Cfap144 (cilia and flagella associated protein 144) - Rat Genome Database

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Gene: Cfap144 (cilia and flagella associated protein 144) Mus musculus
Analyze
Symbol: Cfap144 (Ensembl: Fam183b)
Name: cilia and flagella associated protein 144 (Ensembl:family with sequence similarity 183, member B)
RGD ID: 1623919
MGI Page MGI
Description: Predicted to enable microtubule binding activity. Located in centrosome and ciliary basal body. Is active in axonemal B tubule inner sheath and ciliary base. Is expressed in several structures, including brain ventricle and choroid plexus; gonad; notochord; respiratory system; and sensory organ. Orthologous to several human genes including CFAP144 (cilia and flagella associated protein 144).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3100002J23Rik; Fam183b; family with sequence similarity 183, member B; hypothetical protein LOC75429; MGC143784; RP23-419P16.2; testis highly expressed protein 6; Theg6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,683,628 - 58,692,786 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,683,623 - 58,692,786 (-)EnsemblGRCm39 Ensembl
GRCm381158,783,892 - 58,802,221 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,792,797 - 58,801,960 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,606,304 - 58,615,462 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,608,997 - 58,618,212 (-)NCBIMGSCv36mm8
MGSCv361159,323,707 - 59,346,798 (-)NCBIMGSCv36mm8
Celera1163,555,369 - 63,564,441 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:22008794  
PMID:27914912   PMID:29992973   PMID:30279523   PMID:37295417  


Genomics

Comparative Map Data
Cfap144
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,683,628 - 58,692,786 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,683,623 - 58,692,786 (-)EnsemblGRCm39 Ensembl
GRCm381158,783,892 - 58,802,221 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,792,797 - 58,801,960 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,606,304 - 58,615,462 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,608,997 - 58,618,212 (-)NCBIMGSCv36mm8
MGSCv361159,323,707 - 59,346,798 (-)NCBIMGSCv36mm8
Celera1163,555,369 - 63,564,441 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.3NCBI
CFAP144
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38143,142,962 - 43,156,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl143,145,153 - 43,156,396 (+)EnsemblGRCh38hg38GRCh38
GRCh37143,613,575 - 43,622,067 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36143,386,181 - 43,394,654 (+)NCBINCBI36Build 36hg18NCBI36
Celera141,895,704 - 41,904,179 (+)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef141,733,354 - 41,741,829 (+)NCBIHuRef
CHM1_1143,730,108 - 43,738,534 (+)NCBICHM1_1
T2T-CHM13v2.0142,998,069 - 43,026,887 (+)NCBIT2T-CHM13v2.0
Cfap144
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81044,009,412 - 44,019,281 (-)NCBIGRCr8
mRatBN7.21043,509,823 - 43,519,693 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1043,509,826 - 43,520,086 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1048,211,194 - 48,221,128 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01047,701,535 - 47,711,473 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01043,205,147 - 43,215,084 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01044,736,547 - 44,746,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1044,736,545 - 44,746,549 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01044,496,852 - 44,507,131 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,022,261 - 45,032,123 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1042,790,103 - 42,796,815 (-)NCBICelera
Cytogenetic Map10q22NCBI
Cfap144
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541829,605,614 - 29,609,806 (+)NCBIChiLan1.0ChiLan1.0
CFAP144
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21183,656,272 - 183,665,077 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11182,797,909 - 182,806,721 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,446,359 - 42,455,170 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1143,823,403 - 43,832,236 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl143,820,716 - 43,832,236 (+)Ensemblpanpan1.1panPan2
CFAP144
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,990,826 - 17,000,220 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1517,118,357 - 17,127,841 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01517,172,876 - 17,181,347 (-)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.01517,019,465 - 17,028,975 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,093,122 - 17,102,598 (-)NCBIUU_Cfam_GSD_1.0
CFAP144
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6168,060,631 - 168,072,904 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16168,062,511 - 168,072,900 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26155,499,125 - 155,509,464 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CFAP144
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12089,641,849 - 89,650,587 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2089,641,849 - 89,650,417 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603327,267,887 - 27,276,623 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cfap144
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247431,224,945 - 1,229,180 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247431,224,914 - 1,229,474 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cfap144
31 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:247
Count of miRNA genes:129
Interacting mature miRNAs:133
Transcripts:ENSMUST00000060581, ENSMUST00000094156
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5406567063319522Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
13513917Heal54_mwound healing/ regeneration 54 (mouse)115787291759879610Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000060581   ⟹   ENSMUSP00000051960
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,683,637 - 58,692,786 (-)Ensembl
GRCm38.p6 Ensembl1158,792,811 - 58,801,960 (-)Ensembl
RefSeq Acc Id: ENSMUST00000094156   ⟹   ENSMUSP00000091708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,683,623 - 58,692,786 (-)Ensembl
GRCm38.p6 Ensembl1158,792,797 - 58,801,960 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238886   ⟹   ENSMUSP00000159184
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,683,629 - 58,692,786 (-)Ensembl
GRCm38.p6 Ensembl1158,792,803 - 58,801,960 (-)Ensembl
RefSeq Acc Id: ENSMUST00000239007   ⟹   ENSMUSP00000159142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,683,629 - 58,692,786 (-)Ensembl
GRCm38.p6 Ensembl1158,792,803 - 58,801,960 (-)Ensembl
RefSeq Acc Id: NM_001162878   ⟹   NP_001156350
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,683,628 - 58,692,786 (-)NCBI
GRCm381158,792,802 - 58,801,960 (-)NCBI
MGSCv371158,606,304 - 58,615,462 (-)RGD
Celera1163,555,369 - 63,564,441 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_029283   ⟹   NP_083559
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,683,628 - 58,692,786 (-)NCBI
GRCm381158,792,802 - 58,801,960 (-)NCBI
MGSCv371158,606,304 - 58,615,462 (-)RGD
Celera1163,555,369 - 63,564,441 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_083559   ⟸   NM_029283
- Peptide Label: isoform 1
- UniProtKB: Q5NC57 (UniProtKB/Swiss-Prot),   Q3TZB7 (UniProtKB/Swiss-Prot),   Q9CXW5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001156350   ⟸   NM_001162878
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSMUSP00000159142   ⟸   ENSMUST00000239007
RefSeq Acc Id: ENSMUSP00000159184   ⟸   ENSMUST00000238886
RefSeq Acc Id: ENSMUSP00000091708   ⟸   ENSMUST00000094156
RefSeq Acc Id: ENSMUSP00000051960   ⟸   ENSMUST00000060581

