Ttn (titin) - Rat Genome Database

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Gene: Ttn (titin) Mus musculus
Analyze
Symbol: Ttn
Name: titin
RGD ID: 1624066
MGI Page MGI
Description: Enables ankyrin binding activity. Involved in heart development; regulation of relaxation of cardiac muscle; and somitogenesis. Acts upstream of or within several processes, including forward locomotion; heart development; and sarcomere organization. Located in M band and Z disc. Is expressed in several structures, including alimentary system; embryo mesenchyme; heart; musculature; and tarsus. Used to study autosomal recessive limb-girdle muscular dystrophy type 2J; dilated cardiomyopathy 1G; and tibial muscular dystrophy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1100001C23Rik; 2310036G12Rik; 2310057K23Rik; 2310074I15Rik; AF006999; AV006427; conn; connectin; D330041I19Rik; D830007G01Rik; EST AF006999; L5; L56; mdm; sh; shru
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39276,534,324 - 76,812,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl276,534,324 - 76,812,891 (-)EnsemblGRCm39 Ensembl
GRCm38276,703,980 - 76,982,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl276,703,980 - 76,982,547 (-)EnsemblGRCm38mm10GRCm38
MGSCv37276,542,041 - 76,820,604 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36276,504,823 - 76,783,386 (-)NCBIMGSCv36mm8
Celera278,365,659 - 78,644,178 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map245.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
arrhythmogenic right ventricular cardiomyopathy  (ISO)
arrhythmogenic right ventricular dysplasia 1  (ISO)
arrhythmogenic right ventricular dysplasia 9  (ISO)
atrial fibrillation  (ISO)
autosomal recessive centronuclear myopathy  (ISO)
autosomal recessive limb-girdle muscular dystrophy  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2J  (IAGP,ISO)
Brugada syndrome  (ISO)
cardiac amyloidosis  (ISO)
cardiomyopathy  (ISO)
centronuclear myopathy  (ISO)
cerebral palsy  (ISO)
clubfoot  (ISO)
congenital muscular dystrophy  (ISO)
congenital myopathy  (ISO)
congenital myopathy 1B  (ISO)
congenital myopathy 5  (ISO)
congenital structural myopathy  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Diastolic Dysfunction  (ISO)
dilated cardiomyopathy  (ISO)
dilated cardiomyopathy 1A  (ISO)
dilated cardiomyopathy 1B  (ISO)
dilated cardiomyopathy 1G  (IAGP,ISO)
dilated cardiomyopathy 1H  (ISO)
dilated cardiomyopathy 1S  (ISO)
Dilated Cardiomyopathy with Left Ventricular Noncompaction  (ISO)
distal myopathy  (ISO)
Dwarfism  (ISO)
dystonia 16  (ISO)
Failure to Thrive  (ISO)
Familial Amyloid Polyneuropathies  (ISO)
familial hypertrophic cardiomyopathy  (ISO)
Gaucher's disease  (ISO)
Gaucher's disease type I  (ISO)
genetic disease  (ISO)
Heart Block  (ISO)
hypertrophic cardiomyopathy  (ISO)
hypertrophic cardiomyopathy 1  (ISO)
hypertrophic cardiomyopathy 9  (ISO)
Left Ventricular Hypertrophy  (ISO)
left ventricular noncompaction  (ISO)
Left Ventricular Noncompaction 2  (ISO)
leukocyte adhesion deficiency 1  (ISO)
limb-girdle muscular dystrophy  (ISO)
long QT syndrome  (ISO)
mitral valve prolapse  (ISO)
Muscle Hypotonia  (ISO)
Muscle Weakness  (ISO)
muscular disease  (ISO)
muscular dystrophy  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
myofibrillar myopathy 1  (ISO)
myofibrillar myopathy 9  (ISO)
myopathy  (ISO)
neuromuscular disease  (ISO)
orofacial cleft 1  (ISO)
restrictive cardiomyopathy  (ISO)
speech disorder  (ISO)
Sudden Cardiac Death  (ISO)
sudden infant death syndrome  (ISO)
Sudden Unexpected Nocturnal Death Syndrome  (ISO)
Supraventricular Tachycardia  (ISO)
Syncope  (ISO)
systolic heart failure  (ISO)
third-degree atrioventricular block  (ISO)
tibial muscular dystrophy  (IAGP,ISO)
transthyretin amyloidosis  (ISO)
Ventricular Fibrillation  (ISO)
Ventricular Premature Complexes  (ISO)
Ventricular Tachycardia  (ISO)
Wolff-Parkinson-White syndrome  (ISO)
X-linked Emery-Dreifuss muscular dystrophy 6  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (EXP)
acetylleucyl-leucyl-norleucinal  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Botulinum toxin type A  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
