Eid3 (EP300 interacting inhibitor of differentiation 3) - Rat Genome Database
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Gene: Eid3 (EP300 interacting inhibitor of differentiation 3) Mus musculus
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Symbol: Eid3
Name: EP300 interacting inhibitor of differentiation 3
RGD ID: 1624005
Description: Predicted to be involved in DNA repair and positive regulation of response to DNA damage stimulus. Predicted to localize to Smc5-Smc6 complex; nucleolus; and nucleoplasm. Orthologous to human EID3 (EP300 interacting inhibitor of differentiation 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxynon-2-enal; andrographolide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700027M21Rik; EID-1-like inhibitor of differentiation 3; EID-3; EP300-interacting inhibitor of differentiation 3; MGC118226; non-SMC element 4 homolog B; non-structural maintenance of chromosomes element 4 homolog B; NS4EB
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391082,702,460 - 82,703,764 (+)NCBI
GRCm381082,866,626 - 82,867,930 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1082,866,626 - 82,867,930 (+)EnsemblGRCm38mm10GRCm38
MGSCv371082,329,371 - 82,330,675 (+)NCBIGRCm37mm9NCBIm37
MGSCv361082,296,457 - 82,297,726 (+)NCBImm8
Celera1084,851,342 - 84,852,646 (+)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15987788   PMID:16141072   PMID:16141073   PMID:21364888   PMID:21873635   PMID:32325033  


Genomics

Comparative Map Data
Eid3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391082,702,460 - 82,703,764 (+)NCBI
GRCm381082,866,626 - 82,867,930 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1082,866,626 - 82,867,930 (+)EnsemblGRCm38mm10GRCm38
MGSCv371082,329,371 - 82,330,675 (+)NCBIGRCm37mm9NCBIm37
MGSCv361082,296,457 - 82,297,726 (+)NCBImm8
Celera1084,851,342 - 84,852,646 (+)NCBICelera
Cytogenetic Map10C1NCBI
EID3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12104,303,739 - 104,305,205 (+)EnsemblGRCh38hg38GRCh38
GRCh3812104,303,739 - 104,305,205 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712104,697,510 - 104,698,983 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612103,221,679 - 103,223,113 (+)NCBINCBI36hg18NCBI36
Celera12104,361,247 - 104,362,681 (+)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12101,757,788 - 101,759,261 (+)NCBIHuRef
CHM1_112104,663,356 - 104,664,829 (+)NCBICHM1_1
Eid3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0726,976,154 - 26,977,479 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0727,095,849 - 27,097,174 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,085,569 - 23,086,894 (-)NCBIRGSC3.4rn4RGSC3.4
Celera718,039,933 - 18,041,258 (-)NCBICelera
Cytogenetic Map7q13NCBI
Eid3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540538,897,494 - 38,898,057 (+)NCBIChiLan1.0ChiLan1.0
EID3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11033,955,843 - 33,957,527 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Eid3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649210,232,140 - 10,233,557 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EID3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1580,221,334 - 80,234,567 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2583,725,886 - 83,727,438 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Eid3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247504,478,753 - 4,482,276 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101023252187565233Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101282830784243920Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101282830784243920Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101282830784243920Mouse
1357893Lvrq4_mliver weight QTL 4 (mouse)Not determined101282830784243920Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1282830784243920Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1282830784243920Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1282830784243920Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1282830784243920Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101282830784243920Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1045000000116100000Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045600000120800000Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104950223383502378Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined105001240884012633Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined105001240884012633Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined105001240884012633Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined105001244384012618Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined105001244384012618Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105125566085255809Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105125566085255809Mouse
14746991Manh68_mmandible shape 68 (mouse)105244466786444667Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105868113592681262Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
13208560Wght9_mweight 9 (mouse)1060000000121000000Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1064100000116100000Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106565510499655287Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106565510499655287Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106565510499655287Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106701240892422811Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067500000111900000Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073671039107671185Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075502706109502905Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75502706109502905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075502706109502905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078545406112545406Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082242550116242550Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082473556116473795Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082473556116473795Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082473556116473795Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082473556116473795Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082473556116473795Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082473556116473795Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082556941116557090Mouse
4141382Ssrq4_mstress response QTL 4 (mouse)Not determined8265510491020240Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000211623   ⟹   ENSMUSP00000147261
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1082,866,626 - 82,867,930 (+)Ensembl
RefSeq Acc Id: NM_025499   ⟹   NP_079775
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391082,702,460 - 82,703,764 (+)NCBI
GRCm381082,866,626 - 82,867,930 (+)ENTREZGENE
MGSCv371082,329,371 - 82,330,675 (+)RGD
Celera1084,851,342 - 84,852,646 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079775   ⟸   NM_025499
- UniProtKB: Q3V124 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000147261   ⟸   ENSMUST00000211623

Promoters
RGD ID:6819228
Promoter ID:MM_KWN:5107
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   MEF_B6
Transcripts:NM_025499
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361082,328,696 - 82,330,387 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913591 AgrOrtholog
Ensembl Genes ENSMUSG00000109864 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000147261 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000211623 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Nse4/EID UniProtKB/Swiss-Prot
  Nse4_C UniProtKB/Swiss-Prot
  Nse4_Nse3-bd UniProtKB/Swiss-Prot
KEGG Report mmu:66341 UniProtKB/Swiss-Prot
MGD MGI:1913591 ENTREZGENE
NCBI Gene 66341 ENTREZGENE
PANTHER PTHR16140 UniProtKB/Swiss-Prot
Pfam Nse4-Nse3_bdg UniProtKB/Swiss-Prot
  Nse4_C UniProtKB/Swiss-Prot
PhenoGen Eid3 PhenoGen
UniGene Mm.443284 ENTREZGENE
UniProt EID3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3TTL4 UniProtKB/Swiss-Prot
  Q4KL03 UniProtKB/Swiss-Prot
  Q8CF34 UniProtKB/Swiss-Prot
  Q9CVN8 UniProtKB/Swiss-Prot