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5NC57-F1-model_v2 AlphaFold Q5NC57 1-135 view protein structure

Promoters
RGD ID:8674766
Promoter ID:EPDNEW_M15413
Type:initiation region
Name:Fam183b_1
Description:Mus musculus family with sequence similarity 183, member B ,transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381158,801,927 - 58,801,987EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922679 AgrOrtholog
Ensembl Genes ENSMUSG00000049154 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000060581 ENTREZGENE
  ENSMUST00000060581.5 UniProtKB/Swiss-Prot
  ENSMUST00000094156 ENTREZGENE
  ENSMUST00000094156.12 UniProtKB/Swiss-Prot
  ENSMUST00000238886.2 UniProtKB/TrEMBL
  ENSMUST00000239007.2 UniProtKB/TrEMBL
InterPro FAM183 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75429 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1922679 ENTREZGENE
NCBI Gene 75429 ENTREZGENE
PANTHER PROTEIN FAM183B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR33865 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FAM183 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cfap144 PhenoGen
UniProt A0A0R4J0N6_MOUSE UniProtKB/TrEMBL
  D2D553_MOUSE UniProtKB/TrEMBL
  F183B_MOUSE UniProtKB/Swiss-Prot
  Q3TZB7 ENTREZGENE
  Q5NC57 ENTREZGENE
  Q9CXW5 ENTREZGENE
UniProt Secondary Q3TZB7 UniProtKB/Swiss-Prot
  Q9CXW5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-30 Cfap144  cilia and flagella associated protein 144  Fam183b  family with sequence similarity 183, member B  Symbol and/or name updated 27372883 PROVISIONAL