Trim30d (tripartite motif-containing 30D) - Rat Genome Database

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Gene: Trim30d (tripartite motif-containing 30D) Mus musculus
Analyze
No known orthologs.
Symbol: Trim30d
Name: tripartite motif-containing 30D
RGD ID: 1623833
MGI Page MGI
Description: Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; protein K63-linked ubiquitination; and regulation of signal transduction. Predicted to be located in P-body. Predicted to be active in cytosol and nucleoplasm. Predicted to colocalize with omegasome. Orthologous to human TRIM5 (tripartite motif containing 5); INTERACTS WITH 1,2-dichloroethane; benzo[a]pyrene; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI451617; hypothetical protein LOC209387; Trim; TRIM30; TRIM30-3; Trim79; tripartite motif protein 30-like; tripartite motif-containing 79
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397104,119,221 - 104,157,062 (-)NCBIGRCm39mm39
GRCm39 Ensembl7104,119,221 - 104,157,056 (-)Ensembl
GRCm387104,470,014 - 104,507,853 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7104,470,014 - 104,507,849 (-)EnsemblGRCm38mm10GRCm38
MGSCv377111,618,528 - 111,656,363 (-)NCBIGRCm37mm9NCBIm37
MGSCv367104,345,665 - 104,381,646 (-)NCBImm8
Celera7104,768,247 - 104,801,941 (-)NCBICelera
Cytogenetic Map7E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (IBA)
nucleoplasm  (IBA)
omegasome  (ISO)
P-body  (ISO)

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:19147168   PMID:21267068   PMID:21677750   PMID:21873635  
PMID:21925107  


Genomics

Position Markers
AI451617  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7E3UniSTS
Whitehead/MRC_RH71050.13UniSTS
UniSTS:234144  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387104,500,535 - 104,500,629UniSTSGRCm38
GRCm38164,724,067 - 64,724,161UniSTSGRCm38
MGSCv37164,770,641 - 64,770,735UniSTSGRCm37
MGSCv377111,649,049 - 111,649,143UniSTSGRCm37
Celera165,225,723 - 65,225,817UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map7E3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730500000109400000Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736580590116817642Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745512542119094307Mouse
13208555Lgth10_mbody length 10 (mouse)752000000126000000Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)755169841117223580Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)757300000134400000Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)762100000121800000Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)762100000124100000Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765600000126900000Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)768200000105800000Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)768200000119900000Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)768200000124600000Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)768200000125400000Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)770300000120900000Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770493929104494171Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772614164106614164Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773400000126100000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)774076757108076757Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)775200000122600000Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)775200000122600000Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775745007109745138Mouse
14746989Manh62_mmandible shape 62 (mouse)776093321110093321Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)779000000137300000Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80902474114902584Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780902474114902584Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)781200000127100000Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781600000124600000Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781800000126900000Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)782200000126900000Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785400000124600000Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785716387112934612Mouse
1301647Elpt_melevated leptin (mouse)Not determined786850979120851122Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787394725121394859Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787394725121394859Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787394725121394859Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787493929119886157Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787600000126900000Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787600000126900000Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)788200000108500000Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791883789125883949Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791883789125883949Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793792641127792834Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798565687132565775Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798795739132795739Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined7100238481134238481Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7101151499135151620Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7101394038135394119Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7102094158136094307Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7102094158136094307Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7102094158136094307Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102885996136886157Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:644
Count of miRNA genes:450
Interacting mature miRNAs:499
Transcripts:ENSMUST00000033211, ENSMUST00000071069, ENSMUST00000141063
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000033211   ⟹   ENSMUSP00000033211
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7104,121,051 - 104,157,032 (-)Ensembl
GRCm38.p6 Ensembl7104,471,844 - 104,507,825 (-)Ensembl
RefSeq Acc Id: ENSMUST00000071069   ⟹   ENSMUSP00000065020
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7104,119,221 - 104,157,056 (-)Ensembl
GRCm38.p6 Ensembl7104,470,014 - 104,507,849 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141063   ⟹   ENSMUSP00000115684
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7104,121,430 - 104,132,633 (-)Ensembl
GRCm38.p6 Ensembl7104,472,223 - 104,483,426 (-)Ensembl
RefSeq Acc Id: NM_001167828   ⟹   NP_001161300
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397104,119,221 - 104,157,056 (-)NCBI
GRCm387104,470,014 - 104,507,849 (-)ENTREZGENE
MGSCv377111,618,528 - 111,656,363 (-)RGD
Celera7104,768,247 - 104,801,941 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_199146   ⟹   NP_954597
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397104,119,221 - 104,157,056 (-)NCBI
GRCm387104,470,014 - 104,507,849 (-)ENTREZGENE
MGSCv377111,618,528 - 111,656,363 (-)RGD
Celera7104,768,247 - 104,801,941 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006507546   ⟹   XP_006507609
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397104,121,770 - 104,157,062 (-)NCBI
GRCm387104,472,563 - 104,507,853 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006507547   ⟹   XP_006507610
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397104,122,025 - 104,157,062 (-)NCBI
GRCm387104,472,818 - 104,507,853 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006507548   ⟹   XP_006507611
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397104,119,221 - 104,157,062 (-)NCBI
GRCm387104,470,014 - 104,507,853 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006507549   ⟹   XP_006507612
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397104,122,025 - 104,157,062 (-)NCBI
GRCm387104,472,818 - 104,507,853 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_954597   ⟸   NM_199146
- Peptide Label: isoform 1
- UniProtKB: E9PWL0 (UniProtKB/TrEMBL),   Q3TNW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001161300   ⟸   NM_001167828
- Peptide Label: isoform 2
- UniProtKB: Q3TNW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006507609   ⟸   XM_006507546
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006507611   ⟸   XM_006507548
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006507612   ⟸   XM_006507549
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006507610   ⟸   XM_006507547
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000065020   ⟸   ENSMUST00000071069
RefSeq Acc Id: ENSMUSP00000033211   ⟸   ENSMUST00000033211
RefSeq Acc Id: ENSMUSP00000115684   ⟸   ENSMUST00000141063
Protein Domains
B box-type   B30.2/SPRY   RING-type

Promoters
RGD ID:8665087
Promoter ID:EPDNEW_M10575
Type:multiple initiation site
Name:Trim30d_1
Description:Mus musculus tripartite motif-containing 30D , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387104,507,850 - 104,507,910EPDNEW
RGD ID:6840512
Promoter ID:MM_KWN:52018
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:NM_199146,   OTTMUST00000046007
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367111,656,106 - 111,656,606 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3035181 AgrOrtholog
Ensembl Genes ENSMUSG00000057596 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000033211 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000065020 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000115684 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033211 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000071069 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000141063 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  SPRY_rcpt UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report mmu:209387 UniProtKB/TrEMBL
MGD MGI:3035181 ENTREZGENE
NCBI Gene 209387 ENTREZGENE
Pfam SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PhenoGen Trim30d PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
UniProt E9PWL0 ENTREZGENE, UniProtKB/TrEMBL
  F6SX36_MOUSE UniProtKB/TrEMBL
  Q3TNW3 ENTREZGENE, UniProtKB/TrEMBL
  Q6PHA8_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Trim30d  tripartite motif-containing 30D  AI451617  expressed sequence AI451617  Symbol and/or name change 5135510 APPROVED