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Gene: Olfr73 (olfactory receptor 73) Mus musculus
Analyze
Symbol:
Olfr73
Name:
olfactory receptor 73
RGD ID:
1623850
MGI Page
MGI
Description:
Exhibits odorant binding activity and olfactory receptor activity. Involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to localize to integral component of plasma membrane. Is expressed in main olfactory bulb and olfactory epithelium. Orthologous to human OR5D18 (olfactory receptor family 5 subfamily D member 18).
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
fascin-1; GA_x6K02T2Q125-49527073-49526132; mOR-; mOR-EG; MOR174; MOR174-9; olfactory receptor MOR174-9
RGD Orthologs
Alliance Genes
More Info
more info ...
More Info
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 2 87,864,540 - 87,865,481 (-) NCBI GRCm39 mm39 GRCm38 2 88,034,196 - 88,035,137 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 2 88,032,288 - 88,037,699 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 2 87,874,353 - 87,875,294 (-) NCBI GRCm37 mm9 NCBIm37 MGSCv36 2 87,835,035 - 87,835,976 (-) NCBI mm8 Celera 2 89,630,838 - 89,631,779 (-) NCBI Celera Cytogenetic Map 2 D NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
(+)-nootkatone multiple interactions EXP 6480464 nootkatone binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of OLFR73 mRNA CTD PMID:21354282 , PMID:25270620 3',5'-cyclic AMP multiple interactions EXP 6480464 [[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA more ... CTD PMID:12767924 , PMID:15716417 benzo[a]pyrene increases expression ISO RGD:1345975 6480464 Benzoapyrene results in increased expression of OR5D18 mRNA CTD PMID:22316170 benzo[a]pyrene decreases methylation ISO RGD:1345975 6480464 Benzoapyrene results in decreased methylation of OR5D18 promoter CTD PMID:27901495 calcium atom multiple interactions EXP 6480464 [ethyl vanillin binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium more ... CTD PMID:14685265 , PMID:15716417 calcium(0) multiple interactions EXP 6480464 [ethyl vanillin binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium more ... CTD PMID:14685265 , PMID:15716417 cyclohexanones multiple interactions EXP 6480464 Cyclohexanones binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 ethyl vanillin multiple interactions EXP 6480464 [ethyl vanillin binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium, ethyl vanillin binds to and results in increased activity of OLFR73 protein CTD PMID:15716417 eugenol multiple interactions EXP 6480464 [[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA more ... CTD PMID:12767924 more ... eugenol increases activity EXP 6480464 Eugenol results in increased activity of OLFR73 protein CTD PMID:12767924 eugenol affects binding EXP 6480464 Eugenol binds to OLFR73 protein CTD PMID:14685265 isoeugenol multiple interactions EXP 6480464 isoeugenol binds to and results in decreased activity of OLFR73 protein, isoeugenol binds to and results in increased activity of OLFR73 protein CTD PMID:15574817 , PMID:21142015 isomethyleugenol multiple interactions EXP 6480464 [isomethyleugenol binds to and results in decreased activity of OLFR73 protein] which results in decreased transport of Calcium more ... CTD PMID:14685265 more ... methylparaben increases expression ISO RGD:1345975 6480464 methylparaben results in increased expression of OR5D18 mRNA CTD PMID:17121429 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of OLFR73 mRNA CTD PMID:17562736 raspberry ketone multiple interactions EXP 6480464 raspberry ketone binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 trans-isoeugenol multiple interactions EXP 6480464 isoeugenol binds to and results in decreased activity of OLFR73 protein, isoeugenol binds to and results in increased activity of OLFR73 protein CTD PMID:15574817 , PMID:21142015 valproic acid decreases methylation ISO RGD:1345975 6480464 Valproic Acid results in decreased methylation of OR5D18 gene CTD PMID:29154799 vanillic acid multiple interactions EXP 6480464 Vanillic Acid analog binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 vanillyl alcohol multiple interactions EXP 6480464 vanillyl alcohol binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 zingerone multiple interactions EXP 6480464 zingerone binds to and results in increased activity of OLFR73 protein CTD PMID:21142015
Biological Process
G protein-coupled receptor signaling pathway IBA PANTHER:PTN001571548 2290270 MGI:6201960 , PMID:21873635 GO_Central MGI:6201960 , PMID:21873635 G protein-coupled receptor signaling pathway ISA protein_id:BAB59037 2290270 MGI:3029684 , PMID:14611657 MGI MGI:3029684 , PMID:14611657 G protein-coupled receptor signaling pathway IDA 2290270 MGI:2148342 , PMID:11487625 MGI MGI:2148342 , PMID:11487625 sensory perception of smell ISA protein_id:BAB59037 2290270 MGI:3029684 , PMID:14611657 MGI MGI:3029684 , PMID:14611657 sensory perception of smell IBA PANTHER:PTN001571548 2290270 MGI:6201960 , PMID:21873635 GO_Central MGI:6201960 , PMID:21873635 sensory perception of smell IDA 2290270 MGI:2148342 , PMID:11487625 MGI MGI:2148342 , PMID:11487625