cantharidin  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
ciguatoxin CTX1B  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cylindrospermopsin  (ISO)
dexamethasone  (EXP)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (EXP,ISO)
diuron  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
glyphosate  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
microcystin-LR  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nitrogen dioxide  (ISO)
O-methyleugenol  (ISO)
paracetamol  (EXP)
phenethyl caffeate  (ISO)
pioglitazone  (EXP)
pirinixic acid  (EXP)
potassium cyanide  (EXP)
potassium dichromate  (EXP)
propiconazole  (EXP)
quercetin  (ISO)
resveratrol  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
spermine  (EXP)
sulforaphane  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
thalidomide  (EXP)
theophylline  (ISO)
titanium dioxide  (EXP)
triclosan  (ISO)
triptonide  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal angiogenesis  (IAGP)
abnormal blood circulation  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal cardiac muscle contractility  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal cardiovascular system morphology  (IEA)
abnormal diaphragm morphology  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal first pharyngeal arch morphology  (IAGP)
abnormal frontonasal mesenchyme morphology  (IAGP)
abnormal gait  (IAGP)
abnormal gastrocnemius morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart left atrium morphology  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal limb muscle morphology  (IAGP)
abnormal M line morphology  (IAGP)
abnormal muscle contractility  (IAGP)
abnormal muscle physiology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal posture  (IAGP)
abnormal quadriceps morphology  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal sarcomere morphology  (IAGP)
abnormal skeletal muscle morphology  (IAGP)
abnormal soleus morphology  (IAGP)
abnormal somite development  (IAGP)
abnormal tibialis anterior morphology  (IAGP)
abnormal vitelline vascular remodeling  (IAGP)
absent heartbeat  (IAGP)
absent organized vascular network  (IAGP)
blepharoptosis  (IAGP)
cardiac hypertrophy  (IAGP)
cardiac interstitial fibrosis  (IAGP)
cellular necrosis  (IAGP)
centrally nucleated skeletal muscle fibers  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased diastolic filling velocity  (IAGP)
decreased embryo size  (IAGP)
decreased heart weight  (IAGP)
decreased soleus weight  (IAGP)
decreased ventricle muscle contractility  (IAGP)
dilated cardiomyopathy  (IAGP)
dilated heart left ventricle  (IAGP)
dystrophic muscle  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
heart left ventricle hypertrophy  (IAGP)
hemorrhage  (IAGP)
hypoxia  (IAGP)
impaired exercise endurance  (IAGP)
impaired skeletal muscle contractility  (IAGP)
increased apoptosis  (IEA)
increased embryonic tissue cell apoptosis  (IAGP)
increased heart left atrium weight  (IAGP)
increased heart left ventricle size  (IAGP)
increased heart left ventricle weight  (IAGP)
increased left ventricle diastolic pressure  (IAGP)
increased left ventricle systolic pressure  (IAGP)
increased myocardial fiber size  (IAGP)
increased variability of skeletal muscle fiber size  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
microcephaly  (IAGP)
muscle degeneration  (IEA)
myositis  (IAGP)
no abnormal phenotype detected  (IAGP)
pericardial edema  (IAGP)
pericardial effusion  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
progressive muscle weakness  (IAGP)
skeletal muscle fiber atrophy  (IAGP)
skeletal muscle fiber necrosis  (IAGP)
thick ventricular wall  (IAGP)
thin myocardium  (IAGP)
trabecula carnea hypoplasia  (IAGP)
ventricular hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts. Makarenko I, etal., Circ Res. 2004 Oct 1;95(7):708-16. Epub 2004 Sep 2.
2. Titin isoform switch in ischemic human heart disease. Neagoe C, etal., Circulation. 2002 Sep 10;106(11):1333-41.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Titin-truncating variants affect heart function in disease cohorts and the general population. Schafer S, etal., Nat Genet. 2016 Nov 21. doi: 10.1038/ng.3719.
