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Gene: H2-Q6 (histocompatibility 2, Q region locus 6) Mus musculus
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Symbol: H2-Q6
Name: histocompatibility 2, Q region locus 6
Description: Predicted to have several functions, including TAP complex binding activity; beta-2-microglobulin binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to localize to several cellular components, including the Golgi medial cisterna; MHC class I protein complex; and endoplasmic reticulum. Is expressed in embryo; placenta; and spleen. Orthologous to human HLA-F (major histocompatibility complex, class I, F); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH benzo[a]pyrene; carbon nanotube; dexamethasone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610037M15Rik; H-2Q6; put. Q8 antigen; Qa-6; Qa6
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381735,424,850 - 35,430,055 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371735,561,822 - 35,565,306 (+)NCBIGRCm37mm9NCBIm37
MGSCv361735,032,930 - 35,036,414 (+)NCBImm8
Cytogenetic Map17 B1NCBI
cM Map1718.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on H2-Q6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1623851
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.