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Gene: Elane (elastase, neutrophil expressed) Mus musculus
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Symbol: Elane
Name: elastase, neutrophil expressed
Description: Exhibits serine-type endopeptidase activity. Involved in several processes, including acute inflammatory response to antigenic stimulus; response to fungus; and response to lipopolysaccharide. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in cyclic hematopoiesis; periodontitis; polycythemia vera; and severe congenital neutropenia. Orthologous to human ELANE (elastase, neutrophil expressed).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ela2; elastase 2, neutrophil; elastase-2; F430011M15Rik; leukocyte elastase; NE; neutrophil elastase
Orthologs:
Homo sapiens (human) : ELANE (elastase, neutrophil expressed)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Elane (elastase, neutrophil expressed)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ELANE (elastase, neutrophil expressed)
Canis lupus familiaris (dog) : ELANE (elastase, neutrophil expressed)
Sus scrofa (pig) : ELANE (elastase, neutrophil expressed)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381079,886,312 - 79,888,216 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371079,349,057 - 79,350,961 (+)NCBIGRCm37mm9NCBIm37
MGSCv361079,289,464 - 79,291,246 (+)NCBImm8
Celera1080,901,123 - 80,903,026 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Elane
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1624045
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-10-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.