Additional References at PubMed
PMID:1582406   PMID:2129545   PMID:2203673   PMID:2680424   PMID:2693040   PMID:7720554   PMID:7720708   PMID:7896287   PMID:8307566   PMID:8359022   PMID:8486363   PMID:8604138  
PMID:8618961   PMID:8751373   PMID:9040657   PMID:9440711   PMID:9618202   PMID:9817758   PMID:10330145   PMID:10349636   PMID:10481174   PMID:10607827   PMID:10929709   PMID:11042159  
PMID:11044609   PMID:11076861   PMID:11130978   PMID:11217851   PMID:11544199   PMID:11717165   PMID:11829483   PMID:11956126   PMID:12355177   PMID:12464612   PMID:12466851   PMID:12477932  
PMID:12651156   PMID:14600266   PMID:14610273   PMID:14741210   PMID:15136139   PMID:15138196   PMID:15475267   PMID:15967462   PMID:16115818   PMID:16141072   PMID:16141073   PMID:16337936  
PMID:16470336   PMID:16481394   PMID:16702235   PMID:16717059   PMID:16881058   PMID:17038546   PMID:17261657   PMID:17360664   PMID:17522126   PMID:17664162   PMID:17904117   PMID:18310072  
PMID:18579686   PMID:18753318   PMID:18799693   PMID:18849322   PMID:19091769   PMID:19406126   PMID:19679835   PMID:19679839   PMID:19683008   PMID:19850579   PMID:20442316   PMID:20507834  
PMID:20855473   PMID:20860623   PMID:21041693   PMID:21255582   PMID:21267068   PMID:21289070   PMID:21327095   PMID:21536590   PMID:21555460   PMID:21565611   PMID:21659647   PMID:21677750  
PMID:21708170   PMID:21835910   PMID:21840390   PMID:21873635   PMID:21943419   PMID:22160926   PMID:22778266   PMID:22846424   PMID:23047121   PMID:23060211   PMID:23220127   PMID:23246787  
PMID:23266827   PMID:23283722   PMID:23297410   PMID:23709671   PMID:23824195   PMID:24457600   PMID:24470484   PMID:24470489   PMID:24500875   PMID:24565863   PMID:24599837   PMID:24603287  
PMID:24680892   PMID:24725620   PMID:24850911   PMID:24952961   PMID:24982444   PMID:25125171   PMID:25246556   PMID:25264194   PMID:25447537   PMID:25450617   PMID:25573826   PMID:25759365  
PMID:25877298   PMID:26039991   PMID:26075897   PMID:26272747   PMID:26394485   PMID:26504781   PMID:26682816   PMID:26708556   PMID:26944495   PMID:27120339   PMID:27171814   PMID:27470639  
PMID:27689697   PMID:27889803   PMID:27914791   PMID:27986994   PMID:27994045   PMID:28164238   PMID:28173117   PMID:28353642   PMID:28378742   PMID:28476659   PMID:28939561   PMID:29051486  
PMID:29078393   PMID:29360543   PMID:29978560   PMID:30121012   PMID:30475793   PMID:30523116   PMID:30550785   PMID:30565562   PMID:30567709   PMID:30700140   PMID:30713523   PMID:30987448  
PMID:31015287   PMID:31024170   PMID:31097600   PMID:31158359   PMID:31421188   PMID:31628386   PMID:31688894   PMID:31757849   PMID:31776291   PMID:31862847   PMID:32098917   PMID:32212902  
PMID:32345978   PMID:32376900   PMID:32492876   PMID:32547410   PMID:32561764   PMID:32619437   PMID:32900999   PMID:32929035   PMID:32994313   PMID:33357376   PMID:33397958   PMID:33414188  
PMID:33637999   PMID:33811919   PMID:33854441   PMID:34401916   PMID:34716659   PMID:35031281   PMID:35688153   PMID:35875854   PMID:36115951   PMID:36318802   PMID:36409887   PMID:36555335  
PMID:36871413   PMID:36899856   PMID:37019373   PMID:37414952   PMID:38158587   PMID:38381767  


Genomics

Comparative Map Data
Ttn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39276,534,324 - 76,812,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl276,534,324 - 76,812,891 (-)EnsemblGRCm39 Ensembl
GRCm38276,703,980 - 76,982,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl276,703,980 - 76,982,547 (-)EnsemblGRCm38mm10GRCm38
MGSCv37276,542,041 - 76,820,604 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36276,504,823 - 76,783,386 (-)NCBIMGSCv36mm8
Celera278,365,659 - 78,644,178 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map245.13NCBI
TTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382178,525,989 - 178,807,423 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2178,525,989 - 178,830,802 (-)EnsemblGRCh38hg38GRCh38
GRCh372179,390,716 - 179,672,150 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362179,098,962 - 179,380,395 (-)NCBINCBI36Build 36hg18NCBI36
Celera2172,993,600 - 173,266,525 (-)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2171,261,156 - 171,540,118 (-)NCBIHuRef
CHM1_12179,396,760 - 179,678,208 (-)NCBICHM1_1
T2T-CHM13v2.02179,008,783 - 179,290,485 (-)NCBIT2T-CHM13v2.0
Ttn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8382,059,648 - 82,332,130 (-)NCBIGRCr8
mRatBN7.2361,652,432 - 61,924,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0363,565,160 - 63,837,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0370,138,896 - 70,408,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4359,404,023 - 59,665,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1359,490,644 - 59,514,338 (-)NCBI
