Pgls (6-phosphogluconolactonase) - Rat Genome Database

Name: Pgls
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Pgls (6-phosphogluconolactonase) Mus musculus

Analyze

Symbol:

Pgls

Name:

6-phosphogluconolactonase

RGD ID:

1625472

MGI Page

MGI

Description:

Predicted to have 6-phosphogluconolactonase activity and monosaccharide binding activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Predicted to localize to cytoplasm. Is expressed in cerebellum; hemolymphoid system; and thymus primordium. Orthologous to human PGLS (6-phosphogluconolactonase); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomerase deficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

1110030K05Rik; 6PGL; AI447866; Plgs

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PGLS (6-phosphogluconolactonase)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Pgls (6-phosphogluconolactonase)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Pgls (6-phosphogluconolactonase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PGLS (6-phosphogluconolactonase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PGLS (6-phosphogluconolactonase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pgls (6-phosphogluconolactonase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PGLS (6-phosphogluconolactonase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	PGLS (6-phosphogluconolactonase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pgls (6-phosphogluconolactonase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Pgls (6-phosphogluconolactonase)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	PGLS (6-phosphogluconolactonase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	pgls (6-phosphogluconolactonase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam\|ZFIN)
Drosophila melanogaster (fruit fly):	CG17333	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	SOL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	SOL2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	SOL3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	SOL4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Caenorhabditis elegans (roundworm):	Y57G11C.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	72,044,828 - 72,048,911 (+)	NCBI	GRCm39		mm39
GRCm38	8	71,592,184 - 71,596,267 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	71,592,176 - 71,601,092 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	74,116,083 - 74,120,166 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	74,521,173 - 74,525,256 (+)	NCBI			mm8
Celera	8	74,106,490 - 74,110,576 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

osteoporosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-butoxyethanol (EXP)

4,4'-sulfonyldiphenol (ISO)

acetamide (ISO)

aflatoxin B1 (EXP,ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (ISO)

bisphenol F (ISO)

butan-1-ol (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chlorpyrifos (ISO)

choline (EXP)

cisplatin (ISO)

clofibrate (EXP)

crocidolite asbestos (EXP,ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dioxygen (EXP)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

folic acid (EXP)

hyaluronic acid (ISO)

hydrogen peroxide (ISO)

hydroquinone (ISO)

L-methionine (EXP)

methylmercury chloride (ISO)

N-nitrosomorpholine (ISO)

pirinixic acid (EXP)

piroxicam (ISO)

sodium fluoride (EXP)

T-2 toxin (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (EXP)

thimerosal (ISO)

thioacetamide (ISO)

trichloroethene (EXP)

tungsten (EXP)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA)

pentose-phosphate shunt (ISO)

pentose-phosphate shunt, oxidative branch (IBA,ISO)

Cellular Component

cytoplasm (IBA)

Molecular Function

6-phosphogluconolactonase activity (IBA,ISO)

hydrolase activity (IEA)

monosaccharide binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

pentose phosphate pathway (IEA,ISO)

pentose phosphate pathway - oxidative phase (ISO)

ribose 5-phosphate isomerase deficiency pathway (ISO)

transaldolase deficiency pathway (ISO)

References

References - curated


1.	Pipeline to import KEGG annotations from KEGG into RGD
2.	Pipeline to import SMPDB annotations from SMPDB into RGD
3.	RGD automated import pipeline for gene-chemical interactions
4.	Schofield PJ and Sols A, Biochem Biophys Res Commun. 1976 Aug 23;71(4):1313-8.

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:14681479	PMID:15018818	PMID:15489334	PMID:15782199	PMID:16141072
PMID:16141073	PMID:21267068	PMID:21677750	PMID:21873635	PMID:28245920	PMID:30457570	PMID:30713523	PMID:31779658

Genomics

Comparative Map Data

Pgls
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	72,044,828 - 72,048,911 (+)	NCBI	GRCm39		mm39
GRCm38	8	71,592,184 - 71,596,267 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	71,592,176 - 71,601,092 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	74,116,083 - 74,120,166 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	74,521,173 - 74,525,256 (+)	NCBI			mm8
Celera	8	74,106,490 - 74,110,576 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI

