Stpg4 (sperm tail PG rich repeat containing 4) - Rat Genome Database

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Gene: Stpg4 (sperm tail PG rich repeat containing 4) Mus musculus
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Symbol: Stpg4
Name: sperm tail PG rich repeat containing 4
RGD ID: 1623906
MGI Page MGI
Description: Enables chromatin binding activity and histone binding activity. Involved in DNA demethylation of male pronucleus and positive regulation of DNA demethylation. Acts upstream of or within C-5 methylation of cytosine. Located in cytoplasm; germinal vesicle; and pronucleus. Orthologous to human STPG4 (sperm-tail PG-rich repeat containing 4); INTERACTS WITH benzo[a]pyrene; triptonide; (+)-catechin (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700011E24Rik; GSE; hypothetical protein LOC75467; RIKEN cDNA 1700011E24 gene; sperm-tail PG-rich repeat-containing protein 4; uncharacterized protein C2orf61 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391787,696,998 - 87,735,526 (-)NCBIGRCm39mm39
GRCm39 Ensembl1787,696,999 - 87,735,169 (-)Ensembl
GRCm381787,389,570 - 87,428,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1787,389,571 - 87,427,741 (-)EnsemblGRCm38mm10GRCm38
MGSCv371787,788,911 - 87,827,081 (-)NCBIGRCm37mm9NCBIm37
MGSCv361787,297,897 - 87,336,067 (-)NCBImm8
Celera1791,786,747 - 91,825,778 (-)NCBICelera
Cytogenetic Map17E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IDA)
female pronucleus  (IBA,IDA)
germinal vesicle  (IBA,IDA)
male pronucleus  (IBA,IDA)
nucleus  (IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14610273   PMID:16141072   PMID:16141073   PMID:16571911   PMID:21677750   PMID:21873635   PMID:23560077  
PMID:27357688   PMID:28930672  


Genomics

Comparative Map Data
Stpg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391787,696,998 - 87,735,526 (-)NCBIGRCm39mm39
GRCm39 Ensembl1787,696,999 - 87,735,169 (-)Ensembl
GRCm381787,389,570 - 87,428,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1787,389,571 - 87,427,741 (-)EnsemblGRCm38mm10GRCm38
MGSCv371787,788,911 - 87,827,081 (-)NCBIGRCm37mm9NCBIm37
MGSCv361787,297,897 - 87,336,067 (-)NCBImm8
Celera1791,786,747 - 91,825,778 (-)NCBICelera
Cytogenetic Map17E4NCBI
STPG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl247,045,538 - 47,155,308 (-)EnsemblGRCh38hg38GRCh38
GRCh38247,086,991 - 47,155,308 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37247,314,130 - 47,382,447 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36247,209,091 - 47,235,930 (-)NCBINCBI36hg18NCBI36
Celera247,152,977 - 47,221,350 (-)NCBI
Cytogenetic Map2p21NCBI
HuRef247,051,202 - 47,119,655 (-)NCBIHuRef
CHM1_1247,244,382 - 47,312,761 (-)NCBICHM1_1
Stpg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.267,108,827 - 7,158,519 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl67,108,869 - 7,151,390 (+)Ensembl
Rnor_6.0611,014,596 - 11,063,509 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl611,022,034 - 11,063,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0621,002,682 - 21,051,287 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4610,902,817 - 10,947,732 (-)NCBIRGSC3.4rn4RGSC3.4
Celera66,860,173 - 6,901,319 (+)NCBICelera
Cytogenetic Map6q12NCBI
Stpg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544113,925,403 - 13,969,052 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544113,926,926 - 13,969,316 (-)NCBIChiLan1.0ChiLan1.0
STPG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A48,131,530 - 48,199,723 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A48,131,547 - 48,199,596 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A47,201,536 - 47,271,253 (-)NCBIMhudiblu_PPA_v0panPan3
STPG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11049,255,715 - 49,294,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1049,255,723 - 49,294,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1049,109,366 - 49,147,983 (-)NCBI
ROS_Cfam_1.01050,126,166 - 50,164,993 (-)NCBI
UMICH_Zoey_3.11049,834,129 - 49,872,690 (-)NCBI
UNSW_CanFamBas_1.01050,123,664 - 50,162,186 (-)NCBI
UU_Cfam_GSD_1.01050,307,790 - 50,346,314 (-)NCBI
Stpg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629233,797,317 - 33,838,489 (+)NCBI
SpeTri2.0NW_0049365085,229,734 - 5,267,094 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STPG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl393,372,045 - 93,438,068 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1393,386,523 - 93,438,070 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2399,516,465 - 99,563,978 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STPG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11460,046,418 - 60,150,224 (+)NCBI
ChlSab1.1 Ensembl1460,047,449 - 60,104,570 (+)Ensembl
Vero_WHO_p1.0NW_02366604551,741,463 - 51,800,004 (-)NCBI
Stpg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473828,481,864 - 28,525,079 (-)NCBI