Celera361,137,881 - 61,409,292 (-)NCBICelera
Cytogenetic Map3q24NCBI
Ttn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540318,057,344 - 18,328,389 (+)NCBIChiLan1.0ChiLan1.0
TTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21381,172,170 - 81,452,915 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B81,187,144 - 81,467,889 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B65,783,512 - 66,064,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B183,487,352 - 183,767,268 (-)NCBIpanpan1.1PanPan1.1panPan2
TTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13622,146,870 - 22,417,858 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3622,147,824 - 22,417,826 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3622,165,230 - 22,439,415 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03622,290,643 - 22,564,715 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3622,291,570 - 22,564,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13622,399,838 - 22,673,559 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03622,362,753 - 22,636,976 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03622,479,043 - 22,752,940 (-)NCBIUU_Cfam_GSD_1.0
Ttn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303139,179,523 - 139,445,548 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365097,733,426 - 7,999,503 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11584,226,953 - 84,501,320 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21593,758,133 - 93,780,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11064,074,994 - 64,379,055 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1064,076,021 - 64,347,205 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040135,225,819 - 135,499,926 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624844484,593 - 760,155 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ttn
8067 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2899
Count of miRNA genes:740
Interacting mature miRNAs:972
Transcripts:ENSMUST00000011934, ENSMUST00000099980, ENSMUST00000099981, ENSMUST00000111846, ENSMUST00000111882, ENSMUST00000123448, ENSMUST00000123804, ENSMUST00000126515, ENSMUST00000128071, ENSMUST00000130915, ENSMUST00000134720, ENSMUST00000137854, ENSMUST00000138542, ENSMUST00000139832, ENSMUST00000140091, ENSMUST00000142251, ENSMUST00000147048, ENSMUST00000148747, ENSMUST00000149616, ENSMUST00000150741, ENSMUST00000151097, ENSMUST00000152185, ENSMUST00000155365, ENSMUST00000156257
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
4141069Pbwg1.5_mpostnatal body weight growth 1.5 (mouse)Not determined4352061277520756Mouse
1300788Cia2_mcollagen induced arthritis QTL 2 (mouse)Not determined24352061277520756Mouse
1300671Cia4_mcollagen induced arthritis QTL 4 (mouse)Not determined24352061277520756Mouse
1301402Ap2q_malcohol preference 2 QTL (mouse)Not determined24352061277520756Mouse
1301411Pitm1_mprion incubation time 1 (mouse)Not determined24352061277520756Mouse
10755532Lymph5_mlymphocyte differential 5 (mouse)24419901778199017Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11532740Pbwg1.10_mpostnatal body weight growth 1.10 (mouse)24813241282132495Mouse
1558820Moo1_mmodifier of Odc1 (mouse)Not determined174826974682269934Mouse
1301747Eae21_mexperimental allergic encephalomyelitis 21 (mouse)Not determined24826974682269934Mouse
1301235Alcw4_malcohol withdrawal 4 (mouse)Not determined24826974682269934Mouse
1300568Hdl1_mhigh density lipoprotein (HDL) level 1 (mouse)Not determined24826974682269934Mouse
10755526Lymph1_mlymphocyte differential 1 (mouse)25081931484819314Mouse
1300875Taste1_mtaste-saccharin preference 1 (mouse)Not determined25092317584923278Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25170327685703425Mouse
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse

Markers in Region
27.MMHAP20FRA12.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,791,278 - 76,791,460UniSTSGRCm38
MGSCv37276,629,335 - 76,629,517UniSTSGRCm37
Celera278,452,953 - 78,453,135UniSTS
Cytogenetic Map2DUniSTS
cM Map244.0UniSTS
Whitehead_YAC2 UniSTS
D2Mit158  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,984,002 - 76,984,148UniSTSGRCm38
MGSCv37276,822,059 - 76,822,205UniSTSGRCm37
Celera278,645,633 - 78,645,779UniSTS
Cytogenetic Map2DUniSTS
cM Map245.5UniSTS
Whitehead Genetic244.8UniSTS
Whitehead_YAC2 UniSTS
D2Mit93  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,848,414 - 76,848,554UniSTSGRCm38
MGSCv37276,686,471 - 76,686,611UniSTSGRCm37
Celera278,510,091 - 78,510,231UniSTS
Cytogenetic Map2DUniSTS
cM Map246.0UniSTS
Whitehead Genetic244.8UniSTS
Whitehead_YAC2 UniSTS
Ttn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37276,812,248 - 76,812,456UniSTSGRCm37