PGLS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	19	17,511,636 - 17,521,288 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	19	17,511,649 - 17,521,291 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	19	17,622,278 - 17,632,097 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	17,483,432 - 17,493,097 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	17,483,431 - 17,493,095	NCBI
Celera	19	17,524,049 - 17,533,713 (+)	NCBI
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	17,187,513 - 17,197,177 (+)	NCBI		HuRef
CHM1_1	19	17,621,814 - 17,631,479 (+)	NCBI		CHM1_1

Pgls
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	16	20,020,444 - 20,025,930 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	20,020,444 - 20,025,930 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	19,880,872 - 19,886,358 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	18,791,241 - 18,796,727 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	16	18,792,185 - 18,796,720 (+)	NCBI
Celera	16	18,504,223 - 18,509,709 (+)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Pgls
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	793,239 - 801,107 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	797,439 - 801,070 (-)	NCBI	ChiLan1.0	ChiLan1.0

PGLS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	17,971,544 - 17,980,431 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	17,971,544 - 17,980,431 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	16,998,851 - 17,008,558 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

PGLS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	20	45,294,008 - 45,301,038 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	20	45,293,970 - 45,301,074 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Pgls
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936596	3,414,003 - 3,422,467 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PGLS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	60,164,259 - 60,197,648 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	60,186,690 - 60,198,037 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	59,778,632 - 59,787,018 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PGLS
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,997,865 - 16,006,137 (+)	NCBI
ChlSab1.1 Ensembl	6	15,997,806 - 16,006,805 (+)	Ensembl

Pgls
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624908	522,698 - 526,526 (-)	NCBI

Position Markers

AI447866

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	71,600,765 - 71,601,019	UniSTS	GRCm38
MGSCv37	8	74,124,664 - 74,124,918	UniSTS	GRCm37
Celera	8	74,115,073 - 74,115,327	UniSTS
Cytogenetic Map	8	C1	UniSTS
Cytogenetic Map	8	B3.3	UniSTS
Whitehead/MRC_RH	8	765.18	UniSTS