Position Markers
D17Mit130  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381787,393,770 - 87,393,999UniSTSGRCm38
MGSCv371787,793,110 - 87,793,339UniSTSGRCm37
Celera1791,790,946 - 91,791,175UniSTS
Cytogenetic Map17E4UniSTS
cM Map1755.7UniSTS
Whitehead Genetic1749.2UniSTS
Whitehead/MRC_RH171084.27UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175680065690800808Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175680065690800808Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175680065690800808Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175680065690800808Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175680065690800808Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175680065690800808Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175722744793199751Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5728209491282202Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176199358194987271Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176199358194987271Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176357811994987271Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176490750994987271Mouse
14928308Manh82_mmandible shape 82 (mouse)176600781494987271Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176863389194987271Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177039377094987271Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177039377094987271Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177039377094987271Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177039377094987271Mouse
1357528Nhdlq3_mnon-HDL QTL 3 (mouse)Not determined177308770494987271Mouse
4141195Nilac11_mnicotine induced locomotor activity 11 (mouse)Not determined177308770494987271Mouse
4141697Hbnr3_mHeligmosomoides bakeri nematode resistance 3 (mouse)Not determined7380065693199751Mouse
1357552Aaj4_manxiety in A/J 4 (mouse)Not determined177428209490087842Mouse
1357646Axtq3_manxiety QTL 3 (mouse)Not determined177428209490087842Mouse
14697708Stsl5_mSalmonella typhimurium susceptibility locus 5 (mouse)178050000091100000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:90
Interacting mature miRNAs:93
Transcripts:ENSMUST00000040609
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000040609   ⟹   ENSMUSP00000044250
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,696,999 - 87,735,169 (-)Ensembl
GRCm38.p6 Ensembl1787,389,571 - 87,427,741 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186211   ⟹   ENSMUSP00000140203
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,718,633 - 87,735,136 (-)Ensembl
GRCm38.p6 Ensembl1787,411,205 - 87,427,708 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187078   ⟹   ENSMUSP00000140579
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,697,004 - 87,735,115 (-)Ensembl
GRCm38.p6 Ensembl1787,389,576 - 87,427,687 (-)Ensembl
RefSeq Acc Id: ENSMUST00000189157
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,724,918 - 87,735,063 (-)Ensembl
GRCm38.p6 Ensembl1787,417,490 - 87,427,635 (-)Ensembl
RefSeq Acc Id: ENSMUST00000189487
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,724,928 - 87,735,063 (-)Ensembl
GRCm38.p6 Ensembl1787,417,500 - 87,427,635 (-)Ensembl
RefSeq Acc Id: NM_029298   ⟹   NP_083574
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,696,999 - 87,735,169 (-)NCBI
GRCm381787,389,571 - 87,427,741 (-)NCBI
MGSCv371787,788,911 - 87,827,081 (-)RGD
Celera1791,786,747 - 91,825,778 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006525070   ⟹   XP_006525133
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,703,145 - 87,735,526 (-)NCBI
GRCm381787,397,635 - 87,428,081 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006525071   ⟹   XP_006525134
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,701,015 - 87,735,493 (-)NCBI
GRCm381787,393,587 - 87,428,051 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006525072   ⟹   XP_006525135
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,696,998 - 87,735,508 (-)NCBI
GRCm381787,389,570 - 87,428,072 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246698   ⟹   XP_011245000
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,718,036 - 87,735,519 (-)NCBI
GRCm381787,410,608 - 87,428,077 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246699   ⟹   XP_011245001
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,703,154 - 87,735,500 (-)NCBI
GRCm381787,395,726 - 87,428,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017317707   ⟹   XP_017173196
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,700,705 - 87,735,496 (-)NCBI
GRCm381787,393,277 - 87,428,054 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001782126
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,697,002 - 87,735,496 (-)NCBI
GRCm381787,389,574 - 87,428,054 (-)NCBI
Sequence:
RefSeq Acc Id: XR_385380
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,697,089 - 87,735,495 (-)NCBI
GRCm381787,389,660 - 87,428,054 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_083574   ⟸   NM_029298
- UniProtKB: Q9DAG5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006525135   ⟸   XM_006525072
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006525134   ⟸   XM_006525071
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006525133   ⟸   XM_006525070
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011245001   ⟸   XM_011246699
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_011245000   ⟸   XM_011246698
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017173196   ⟸   XM_017317707
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSMUSP00000140203   ⟸   ENSMUST00000186211
RefSeq Acc Id: ENSMUSP00000044250   ⟸   ENSMUST00000040609
RefSeq Acc Id: ENSMUSP00000140579   ⟸   ENSMUST00000187078

Promoters
RGD ID:13676952
Promoter ID:EPDNEW_M22625
Type:initiation region
Name:Stpg4_1
Description:Mus musculus sperm tail PG rich repeat containing 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381787,427,700 - 87,427,760EPDNEW
RGD ID:6827663
Promoter ID:MM_KWN:24400
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   MEF_B4,   MEF_B6
Transcripts:NM_029298
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361787,826,969 - 87,827,469 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922717 AgrOrtholog
Ensembl Genes ENSMUSG00000036557 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000044250 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000140203 UniProtKB/TrEMBL
  ENSMUSP00000140579 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000040609 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000186211 UniProtKB/TrEMBL
  ENSMUST00000187078 UniProtKB/TrEMBL
InterPro SHIPPO-rpt UniProtKB/Swiss-Prot
  STPG4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75467 UniProtKB/Swiss-Prot
MGD MGI:1922717 ENTREZGENE
NCBI Gene 75467 ENTREZGENE
PANTHER PTHR35678 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SHIPPO-rpt UniProtKB/Swiss-Prot
PhenoGen Stpg4 PhenoGen
UniProt A0A087WQI0_MOUSE UniProtKB/TrEMBL
  A0A087WRD7_MOUSE UniProtKB/TrEMBL
  Q9DAG5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-11-01 Stpg4  sperm tail PG rich repeat containing 4  1700011E24Rik  RIKEN cDNA 1700011E24 gene  Symbol and/or name change 5135510 APPROVED