Celera278,635,816 - 78,636,024UniSTS
Cytogenetic Map2DUniSTS
cM Map244.0UniSTS
RH126352  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,934,732 - 76,934,971UniSTSGRCm38
MGSCv37276,772,789 - 76,773,028UniSTSGRCm37
Celera278,596,405 - 78,596,644UniSTS
Cytogenetic Map2DUniSTS
cM Map244.0UniSTS
Whitehead/MRC_RH21206.39UniSTS
AV006427  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,704,231 - 76,704,362UniSTSGRCm38
MGSCv37276,542,288 - 76,542,419UniSTSGRCm37
Celera278,365,906 - 78,366,037UniSTS
Cytogenetic Map2DUniSTS
cM Map244.0UniSTS
MARC_21540-21541:1033053987:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,733,950 - 76,734,192UniSTSGRCm38
MGSCv37276,572,007 - 76,572,249UniSTSGRCm37
Celera278,395,625 - 78,395,867UniSTS
Cytogenetic Map2DUniSTS
cM Map244.0UniSTS
D2Ucl5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,963,920 - 76,964,151UniSTSGRCm38
MGSCv37276,801,977 - 76,802,208UniSTSGRCm37
Celera278,625,455 - 78,625,686UniSTS
Cytogenetic Map2DUniSTS
cM Map263.8UniSTS
RH98821  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,727,041 - 76,727,180UniSTSGRCm38
MGSCv37276,565,098 - 76,565,237UniSTSGRCm37
Celera278,388,716 - 78,388,855UniSTS
Cytogenetic Map2DUniSTS
cM Map244.0UniSTS
Ttn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38276,974,191 - 76,974,399UniSTSGRCm38
MGSCv37276,812,248 - 76,812,456UniSTSGRCm37
Celera278,635,816 - 78,636,024UniSTS
Cytogenetic Map2DUniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001385708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_028004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB100271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF426841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL928681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL928721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL928789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB532149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB662000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG795347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BN001114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000011934   ⟹   ENSMUSP00000011934
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,534,324 - 76,812,799 (-)Ensembl
GRCm38.p6 Ensembl276,703,980 - 76,982,455 (-)Ensembl
RefSeq Acc Id: ENSMUST00000099980   ⟹   ENSMUSP00000097560
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,744,288 - 76,812,799 (-)Ensembl
GRCm38.p6 Ensembl276,913,944 - 76,982,455 (-)Ensembl
RefSeq Acc Id: ENSMUST00000099981   ⟹   ENSMUSP00000097561
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,534,324 - 76,812,799 (-)Ensembl
GRCm38.p6 Ensembl276,703,980 - 76,982,455 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111846   ⟹   ENSMUSP00000107477
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,535,375 - 76,810,526 (-)Ensembl
GRCm38.p6 Ensembl276,705,031 - 76,980,182 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111882   ⟹   ENSMUSP00000107513
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,534,328 - 76,812,891 (-)Ensembl
GRCm38.p6 Ensembl276,703,984 - 76,982,547 (-)Ensembl
RefSeq Acc Id: ENSMUST00000123448
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,766,268 - 76,768,868 (-)Ensembl
GRCm38.p6 Ensembl276,935,924 - 76,938,524 (-)Ensembl
RefSeq Acc Id: ENSMUST00000123804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,794,634 - 76,812,891 (-)Ensembl
GRCm38.p6 Ensembl276,964,290 - 76,982,547 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126515   ⟹   ENSMUSP00000119089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,674,577 - 76,677,514 (-)Ensembl
GRCm38.p6 Ensembl276,844,233 - 76,847,170 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128071   ⟹   ENSMUSP00000118602
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,645,121 - 76,698,733 (-)Ensembl
GRCm38.p6 Ensembl276,814,777 - 76,868,389 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130915   ⟹   ENSMUSP00000115190
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,645,103 - 76,698,733 (-)Ensembl
GRCm38.p6 Ensembl276,814,759 - 76,868,389 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134720   ⟹   ENSMUSP00000116594
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,644,560 - 76,762,584 (-)Ensembl
GRCm38.p6 Ensembl276,814,216 - 76,932,240 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137854   ⟹   ENSMUSP00000117059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,652,874 - 76,671,497 (-)Ensembl
GRCm38.p6 Ensembl276,822,530 - 76,841,153 (-)Ensembl
RefSeq Acc Id: ENSMUST00000138542   ⟹   ENSMUSP00000116031
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,679,615 - 76,700,955 (-)Ensembl
GRCm38.p6 Ensembl276,849,271 - 76,870,611 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139832
