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Gene: XAGE1A (X antigen family member 1A) Homo sapiens
Symbol: XAGE1A
Name: X antigen family member 1A
Description: This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 12.1; cancer/testis antigen family 12, member 1a; cancer/testis antigen family 12, member 1b; cancer/testis associated protein; CT12.1; CT12.1A; CT12.1b; CTP9; G antigen family D member 2; G antigen, family D, 2; GAGED2; X antigen family member 1; X antigen family member 1B; XAGE-1; XAGE1; XAGE1B; XAGE1C; XAGE1D; XAGE1E; XAGE1E.
No known orthologs. homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: There are two XAGE1 loci on the X chromosome. This location, previously annotated as XAGE1B, is now annotated as XAGE1A. [01 Dec 2017]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX52,495,808 - 52,500,812 (+)Ensembl
GRCh38X52,495,668 - 52,500,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X52,238,810 - 52,243,954 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X52,557,778 - 52,562,914 (-)NCBINCBI36hg18NCBI36
Cytogenetic MapXp11.22NCBI
CHM1_1X52,506,938 - 52,507,050 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on XAGE1A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1625833
Created: 2007-07-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.