Molecular Function
odorant binding IBA PANTHER:PTN001571548 2290270 MGI:6201960 , PMID:21873635 GO_Central MGI:6201960 , PMID:21873635 odorant binding IDA 2290270 MGI:2148342 , PMID:11487625 MGI MGI:2148342 , PMID:11487625 olfactory receptor activity IDA 2290270 MGI:2148342 , PMID:11487625 MGI MGI:2148342 , PMID:11487625 olfactory receptor activity IBA PANTHER:PTN001571548 2290270 MGI:6201960 , PMID:21873635 GO_Central MGI:6201960 , PMID:21873635 olfactory receptor activity ISA protein_id:BAB59037 2290270 MGI:3029684 , PMID:14611657 MGI MGI:3029684 , PMID:14611657
References
Additional References at PubMed
Genomics
QTLs in Region (GRCm38)
4142088 Parms1_m patched associated RMS 1 (mouse) Not determined 74693773 114293051 Mouse 10044002 Hdl7_m HDL level 7 (mouse) Not determined 2 63175610 97175769 Mouse 1301374 Cplaq7_m circadian period of locomotor activity 7 (mouse) Not determined 2 76591138 110591306 Mouse 1301344 Lith1_m lithogenic gene 1 (mouse) Not determined 2 45457623 145470727 Mouse 4141236 Hbnr5_m Heligmosomoides bakeri nematode resistance 5 (mouse) Not determined 31324555 105313225 Mouse 13463482 Mchq17_m mean corpuscular hemoglobin QTL 17 (mouse) 2 67817543 101817798 Mouse 1301948 Elsgp3_m elevated serum gp70 3 (mouse) Not determined 2 68893925 102894063 Mouse 11038697 Ltpr2d_m Leishmania tropica response 2d (mouse) 2 86265371 120265478 Mouse 1301834 Bits1_m bitterness sensitivity 1 (mouse) Not determined 2 87610298 121610433 Mouse 1357454 Kidq1_m kidney weight QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 1357881 Estoq1_m embryo survival total QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 1357436 Splq1_m spleen weight QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 1558899 Egq1_m early growth QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 4142299 Pbwg1.4_m postnatal body weight growth 1.4 (mouse) Not determined 55624072 89624172 Mouse 1558901 Skmw8_m skeletal muscle weight 8 (mouse) Not determined 2 84178143 118178248 Mouse 11038698 Ltpr2c_m Leishmania tropica response 2c (mouse) 2 86265371 120265478 Mouse 1300852 Lmr14_m leishmaniasis resistance 14 (mouse) Not determined 2 86265371 120265478 Mouse 1301769 Orgwq2_m organ weight QTL 2 (mouse) Not determined 2 3886089 93591306 Mouse 13824983 Vclq1_m curvilinear velocity QTL 1 (mouse) 2 62000000 137000000 Mouse 1301897 Scc2_m colon tumor susceptibility 2 (mouse) Not determined 2 85893925 90580647 Mouse 11049565 Lmr28g_m leishmaniasis resistance 28g (mouse) 2 86265371 120265478 Mouse 1301109 Dntcs2_m dental caries susceptibility 2 (mouse) Not determined 2 40995481 115079684 Mouse 10412082 Hylaq1_m Hyperlocomotor activity related QTL 1 (mouse) Not determined 2 84182854 148825550 Mouse 1301405 Etohr_m ethanol response acute (mouse) Not determined 2 63175610 97175769 Mouse 1357577 Trmq3_m T cell ratio modifier QTL 3 (mouse) Not determined 2 60690268 119525037 Mouse 5491196 Mobq6_m multigenic obesity QTL 6 (mouse) Not determined 2 85893925 181254801 Mouse 1357829 Lvrq1_m liver weight QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 1301882 Etohc2_m ethanol consumption 2 (mouse) Not determined 2 68893925 102894063 Mouse 5491197 Mobq5_m multigenic obesity QTL 5 (mouse) Not determined 2 65439402 162677006 Mouse 1357681 Hrtq1_m heart weight QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 1302174 Dssc2_m dextran sodium sulfate induced colitis QTL2 (mouse) Not determined 2 24334620 148858457 Mouse 1558966 W10q9_m weight 10 weeks QTL 9 (mouse) Not determined 2 20892967 119064359 Mouse 10053681 Lith24_m lithogenic gene 24 (mouse) Not determined 2 63175610 97175769 Mouse 4141854 T2dm2sa_m type 2 diabetes mellitus 2 in SMXA RI mice (mouse) Not determined 2 29417935 148533014 Mouse 10043894 Bw22_m body weight QTL 22 (mouse) Not determined 2 81064989 115064989 Mouse 1558915 W3q1_m weight 3 weeks QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 12738429 Lfibq18_m liver fibrosis QTL 18 (mouse) 2 58089647 92089647 Mouse 4141155 Plast2b_m plasma plant sterol 2b (mouse) Not determined 2 84182854 148680255 Mouse 1301660 Iba1_m induction of brown adipocytes 1 (mouse) Not determined 2 67817543 101817798 Mouse 1301048 Actre2_m activity response to ethanol 2 (mouse) Not determined 2 63175610 97175769 Mouse 1301873 Hsl1_m hyperoxia susceptibility locus 1 (mouse) Not determined 2 63739810 97739957 Mouse 1301703 Bomd3_m bone mineral density 3 (mouse) Not determined 2 63175610 97175769 Mouse 1300662 Etohila_m ethanol induced locomotor activity (mouse) Not determined 2 63175610 97175769 Mouse 39128209 Lwq14_m liver weight QTL 14 (mouse) 2 20892967 119064359 Mouse 1558738 W6q1_m weight 6 weeks QTL 1 (mouse) Not determined 2 20892967 119064359 Mouse 4141406 Alpq2_m alcohol preference QTL 2 (mouse) Not determined 2 57693773 91693944 Mouse 11528549 Sluc31_m susceptibility to lung cancer 31 (mouse) 2 74693773 129371085 Mouse 4141657 Mohg1_m modifier of hg 1 (mouse) Not determined 2 76848414 103265478 Mouse