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,719,095 - 76,719,851 (-)Ensembl
GRCm38.p6 Ensembl276,888,751 - 76,889,507 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140091   ⟹   ENSMUSP00000122470
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,795,440 - 76,812,891 (-)Ensembl
GRCm38.p6 Ensembl276,965,096 - 76,982,547 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142251   ⟹   ENSMUSP00000119894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,651,475 - 76,656,886 (-)Ensembl
GRCm38.p6 Ensembl276,821,131 - 76,826,542 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147048
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,803,401 - 76,812,891 (-)Ensembl
GRCm38.p6 Ensembl276,973,057 - 76,982,547 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148747   ⟹   ENSMUSP00000117447
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,645,068 - 76,720,269 (-)Ensembl
GRCm38.p6 Ensembl276,814,724 - 76,889,925 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149616   ⟹   ENSMUSP00000123202
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,645,102 - 76,698,733 (-)Ensembl
GRCm38.p6 Ensembl276,814,758 - 76,868,389 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150741   ⟹   ENSMUSP00000117534
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,662,492 - 76,663,451 (-)Ensembl
GRCm38.p6 Ensembl276,832,148 - 76,833,107 (-)Ensembl
RefSeq Acc Id: ENSMUST00000151097   ⟹   ENSMUSP00000118209
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,666,309 - 76,669,240 (-)Ensembl
GRCm38.p6 Ensembl276,835,965 - 76,838,896 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152185   ⟹   ENSMUSP00000118492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,645,103 - 76,698,733 (-)Ensembl
GRCm38.p6 Ensembl276,814,759 - 76,868,389 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155365   ⟹   ENSMUSP00000121095
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,645,103 - 76,698,733 (-)Ensembl
GRCm38.p6 Ensembl276,814,759 - 76,868,389 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156257   ⟹   ENSMUSP00000114666
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,661,717 - 76,662,640 (-)Ensembl
GRCm38.p6 Ensembl276,831,373 - 76,832,296 (-)Ensembl
RefSeq Acc Id: ENSMUST00000190813   ⟹   ENSMUSP00000140714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl276,666,309 - 76,667,158 (-)Ensembl
GRCm38.p6 Ensembl276,835,965 - 76,836,814 (-)Ensembl
RefSeq Acc Id: NM_001385708   ⟹   NP_001372637
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,890 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011652   ⟹   NP_035782
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,328 - 76,812,891 (-)NCBI
GRCm38276,703,984 - 76,982,547 (-)NCBI
MGSCv37276,542,041 - 76,820,604 (-)RGD
Celera278,365,659 - 78,644,178 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_028004   ⟹   NP_082280
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,328 - 76,812,891 (-)NCBI
GRCm38276,703,984 - 76,982,547 (-)NCBI
MGSCv37276,542,041 - 76,820,604 (-)RGD
Celera278,365,659 - 78,644,178 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036160520   ⟹   XP_036016413
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160524   ⟹   XP_036016417
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160527   ⟹   XP_036016420
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160528   ⟹   XP_036016421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160529   ⟹   XP_036016422
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160534   ⟹   XP_036016427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160535   ⟹   XP_036016428
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160536   ⟹   XP_036016429
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160537   ⟹   XP_036016430
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160538   ⟹   XP_036016431
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,812,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160540   ⟹   XP_036016433
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,534,324 - 76,654,846 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160543   ⟹   XP_036016436
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39276,741,137 - 76,812,901 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001372637 (Get FASTA)   NCBI Sequence Viewer  
  NP_035782 (Get FASTA)   NCBI Sequence Viewer  
