Krtap5-4 (keratin associated protein 5-4) - Rat Genome Database

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Gene: Krtap5-4 (keratin associated protein 5-4) Mus musculus
Analyze
No known orthologs.
Symbol: Krtap5-4
Name: keratin associated protein 5-4
RGD ID: 1624037
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Predicted to be located in keratin filament. Is expressed in skin. Orthologous to several human genes including KRTAP5-10 (keratin associated protein 5-10); KRTAP5-11 (keratin associated protein 5-11); and KRTAP5-2 (keratin associated protein 5-2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: keratin-associated protein 5-4; UHS-Ser-2; ultra high sulfur serine protein 2
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,857,239 - 141,858,240 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,857,286 - 141,858,331 (+)EnsemblGRCm39 Ensembl
GRCm387142,303,502 - 142,304,503 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7142,303,549 - 142,304,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv377149,489,407 - 149,490,408 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367142,112,985 - 142,113,656 (+)NCBIMGSCv36mm8
Celera7142,058,738 - 142,059,739 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1840598   PMID:2250030   PMID:12466851   PMID:18721477   PMID:19470461  


Genomics

Variants

.
Variants in Krtap5-4
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:114
Interacting mature miRNAs:116
Transcripts:ENSMUST00000061403
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse

Markers in Region
Krtap5-4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387142,304,276 - 142,304,386UniSTSGRCm38
Celera7142,059,512 - 142,059,622UniSTS
Cytogenetic Map7F5UniSTS
cM Map787.87UniSTS
UniSTS:485260  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387142,303,595 - 142,304,266UniSTSGRCm38
GRCm387142,156,454 - 142,157,113UniSTSGRCm38
MGSCv377149,489,500 - 149,490,171UniSTSGRCm37
MGSCv377149,342,359 - 149,343,018UniSTSGRCm37
Celera7142,058,831 - 142,059,502UniSTS
Celera7141,910,944 - 141,911,603UniSTS
Cytogenetic Map7F5UniSTS
UniSTS:495512  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387142,303,513 - 142,304,304UniSTSGRCm38
MGSCv377149,489,418 - 149,490,209UniSTSGRCm37
Celera7142,058,749 - 142,059,540UniSTS
Cytogenetic Map7F5UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000061403   ⟹   ENSMUSP00000059461
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,857,286 - 141,858,331 (+)Ensembl
GRCm38.p6 Ensembl7142,303,549 - 142,304,594 (+)Ensembl
RefSeq Acc Id: NM_015809   ⟹   NP_056624
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,857,239 - 141,858,240 (+)NCBI
GRCm387142,303,502 - 142,304,503 (+)ENTREZGENE
MGSCv377149,489,407 - 149,490,408 (+)RGD
Celera7142,058,738 - 142,059,739 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_056624 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40107 (Get FASTA)   NCBI Sequence Viewer  
  EDL18140 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000059461
  ENSMUSP00000059461.5
GenBank Protein Q62220 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_056624   ⟸   NM_015809
- UniProtKB: Q62220 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000059461   ⟸   ENSMUST00000061403

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62220-F1-model_v2 AlphaFold Q62220 1-223 view protein structure

Promoters
RGD ID:8666185
Promoter ID:EPDNEW_M11124
Type:multiple initiation site
Name:Krtap5-4_1
Description:Mus musculus keratin associated protein 5-4 (Krtap5-4), mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387142,303,540 - 142,303,600EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354758 AgrOrtholog
Ensembl Genes ENSMUSG00000045236 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000061403 ENTREZGENE
  ENSMUST00000061403.6 UniProtKB/Swiss-Prot
InterPro KAP UniProtKB/Swiss-Prot
KEGG Report mmu:50775 UniProtKB/Swiss-Prot
MGD MGI:1354758 ENTREZGENE
NCBI Gene 50775 ENTREZGENE
Pfam Keratin_B2_2 UniProtKB/Swiss-Prot
PhenoGen Krtap5-4 PhenoGen
UniProt KRA54_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE