
RGD ID: 1625952
MGI Page MGI
Description: Acts upstream of or within response to bacterium; response to oxygen levels; and sensory perception of sound. Is expressed in Meckel's cartilage; axial skeleton; brain; limb long bone; and pelvic girdle skeleton. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Orthologous to human MIR497 (microRNA 497).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mir; mir-497a; Mirn; Mirn497; mmu-mir-4; mmu-mir-497; mmu-mir-497a
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,125,543 - 70,125,626 (+)NCBIGRCm39mm39
GRCm39 Ensembl1170,125,543 - 70,125,626 (+)Ensembl
GRCm381170,234,717 - 70,234,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,234,717 - 70,234,800 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,048,219 - 70,048,302 (+)NCBIGRCm37mm9NCBIm37
Celera1177,779,191 - 77,779,274 (+)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

Additional References at PubMed
PMID:16381832   PMID:16582102   PMID:17604727   PMID:18723672   PMID:20215419   PMID:20413612   PMID:20558326   PMID:20668074   PMID:21037258   PMID:21267068   PMID:21718763   PMID:22052914  
PMID:23646144   PMID:24205035   PMID:25119651   PMID:26303911   PMID:26502925   PMID:26567220   PMID:26683705   PMID:27303812   PMID:27992564   PMID:28095641   PMID:28098218   PMID:28685750  
PMID:29620142   PMID:29852387   PMID:31148190   PMID:31646591   PMID:33954185   PMID:34068160  


Genomics

Comparative Map Data
Mir497
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,125,543 - 70,125,626 (+)NCBIGRCm39mm39
GRCm39 Ensembl1170,125,543 - 70,125,626 (+)Ensembl
GRCm381170,234,717 - 70,234,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,234,717 - 70,234,800 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,048,219 - 70,048,302 (+)NCBIGRCm37mm9NCBIm37
Celera1177,779,191 - 77,779,274 (+)NCBICelera
Cytogenetic Map11B3NCBI
MIR497
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,017,911 - 7,018,022 (-)EnsemblGRCh38hg38GRCh38
GRCh38177,017,911 - 7,018,022 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37176,921,230 - 6,921,341 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36176,861,953 - 6,862,064 (-)NCBINCBI36hg18NCBI36
Celera176,946,735 - 6,946,846 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef176,814,923 - 6,815,034 (-)NCBIHuRef
CHM1_1176,930,660 - 6,930,771 (-)NCBICHM1_1
Mir497
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,951,514 - 54,951,582 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1054,951,505 - 54,951,584 (+)Ensembl
Rnor_6.01056,844,977 - 56,845,045 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,844,977 - 56,845,045 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,589,141 - 56,589,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1054,102,981 - 54,103,049 (+)NCBICelera
Cytogenetic Map10q24NCBI
MIR497
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,045,759 - 32,045,825 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,045,759 - 32,045,825 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,184,479 - 32,184,545 (-)NCBI
ROS_Cfam_1.0532,150,741 - 32,150,807 (-)NCBI
UMICH_Zoey_3.1532,116,798 - 32,116,864 (-)NCBI
UNSW_CanFamBas_1.0532,076,043 - 32,076,109 (-)NCBI
UU_Cfam_GSD_1.0532,252,533 - 32,252,599 (-)NCBI
MIR497
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,422,330 - 52,422,411 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,422,329 - 52,422,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,717,025 - 54,717,104 (+)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116910000072600000Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116910000072600000Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116910000072600000Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116910000072600000Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116910000072600000Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116910000072600000Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116910000072600000Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116910000072600000Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116910000072600000Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Bcl2l2mmu-miR-497-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI20053374
Elnmmu-miR-497-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//Western bloFunctional MTI21305018
Igf1rmmu-miR-497-5pOncomiRDBexternal_infoNANA23453369
Bcl2l2mmu-miR-497-5pOncomiRDBexternal_infoNANA22969914
Igf1rmmu-miR-497-5pOncomiRDBexternal_infoNANA22710713
Ccnd1mmu-miR-497-5pOncomiRDBexternal_infoNANA21350001
Bcl2mmu-miR-497-5pOncomiRDBexternal_infoNANA21258880
Bcl2mmu-miR-497-3pMirecordsexternal_infoNANA20053374
Bcl2mmu-miR-497-3pMirecordsexternal_info{changed}NA20053374

Predicted Targets
Summary Value
Count of predictions:26218
Count of gene targets:10707
Count of transcripts:18364
Interacting mature miRNAs:mmu-miR-497-3p, mmu-miR-497-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000200557
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,125,543 - 70,125,626 (+)Ensembl
GRCm38.p6 Ensembl1170,234,717 - 70,234,800 (+)Ensembl
RefSeq Acc Id: NR_030444
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,125,543 - 70,125,626 (+)NCBI
GRCm381170,234,717 - 70,234,800 (+)ENTREZGENE
MGSCv371170,048,219 - 70,048,302 (+)RGD
Celera1177,779,191 - 77,779,274 (+)RGD
cM Map11 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3629886 AgrOrtholog
Ensembl Genes ENSMUSG00000105220 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000200557 ENTREZGENE
MGD MGI:3629886 ENTREZGENE
miRBase MI0004636 ENTREZGENE
NCBI Gene 751537 ENTREZGENE
PhenoGen Mir497 PhenoGen
RNAcentral URS00002AE1D6 RNACentral
  URS00005A753E RNACentral
  URS000075DE0E RNACentral