  NP_082280 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016413 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016417 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016420 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016421 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016422 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016427 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016428 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016429 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016430 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016431 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016433 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016436 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A2ASS6 (Get FASTA)   NCBI Sequence Viewer  
  AAH25840 (Get FASTA)   NCBI Sequence Viewer  
  AAL84320 (Get FASTA)   NCBI Sequence Viewer  
  AAL84321 (Get FASTA)   NCBI Sequence Viewer  
  AAL84322 (Get FASTA)   NCBI Sequence Viewer  
  BAB22606 (Get FASTA)   NCBI Sequence Viewer  
  BAB26413 (Get FASTA)   NCBI Sequence Viewer  
  BAB26738 (Get FASTA)   NCBI Sequence Viewer  
  BAC26249 (Get FASTA)   NCBI Sequence Viewer  
  BAC28957 (Get FASTA)   NCBI Sequence Viewer  
  BAC33179 (Get FASTA)   NCBI Sequence Viewer  
  BAC35178 (Get FASTA)   NCBI Sequence Viewer  
  BAC38363 (Get FASTA)   NCBI Sequence Viewer  
  BAC39259 (Get FASTA)   NCBI Sequence Viewer  
  BAC39277 (Get FASTA)   NCBI Sequence Viewer  
  BAC39538 (Get FASTA)   NCBI Sequence Viewer  
  BAC39548 (Get FASTA)   NCBI Sequence Viewer  
  BAC55524 (Get FASTA)   NCBI Sequence Viewer  
  BAE24132 (Get FASTA)   NCBI Sequence Viewer  
  BAE25205 (Get FASTA)   NCBI Sequence Viewer  
  BAE34195 (Get FASTA)   NCBI Sequence Viewer  
  CAA45941 (Get FASTA)   NCBI Sequence Viewer  
  EDL27217 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000011934
  ENSMUSP00000011934.7
  ENSMUSP00000097560
  ENSMUSP00000097560.4
  ENSMUSP00000097561
  ENSMUSP00000097561.4
  ENSMUSP00000107477
  ENSMUSP00000107477.3
  ENSMUSP00000107513.3
  ENSMUSP00000114666.2
  ENSMUSP00000115190.2
  ENSMUSP00000116031.2
  ENSMUSP00000116594.2
  ENSMUSP00000117059.2
  ENSMUSP00000117447.2
  ENSMUSP00000117534.2
  ENSMUSP00000118209.2
  ENSMUSP00000118492.2
  ENSMUSP00000118602.2
  ENSMUSP00000119089.2
  ENSMUSP00000119894.2
  ENSMUSP00000121095.2
  ENSMUSP00000122470.2
  ENSMUSP00000123202.2
  ENSMUSP00000140714.2
Reference Protein Sequences
RefSeq Acc Id: NP_082280   ⟸   NM_028004
- Peptide Label: isoform N2-B
- UniProtKB: A0A5K1VVQ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_035782   ⟸   NM_011652
- Peptide Label: isoform N2-A
- UniProtKB: E9Q8N1 (UniProtKB/TrEMBL),   E9Q8K5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000117534   ⟸   ENSMUST00000150741
RefSeq Acc Id: ENSMUSP00000107477   ⟸   ENSMUST00000111846
RefSeq Acc Id: ENSMUSP00000107513   ⟸   ENSMUST00000111882
RefSeq Acc Id: ENSMUSP00000115190   ⟸   ENSMUST00000130915
RefSeq Acc Id: ENSMUSP00000116031   ⟸   ENSMUST00000138542
RefSeq Acc Id: ENSMUSP00000097560   ⟸   ENSMUST00000099980
RefSeq Acc Id: ENSMUSP00000097561   ⟸   ENSMUST00000099981
RefSeq Acc Id: ENSMUSP00000011934   ⟸   ENSMUST00000011934
RefSeq Acc Id: ENSMUSP00000118492   ⟸   ENSMUST00000152185
RefSeq Acc Id: ENSMUSP00000119089   ⟸   ENSMUST00000126515
RefSeq Acc Id: ENSMUSP00000118209   ⟸   ENSMUST00000151097
RefSeq Acc Id: ENSMUSP00000140714   ⟸   ENSMUST00000190813
RefSeq Acc Id: ENSMUSP00000123202   ⟸   ENSMUST00000149616
RefSeq Acc Id: ENSMUSP00000122470   ⟸   ENSMUST00000140091
RefSeq Acc Id: ENSMUSP00000116594   ⟸   ENSMUST00000134720
RefSeq Acc Id: ENSMUSP00000117447   ⟸   ENSMUST00000148747
RefSeq Acc Id: ENSMUSP00000118602   ⟸   ENSMUST00000128071
RefSeq Acc Id: ENSMUSP00000117059   ⟸   ENSMUST00000137854
RefSeq Acc Id: ENSMUSP00000119894   ⟸   ENSMUST00000142251
RefSeq Acc Id: ENSMUSP00000114666   ⟸   ENSMUST00000156257
RefSeq Acc Id: ENSMUSP00000121095   ⟸   ENSMUST00000155365
RefSeq Acc Id: XP_036016431   ⟸   XM_036160538
- Peptide Label: isoform X10
- UniProtKB: A0A5K1VVQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016430   ⟸   XM_036160537
- Peptide Label: isoform X9
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016429   ⟸   XM_036160536
- Peptide Label: isoform X8
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016428   ⟸   XM_036160535
- Peptide Label: isoform X7
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016427   ⟸   XM_036160534
- Peptide Label: isoform X6
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016422   ⟸   XM_036160529
- Peptide Label: isoform X5
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016421   ⟸   XM_036160528
- Peptide Label: isoform X4
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016420   ⟸   XM_036160527
- Peptide Label: isoform X3
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016417   ⟸   XM_036160524
- Peptide Label: isoform X2
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016413   ⟸   XM_036160520
- Peptide Label: isoform X1