Pgls

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	8	C1	UniSTS
cM Map	8		UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
14747005	Mancz7_m	mandible centroid size 7 (mouse)					8	50053306	84053306	Mouse
27226754	Femd6_m	femur midshaft diameter 6, 10 week (mouse)					8	37400000	109600000	Mouse
10766466	Char12_m	P. chabaudi malaria resistance QTL 12 (mouse)					8	68269827	82600347	Mouse
1301872	Cd4ts3_m	CD4 T cell subset 3 (mouse)			Not determined		8	71396181	105396393	Mouse
1301952	Im3_m	immunoregulatory 3 (mouse)			Not determined		8	54706614	88706763	Mouse
14700686	Civq3_m	cerebral infarct volume QTL 3 (mouse)					8	51882191	85882191	Mouse
1357787	Vtbt5_m	vertebral trabecular bone trait 5 (mouse)			Not determined		8	65357768	99357920	Mouse
1301544	Iba3_m	induction of brown adipocytes 3 (mouse)			Not determined		8	44294880	78295025	Mouse
4142283	Imraq2_m	immune response to AAV2 QTL 2 (mouse)			Not determined		8	70305375	104305495	Mouse
1301441	Skull11_m	skull morphology 11 (mouse)			Not determined		8	47737134	81737254	Mouse
4141395	Char2a_m	P. chabaudi malaria resistance QTL 2a (mouse)			Not determined			71136783	90202598	Mouse
10766453	Char11_m	P. chabaudi malaria resistance QTL 11 (mouse)					8	47637030	81637146	Mouse
10412287	Carg3_m	Candida albicans resistance gene 3 (mouse)			Not determined		8	55545028	89545028	Mouse
14746987	Manh64_m	mandible shape 64 (mouse)					8	50053306	84053306	Mouse
1558875	Eae31_m	experimental allergic encephalomyelitis susceptibility 31 (mouse)			Not determined		8	34642776	114837007	Mouse
12904744	Carcdq1_m	cardiac collagen deposition QTL 1 (mouse)					8	39709256	94689598	Mouse
4141797	Skmw16_m	skeletal muscle weight 16 (mouse)			Not determined		8	63939547	97939696	Mouse
1301767	Fcsa2_m	femoral cross-sectional area 2 (mouse)			Not determined		8	70305375	104305495	Mouse
4142023	W3q5_m	weight 3 weeks QTL 5 (mouse)			Not determined			71287817	123895615	Mouse
10043992	Hbnr11_m	Heligmosomoides bakeri nematode resistance 11 (mouse)			Not determined		8	65600207	99600347	Mouse
1357708	Orq1_m	ovulation rate QTL 1 (mouse)			Not determined		8	71287817	123895615	Mouse
10043975	Obq31_m	obesity QTL 31 (mouse)			Not determined		8	58409776	92409776	Mouse
1558780	Idd22_m	insulin dependent diabetes susceptibility 22 (mouse)			Not determined		8	71102903	105103009	Mouse
4141285	Tgq18_m	triglyceride QTL 18 (mouse)			Not determined			63460107	97460107	Mouse
11353828	Gf7_m	gonadal fat pad weight 7 (mouse)					8	58201479	92201479	Mouse
1301506	Aevm1_m	autoimmune extremity vasculitis in MRL mice 1 (mouse)			Not determined		8	54287817	88287993	Mouse
1301013	Capsq4_m	capsaicin sensitivity related QTL 4 (mouse)			Not determined		8	36163000	92728652	Mouse
4140967	Bmd39_m	bone mineral density 39 (mouse)			Not determined		8	32016544	117238700	Mouse
1357715	Alaa3_m	alopecia areata 3 (mouse)			Not determined		8	48792939	82793021	Mouse
1301688	Orch6_m	autoimmune orchitis resistance 6 (mouse)			Not determined		8	60786850	94786976	Mouse
1301717	Adip4_m	adiposity 4 (mouse)			Not determined		8	47637030	81637146	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	989
Count of miRNA genes:	526
Interacting mature miRNAs:	621
Transcripts:	ENSMUST00000034264, ENSMUST00000123240, ENSMUST00000127626, ENSMUST00000138742, ENSMUST00000143441
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001294269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_025396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC162033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK028344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK036059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK044914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK080749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK172066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK178168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK188109	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK189281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC006594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE654173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000034264 ⟹ ENSMUSP00000034264

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,592,176 - 71,596,269 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000123240

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,592,211 - 71,595,665 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000127626 ⟹ ENSMUSP00000122042

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,592,184 - 71,601,092 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000138742 ⟹ ENSMUSP00000120113

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,592,237 - 71,595,111 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000143441 ⟹ ENSMUSP00000116524

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,592,291 - 71,596,269 (+)	Ensembl

RefSeq Acc Id:

NM_001294269 ⟹ NP_001281198

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	72,044,828 - 72,048,911 (+)	NCBI
GRCm38	8	71,592,184 - 71,596,267 (+)	NCBI
Celera	8	74,106,490 - 74,110,576 (+)	NCBI

Sequence:

