Mir684-2 (microRNA 684-2) - Rat Genome Database
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Pathways
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Gene: Mir684-2 (microRNA 684-2) Mus musculus
Analyze
Symbol: Mir684-2
Name: microRNA 684-2
RGD ID: 1625886
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mirn68; Mirn684-2
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39411,134,097 - 11,134,182 (+)NCBIGRCm39mm39
GRCm39 Ensembl411,134,097 - 11,134,182 (+)Ensembl
GRCm38411,134,097 - 11,134,182 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl411,134,097 - 11,134,182 (+)EnsemblGRCm38mm10GRCm38
MGSCv37411,061,244 - 11,061,329 (+)NCBIGRCm37mm9NCBIm37
Celera410,944,788 - 10,944,873 (+)NCBICelera
Cytogenetic Map4A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:16582102   PMID:21267068   PMID:21822254  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301274Lmr9_mleishmaniasis resistance 9 (mouse)Not determined4120657234Mouse
11049579Lmr9b_mleishmaniasis resistance 9b (mouse)4120657234Mouse
11049580Lmr9a_mleishmaniasis resistance 9 (mouse)4120657234Mouse
10412079Sm1_msusceptibility to Schistosoma mansoni infection 1 (mouse)Not determined4122955614Mouse
1301510Bbaa13_mB.burgdorferi-associated arthritis 13 (mouse)Not determined4126395649Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:12097
Count of gene targets:6136
Count of transcripts:9376
Interacting mature miRNAs:mmu-miR-684
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_030455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL840625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000197598
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl411,134,097 - 11,134,182 (+)Ensembl
RefSeq Acc Id: NR_030455
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39411,134,097 - 11,134,182 (+)NCBI
GRCm38411,134,097 - 11,134,182 (+)ENTREZGENE
MGSCv37411,061,244 - 11,061,329 (+)RGD
Celera410,944,788 - 10,944,873 (+)RGD
cM Map4 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000105333 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000197598 ENTREZGENE
MGD MGI:3629642 ENTREZGENE
miRBase MI0004648 ENTREZGENE
NCBI Gene 735261 ENTREZGENE
PhenoGen Mir684-2 PhenoGen
RNAcentral URS0000504B2B RNACentral
  URS000075B9D0 RNACentral