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001372637   ⟸   NM_001385708
- Peptide Label: isoform 3
- UniProtKB: A0A5K1VVQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016433   ⟸   XM_036160540
- Peptide Label: isoform X11
- UniProtKB: A0A5K1VVQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016436   ⟸   XM_036160543
- Peptide Label: isoform X12
Protein Domains
Fibronectin type-III   Ig-like   Immunoglobulin I-set   Protein kinase   Reverse transcriptase

Promoters
RGD ID:6877712
Promoter ID:EPDNEW_M2307
Type:multiple initiation site
Name:Ttn_1
Description:Mus musculus titin , transcript variant N2-B, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38276,982,546 - 76,982,606EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98864 AgrOrtholog
Ensembl Genes ENSMUSG00000051747 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000011934 ENTREZGENE
  ENSMUST00000011934.13 UniProtKB/TrEMBL
  ENSMUST00000099980 ENTREZGENE
  ENSMUST00000099980.10 UniProtKB/Swiss-Prot
  ENSMUST00000099981 ENTREZGENE
  ENSMUST00000099981.10 UniProtKB/TrEMBL
  ENSMUST00000111846 ENTREZGENE
  ENSMUST00000111846.9 UniProtKB/TrEMBL
  ENSMUST00000111882.9 UniProtKB/TrEMBL
  ENSMUST00000126515.2 UniProtKB/TrEMBL
  ENSMUST00000128071.8 UniProtKB/TrEMBL
  ENSMUST00000130915.8 UniProtKB/TrEMBL
  ENSMUST00000134720.8 UniProtKB/TrEMBL
  ENSMUST00000137854.8 UniProtKB/TrEMBL
  ENSMUST00000138542.2 UniProtKB/TrEMBL
  ENSMUST00000140091.8 UniProtKB/TrEMBL
  ENSMUST00000142251.8 UniProtKB/TrEMBL
  ENSMUST00000148747.8 UniProtKB/TrEMBL
  ENSMUST00000149616.8 UniProtKB/TrEMBL
  ENSMUST00000150741.2 UniProtKB/TrEMBL
  ENSMUST00000151097.8 UniProtKB/TrEMBL
  ENSMUST00000152185.8 UniProtKB/TrEMBL
  ENSMUST00000155365.8 UniProtKB/TrEMBL
  ENSMUST00000156257.2 UniProtKB/TrEMBL
  ENSMUST00000190813.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MyBP-C_THB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PPAK_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RT_dom UniProtKB/TrEMBL
  Titin_Z_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98864 ENTREZGENE
NCBI Gene 22138 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN UniProtKB/TrEMBL
  IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  IMMUNOGLOBULIN UniProtKB/TrEMBL
  MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 UniProtKB/Swiss-Prot
  MYOPALLADIN ISOFORM X1 UniProtKB/TrEMBL
  MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE UniProtKB/TrEMBL
  NEURAL CELL ADHESION MOLECULE UniProtKB/TrEMBL
  PTHR14340 UniProtKB/TrEMBL
  PTHR14340:SF24 UniProtKB/TrEMBL
  REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  SI:DKEY-31G6.6 UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
  WRAPPER_REGA-1_KLINGON HOMOLOG UniProtKB/TrEMBL
Pfam fn3; 132 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PPAK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RVT_1 UniProtKB/TrEMBL
  THB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Titin_Z UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ttn PhenoGen
PRINTS FNTYPEIII UniProtKB/TrEMBL
  PRICHEXTENSN UniProtKB/TrEMBL
PROSITE FN3; 132 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  RT_POL UniProtKB/TrEMBL
SMART FN3; 132 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WRP0_MOUSE UniProtKB/TrEMBL
  A0A5K1VVQ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A5K1VVQ9 ENTREZGENE, UniProtKB/TrEMBL
  A2ASS6 ENTREZGENE
  A2AT61_MOUSE UniProtKB/TrEMBL
  A2AT62_MOUSE UniProtKB/TrEMBL
  A2AT63_MOUSE UniProtKB/TrEMBL
  A2AT64_MOUSE UniProtKB/TrEMBL
  A2AT65_MOUSE UniProtKB/TrEMBL
  A2AT66_MOUSE UniProtKB/TrEMBL
  A2AT67_MOUSE UniProtKB/TrEMBL
  A2AT68_MOUSE UniProtKB/TrEMBL
  A2AT70_MOUSE UniProtKB/TrEMBL
  E9Q8K5 ENTREZGENE, UniProtKB/TrEMBL
  E9Q8N1 ENTREZGENE, UniProtKB/TrEMBL
  F6Q6Z0_MOUSE UniProtKB/TrEMBL
  F6RSJ3_MOUSE UniProtKB/TrEMBL
  F6ZRX7_MOUSE UniProtKB/TrEMBL
  F6ZZ75_MOUSE UniProtKB/TrEMBL
  F7CR78_MOUSE UniProtKB/TrEMBL
  Q3TZL3_MOUSE UniProtKB/TrEMBL
  Q3UT48_MOUSE UniProtKB/TrEMBL
  Q812E1_MOUSE UniProtKB/TrEMBL
  Q8BID4_MOUSE UniProtKB/TrEMBL
  Q8BIH3_MOUSE UniProtKB/TrEMBL
  Q8BM32_MOUSE UniProtKB/TrEMBL
  Q8BUC9_MOUSE UniProtKB/TrEMBL
  Q8BUJ0_MOUSE UniProtKB/TrEMBL
  Q8BUJ6_MOUSE UniProtKB/TrEMBL
  Q8BUX4_MOUSE UniProtKB/TrEMBL
  Q8C139_MOUSE UniProtKB/TrEMBL
  Q8R112_MOUSE UniProtKB/TrEMBL
  Q8R4N1_MOUSE UniProtKB/TrEMBL
  Q8R4N2_MOUSE UniProtKB/TrEMBL
  Q8R4N3_MOUSE UniProtKB/TrEMBL
  Q9CTL3_MOUSE UniProtKB/TrEMBL
  Q9CV48_MOUSE UniProtKB/TrEMBL
  Q9D6N4_MOUSE UniProtKB/TrEMBL
  TITIN_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A2ASS5 UniProtKB/Swiss-Prot
  A2ASS7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-28 Ttn  titin  AF006999  EST AF006999  Data merged from RGD:1613657 737654 PROVISIONAL