show sequence

CTCTGCCGGGAGCGCCGCCGCCTCCCCACCGCCATGGCAGCACCCGCGCCCAGTCTCATCTCGG
TCTTCTCCAGCCCGCAAGAGCTGGGCGCGTCGCTGGCGCAGCTGGTGGCGCAGCGGGCCGCGAG
CTGCCTGGAAGGGGACCGTGGCCGCTTCGCGCTTGGTCTGTCAGGCGGCAGCCTGGTCTCCATG
CTAGCCCGAGACCTGCCCGCCGCCGCCGCTCCCGCTGGACCAGCCAGCTTTGCGCGCTGGACGC
TCGGCTTCTGCGACGAGCGCCTCGTGCCCTTCGACCACGCCGAGAGCACGTACGGCCTCTACCG
GGTGAGCGCTGCGGGGGCGCGCACCGTACGGGCTACGGGGGCCGCCGTGGGCCACGCCGAGCTG
GCTCAGCCTACCGTGGAAACTCAAGATACAAGGGCCGCCGTGGGCCACGCGGAGTCGGCTCAGT
CCGCCGAGGAAGCGCGGGCCACGCCGAACTGGCTCAGCCTGCCTAGGAAACGCAAGGATCTGCT
TCAACGCCTACCCGCGGGCTCCGGGCCCCACGGGGTCTTGCTGGATGCGCAGTGATGTCCATCC
AAGTGCAGCCTGACGGGCCTCCGTCCCCCACACACCTGCTCTCAAAGCTGCCCATCCCAGACAG
CCAGGTCCTTACCATCAATCCTGCCCTACCTGTGGAGGATGCTGCAGAGGACTATGCCAGGAAA
CTGAGACAGGCCTTGCAAGGAGACGCTGTCCCTGTGTTTGACCTGCTGATCCTGGGAGTGGGCC
CTGACGGCCATACCTGTTCGCTCTTCCCTGACCATCCCCTCCTACAGGAGCGGGAGAAGATCGT
GGCTCCCATCAGTGACTCCCCAAAGCCACCACCGCAGAGGGTGACCCTAACGCTTCCTGTGCTG
AACGCAGCCCAAAGTATCATCTTTGTGGCCACGGGGGAAGGCAAGGCAGCTGTGCTGAAGCGCA
TCCTGGAGGACAAGGAGGGCACGTTGCCCGCCGCCTTGGTGCAGCCGCGCACGGGCGCCCTCTG
CTGGTTCCTGGACGAGGCAGCTGCCCGGCTGCTGTCTGTGCCCTTCGAGAAGCATTCCACATTG
TAGGGGGTGCGCCATGCACGCCGTGGGCACTTCGGGTGTTGTGGGAGCGGACTAGCTGCGGATT
AAACAGCTTTGCTGG

hide sequence

RefSeq Acc Id:

NM_025396 ⟹ NP_079672

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	72,044,828 - 72,048,911 (+)	NCBI
GRCm38	8	71,592,184 - 71,596,267 (+)	NCBI
MGSCv37	8	74,116,083 - 74,120,166 (+)	RGD
Celera	8	74,106,490 - 74,110,576 (+)	RGD
cM Map	8		ENTREZGENE

Sequence:

show sequence

CTCTGCCGGGAGCGCCGCCGCCTCCCCACCGCCATGGCAGCACCCGCGCCCAGTCTCATCTCGG
TCTTCTCCAGCCCGCAAGAGCTGGGCGCGTCGCTGGCGCAGCTGGTGGCGCAGCGGGCCGCGAG
CTGCCTGGAAGGGGACCGTGGCCGCTTCGCGCTTGGTCTGTCAGGCGGCAGCCTGGTCTCCATG
CTAGCCCGAGACCTGCCCGCCGCCGCCGCTCCCGCTGGACCAGCCAGCTTTGCGCGCTGGACGC
TCGGCTTCTGCGACGAGCGCCTCGTGCCCTTCGACCACGCCGAGAGCACGTACGGCCTCTACCG
GACACACCTGCTCTCAAAGCTGCCCATCCCAGACAGCCAGGTCCTTACCATCAATCCTGCCCTA
CCTGTGGAGGATGCTGCAGAGGACTATGCCAGGAAACTGAGACAGGCCTTGCAAGGAGACGCTG
TCCCTGTGTTTGACCTGCTGATCCTGGGAGTGGGCCCTGACGGCCATACCTGTTCGCTCTTCCC
TGACCATCCCCTCCTACAGGAGCGGGAGAAGATCGTGGCTCCCATCAGTGACTCCCCAAAGCCA
CCACCGCAGAGGGTGACCCTAACGCTTCCTGTGCTGAACGCAGCCCAAAGTATCATCTTTGTGG
CCACGGGGGAAGGCAAGGCAGCTGTGCTGAAGCGCATCCTGGAGGACAAGGAGGGCACGTTGCC
CGCCGCCTTGGTGCAGCCGCGCACGGGCGCCCTCTGCTGGTTCCTGGACGAGGCAGCTGCCCGG
CTGCTGTCTGTGCCCTTCGAGAAGCATTCCACATTGTAGGGGGTGCGCCATGCACGCCGTGGGC
ACTTCGGGTGTTGTGGGAGCGGACTAGCTGCGGATTAAACAGCTTTGCTGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001281198	(Get FASTA)	NCBI Sequence Viewer
	NP_079672	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH06594	(Get FASTA)	NCBI Sequence Viewer
	BAB22594	(Get FASTA)	NCBI Sequence Viewer
	BAB23106	(Get FASTA)	NCBI Sequence Viewer
	BAC29292	(Get FASTA)	NCBI Sequence Viewer
	BAE42808	(Get FASTA)	NCBI Sequence Viewer
	EDL28944	(Get FASTA)	NCBI Sequence Viewer
	EDL28945	(Get FASTA)	NCBI Sequence Viewer
	Q9CQ60	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_079672 ⟸ NM_025396
- Peptide Label:	isoform 1
- UniProtKB:	Q9CQ60 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAAPAPSLISVFSSPQELGASLAQLVAQRAASCLEGDRGRFALGLSGGSLVSMLARDLPAAAAP AGPASFARWTLGFCDERLVPFDHAESTYGLYRTHLLSKLPIPDSQVLTINPALPVEDAAEDYAR KLRQALQGDAVPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPV LNAAQSIIFVATGEGKAAVLKRILEDKEGTLPAALVQPRTGALCWFLDEAAARLLSVPFEKHST L hide sequence

