Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19095052 | 4,4'-sulfonyldiphenol | increases methylation | ISO | ZSCAN18 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of ZSCAN18 gene | CTD | PMID:31601247 | 5-fluorouracil | affects response to substance | ISO | ZSCAN18 (Homo sapiens) | 6480464 | ZSCAN18 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | acrolein | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ZSCAN18 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ZSCAN18 mRNA | CTD | PMID:32699268 | alpha-pinene | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ZSCAN18 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ZSCAN18 mRNA | CTD | PMID:32699268 | aristolochic acid A | increases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ZSCAN18 mRNA | CTD | PMID:33212167 | arsenite(3-) | decreases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | arsenite results in decreased expression of ZSCAN18 mRNA | CTD | PMID:23974009 | arsenite(3-) | increases methylation | ISO | ZSCAN18 (Homo sapiens) | 6480464 | arsenite results in increased methylation of ZSCAN18 promoter | CTD | PMID:23974009 | benzo[a]pyrene | increases methylation | ISO | ZSCAN18 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ZSCAN18 exon and Benzo(a)pyrene results in increased methylation of ZSCAN18 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | ZSCAN18 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ZSCAN18 3' UTR | CTD | PMID:27901495 | bisphenol A | affects expression | ISO | Zscan18 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ZSCAN18 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ZSCAN18 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Zscan18 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ZSCAN18 mRNA | CTD | PMID:30816183 | bromobenzene | increases expression | ISO | Zscan18 (Rattus norvegicus) | 6480464 | bromobenzene results in increased expression of ZSCAN18 mRNA | CTD | PMID:32479839 | CGP 52608 | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ZSCAN18 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of ZSCAN18 mRNA | CTD | PMID:37019170 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ZSCAN18 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZSCAN18 mRNA | CTD | PMID:27188386 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of ZSCAN18 mRNA | CTD | PMID:35436446 | fulvestrant | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ZSCAN18 gene | CTD | PMID:31601247 | geraniol | increases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | geraniol results in increased expression of ZSCAN18 mRNA | CTD | PMID:27683099 | methylmercury chloride | decreases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ZSCAN18 mRNA | CTD | PMID:28001369 | mitoxantrone | affects response to substance | ISO | ZSCAN18 (Homo sapiens) | 6480464 | ZSCAN18 protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 | ozone | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ZSCAN18 mRNA more ... | CTD | PMID:32699268 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ZSCAN18 mRNA | CTD | PMID:20813756 | pirinixic acid | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ZSCAN18 mRNA | CTD | PMID:19710929 | potassium chromate | increases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of ZSCAN18 mRNA | CTD | PMID:22714537 | SB 431542 | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenite | decreases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ZSCAN18 mRNA | CTD | PMID:34032870 | sunitinib | increases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ZSCAN18 mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | ISO | Zscan18 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of ZSCAN18 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases expression | ISO | Zscan18 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of ZSCAN18 mRNA | CTD | PMID:33387578 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of ZSCAN18 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | ISO | ZSCAN18 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ZSCAN18 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | ZSCAN18 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ZSCAN18 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ZSCAN18 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZSCAN18 mRNA | CTD | PMID:27188386 | |