Mir146b (microRNA 146b) - Rat Genome Database
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Gene: Mir146b (microRNA 146b) Mus musculus
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Symbol: Mir146b
Name: microRNA 146b
RGD ID: 1625939
MGI Page MGI
Description: Orthologous to human MIR146B (microRNA 146b).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-146b; Mirn1; Mirn146b
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391946,331,201 - 46,331,309 (+)NCBIGRCm39mm39
GRCm39 Ensembl1946,331,201 - 46,331,309 (+)Ensembl
GRCm381946,342,762 - 46,342,870 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1946,342,762 - 46,342,870 (+)EnsemblGRCm38mm10GRCm38
MGSCv371946,417,252 - 46,417,360 (+)NCBIGRCm37mm9NCBIm37
Celera1947,106,096 - 47,106,204 (+)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:16381832   PMID:16582102   PMID:17604727   PMID:18723672   PMID:19188425   PMID:20215419   PMID:20413612   PMID:20805985   PMID:21037258   PMID:21247879   PMID:21267068   PMID:21822254  
PMID:22564414   PMID:22895573   PMID:23071818   PMID:23646144   PMID:24009212   PMID:24477912   PMID:24735967   PMID:24956113   PMID:26722482   PMID:27825654   PMID:28713933   PMID:28714020  
PMID:29843156   PMID:29951922   PMID:30013024   PMID:30073586   PMID:30500983   PMID:30530754   PMID:30867482   PMID:31156641   PMID:31422941   PMID:32051823  


Genomics

Comparative Map Data
Mir146b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391946,331,201 - 46,331,309 (+)NCBIGRCm39mm39
GRCm39 Ensembl1946,331,201 - 46,331,309 (+)Ensembl
GRCm381946,342,762 - 46,342,870 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1946,342,762 - 46,342,870 (+)EnsemblGRCm38mm10GRCm38
MGSCv371946,417,252 - 46,417,360 (+)NCBIGRCm37mm9NCBIm37
Celera1947,106,096 - 47,106,204 (+)NCBICelera
Cytogenetic Map19C3NCBI
MIR146B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10102,436,512 - 102,436,584 (+)EnsemblGRCh38hg38GRCh38
GRCh3810102,436,512 - 102,436,584 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710104,196,269 - 104,196,341 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610104,186,258 - 104,186,330 (+)NCBINCBI36hg18NCBI36
Celera1097,937,172 - 97,937,244 (+)NCBI
Cytogenetic Map10q24.32NCBI
HuRef1097,829,357 - 97,829,429 (+)NCBIHuRef
CHM1_110104,479,721 - 104,479,793 (+)NCBICHM1_1
Mir146b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21245,203,438 - 245,203,525 (+)NCBI
Rnor_6.0 Ensembl1266,089,488 - 266,089,575 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01266,089,488 - 266,089,575 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01273,520,429 - 273,520,516 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,558,047 - 251,558,134 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1240,986,212 - 240,986,299 (+)NCBICelera
Cytogenetic Map1q54NCBI
MIR146B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2814,940,550 - 14,940,610 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12814,940,550 - 14,940,610 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
MIR146B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.114113,446,854 - 113,446,952 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214123,301,752 - 123,301,850 (+)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10413881Moe2_mmodifier of epilepsy 2 (mouse)191494561648945738Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191593520749935319Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191593520749935319Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191831776252317981Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191831776252317981Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192025691554257062Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192025691554257062Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192139025755390480Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192233596253923073Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192500000059000000Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192543847859438566Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192739715561397266Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2815190961431566Mouse
4141562Pas3b_mpulmonary adenoma susceptibility 3b (mouse)Not determined2977296261431566Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193015278561431566Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193015279261431566Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193015279261431566Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193090944161431566Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193300371961431566Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193396351461431566Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3460834861431566Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193603954446773082Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193676416661431566Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193789455061431566Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193838761861431566Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193919563261431566Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193960763461431566Mouse
1300585Pgia12_mproteoglycan induced arthritis 12 (mouse)Not determined194259842761431566Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Smad4mmu-miR-146b-5pOncomiRDBexternal_infoNANA21874046
Brca1mmu-miR-146b-5pOncomiRDBexternal_infoNANA21472990
Egfrmmu-miR-146b-5pOncomiRDBexternal_infoNANA20874002
Mmp16mmu-miR-146b-5pOncomiRDBexternal_infoNANA19265686
Rock1mmu-miR-146b-5pOncomiRDBexternal_infoNANA18174313

Predicted Targets
Summary Value
Count of predictions:22362
Count of gene targets:10093
Count of transcripts:16841
Interacting mature miRNAs:mmu-miR-146b-3p, mmu-miR-146b-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000093619
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1946,342,762 - 46,342,870 (+)Ensembl
RefSeq Acc Id: NR_030468
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391946,331,201 - 46,331,309 (+)NCBI
GRCm381946,342,762 - 46,342,870 (+)ENTREZGENE
MGSCv371946,417,252 - 46,417,360 (+)RGD
Celera1947,106,096 - 47,106,204 (+)RGD
cM Map19 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3629945 AgrOrtholog
Ensembl Genes ENSMUSG00000070127 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000093619 ENTREZGENE
MGD MGI:3629945 ENTREZGENE
miRBase MI0004665 ENTREZGENE
NCBI Gene 751550 ENTREZGENE
PhenoGen Mir146b PhenoGen
RNAcentral URS00004F546B RNACentral
  URS000061B694 RNACentral
  URS000075A148 RNACentral