RefSeq Acc Id:	NP_001281198 ⟸ NM_001294269
- Peptide Label:	isoform 2
- UniProtKB:	Q9CQ60 (UniProtKB/Swiss-Prot), D3Z4X1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSIQVQPDGPPSPTHLLSKLPIPDSQVLTINPALPVEDAAEDYARKLRQALQGDAVPVFDLLIL GVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAAQSIIFVATGEGKAAV LKRILEDKEGTLPAALVQPRTGALCWFLDEAAARLLSVPFEKHSTL hide sequence

RefSeq Acc Id:

ENSMUSP00000120113 ⟸ ENSMUST00000138742

RefSeq Acc Id:

ENSMUSP00000116524 ⟸ ENSMUST00000143441

RefSeq Acc Id:

ENSMUSP00000034264 ⟸ ENSMUST00000034264

RefSeq Acc Id:

ENSMUSP00000122042 ⟸ ENSMUST00000127626

Protein Domains

Glucosamine_iso

Promoters

RGD ID:

8667415

Promoter ID:

EPDNEW_M11739

Type:

initiation region

Name:

Pgls_1

Description:

Mus musculus 6-phosphogluconolactonase , transcript variant 1,mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	71,592,207 - 71,592,267	EPDNEW

RGD ID:

6843601

Promoter ID:

MM_KWN:54801

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000085618, OTTMUST00000085619, OTTMUST00000085620, OTTMUST00000085621, OTTMUST00000085622

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	74,115,116 - 74,117,942 (+)	MPROMDB

RGD ID:

6848332

Promoter ID:

MM_ACW:47904

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day2, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4

Transcripts:

PGLSANDBCNP1.MSEP07-UNSPLICED

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	74,119,749 - 74,120,249 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1913421	AgrOrtholog
Ensembl Genes	ENSMUSG00000031807	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000034264	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000116524	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUSP00000120113	UniProtKB/TrEMBL
	ENSMUSP00000122042	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000034264	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000127626	UniProtKB/TrEMBL
	ENSMUST00000138742	UniProtKB/TrEMBL
	ENSMUST00000143441	ENTREZGENE, UniProtKB/TrEMBL
InterPro	6-phosphogluconolactonase_DevB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glc/Gal-6P_isomerase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NagB/RpiA_transferase-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PGLS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:66171	UniProtKB/Swiss-Prot
MGD	MGI:1913421	ENTREZGENE
NCBI Gene	66171	ENTREZGENE
PANTHER	PTHR11054	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Glucosamine_iso	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pgls	PhenoGen
Superfamily-SCOP	SSF100950	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs	pgl	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Mm.282284	ENTREZGENE
	Mm.402679	ENTREZGENE
UniProt	6PGL_MOUSE	UniProtKB/Swiss-Prot
	D3Z4X1	ENTREZGENE, UniProtKB/TrEMBL
	F6X8L5_MOUSE	UniProtKB/TrEMBL
	Q8CBG6_MOUSE	UniProtKB/TrEMBL
	Q9CQ60	ENTREZGENE
UniProt Secondary	Q3TA62	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)