Il20rb (interleukin 20 receptor beta) - Rat Genome Database
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Gene: Il20rb (interleukin 20 receptor beta) Mus musculus
Analyze
Symbol: Il20rb
Name: interleukin 20 receptor beta
RGD ID: 1623828
MGI Page MGI
Description: Exhibits interleukin-20 binding activity. Involved in several processes, including negative regulation of T cell proliferation; negative regulation of type IV hypersensitivity; and regulation of cytokine production. Predicted to localize to integral component of membrane and plasma membrane. Orthologous to human IL20RB (interleukin 20 receptor subunit beta); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AV228068; fibronectin type III domain containing 6; Fndc; Fndc6; Gm186; Il2; Il20R2; interleukin-20 receptor subunit beta; MGC130209
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399100,339,772 - 100,368,526 (-)NCBIGRCm39mm39
GRCm389100,457,719 - 100,486,473 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9100,457,719 - 100,486,788 (-)EnsemblGRCm38mm10GRCm38
MGSCv379100,358,138 - 100,386,892 (-)NCBIGRCm37mm9NCBIm37
MGSCv369100,267,073 - 100,295,737 (-)NCBImm8
Celera999,996,528 - 100,025,243 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466305   PMID:12466851   PMID:12477932   PMID:12819125   PMID:16141072   PMID:16141073   PMID:17069926   PMID:17074928  
PMID:18264109   PMID:18799693   PMID:19124723   PMID:21267068   PMID:21282332   PMID:21677750   PMID:21844205   PMID:21873635   PMID:23793061   PMID:23811545   PMID:27009487   PMID:31252033  


Genomics

Comparative Map Data
Il20rb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399100,339,772 - 100,368,526 (-)NCBIGRCm39mm39
GRCm389100,457,719 - 100,486,473 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9100,457,719 - 100,486,788 (-)EnsemblGRCm38mm10GRCm38
MGSCv379100,358,138 - 100,386,892 (-)NCBIGRCm37mm9NCBIm37
MGSCv369100,267,073 - 100,295,737 (-)NCBImm8
Celera999,996,528 - 100,025,243 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
IL20RB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3136,946,230 - 137,011,085 (+)EnsemblGRCh38hg38GRCh38
GRCh383136,957,983 - 137,011,085 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373136,676,707 - 136,729,927 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh373136,676,825 - 136,729,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363138,159,397 - 138,212,610 (+)NCBINCBI36hg18NCBI36
Celera3135,102,983 - 135,156,200 (+)NCBI
Cytogenetic Map3q22.3NCBI
HuRef3134,052,492 - 134,105,781 (+)NCBIHuRef
CHM1_13136,640,346 - 136,693,509 (+)NCBICHM1_1
Il20rb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28100,979,085 - 101,010,829 (-)NCBI
Rnor_6.0 Ensembl8108,747,204 - 108,777,717 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08108,745,906 - 108,778,561 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08108,165,070 - 108,194,857 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48105,305,597 - 105,337,224 (-)NCBIRGSC3.4rn4RGSC3.4
Celera8100,377,810 - 100,407,239 (-)NCBICelera
Cytogenetic Map8q31NCBI
Il20rb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555011,826,687 - 1,863,261 (-)NCBIChiLan1.0ChiLan1.0
IL20RB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13141,457,692 - 141,504,744 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3141,474,161 - 141,504,744 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03133,995,863 - 134,045,206 (+)NCBIMhudiblu_PPA_v0panPan3
IL20RB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2333,384,486 - 33,420,016 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12333,384,057 - 33,421,619 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
IL20RB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1377,863,701 - 77,986,156 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11377,946,356 - 77,986,158 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21385,591,946 - 85,626,043 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL20RB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11553,446,410 - 53,493,827 (-)NCBI
ChlSab1.1 Ensembl1553,448,034 - 53,493,618 (-)Ensembl
Il20rb
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473013,371,898 - 13,408,927 (+)NCBI

Position Markers
D9Dcr38  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389100,483,304 - 100,483,399UniSTSGRCm38
MGSCv379100,383,723 - 100,383,818UniSTSGRCm37
Celera9100,022,070 - 100,022,169UniSTS
Cytogenetic Map9E3.3UniSTS
cM Map9 UniSTS
AV228068  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389100,457,845 - 100,457,961UniSTSGRCm38
MGSCv379100,358,264 - 100,358,380UniSTSGRCm37
Celera999,996,654 - 99,996,770UniSTS
Cytogenetic Map9E3.3UniSTS
Whitehead/MRC_RH91015.85UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1309
Count of miRNA genes:604
Interacting mature miRNAs:751
Transcripts:ENSMUST00000098458, ENSMUST00000122880, ENSMUST00000125259, ENSMUST00000136606, ENSMUST00000136856, ENSMUST00000152756
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000098458   ⟹   ENSMUSP00000096057
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9100,457,719 - 100,486,788 (-)Ensembl
RefSeq Acc Id: ENSMUST00000122880
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9100,465,708 - 100,486,385 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125259
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9100,458,530 - 100,461,735 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136606
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9100,457,721 - 100,466,875 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136856
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9100,457,804 - 100,461,763 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152756
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9100,459,077 - 100,470,609 (-)Ensembl
RefSeq Acc Id: NM_001033543   ⟹   NP_001028715
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399100,339,772 - 100,368,526 (-)NCBI
GRCm389100,457,719 - 100,486,473 (-)ENTREZGENE
MGSCv379100,358,138 - 100,386,892 (-)RGD
Celera999,996,528 - 100,025,243 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001028715 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AMR98442 (Get FASTA)   NCBI Sequence Viewer  
  BAE23301 (Get FASTA)   NCBI Sequence Viewer  
  EDL21026 (Get FASTA)   NCBI Sequence Viewer  
  EDL21027 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001028715   ⟸   NM_001033543
- Peptide Label: precursor
- UniProtKB: E9Q9A6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000096057   ⟸   ENSMUST00000098458
Protein Domains
Fibronectin type-III   Interfer-bind

Promoters
RGD ID:6844691
Promoter ID:MM_KWN:58516
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000068020,   OTTMUST00000068022
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369100,361,861 - 100,362,361 (-)MPROMDB
RGD ID:6844690
Promoter ID:MM_KWN:58517
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000098458
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369100,367,021 - 100,367,521 (-)MPROMDB
RGD ID:6844687
Promoter ID:MM_KWN:58519
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000093793,   NM_001033543
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369100,386,671 - 100,387,171 (-)MPROMDB
RGD ID:8670584
Promoter ID:EPDNEW_M13322
Type:multiple initiation site
Name:Il20rb_1
Description:Mus musculus interleukin 20 receptor beta , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389100,486,470 - 100,486,530EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2143266 AgrOrtholog
Ensembl Genes ENSMUSG00000044244 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000096057 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098458 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Interferon_alpha/beta_rcpt_bsu UniProtKB/TrEMBL
KEGG Report mmu:213208 UniProtKB/TrEMBL
MGD MGI:2143266 ENTREZGENE
NCBI Gene 213208 ENTREZGENE
Pfam Interfer-bind UniProtKB/TrEMBL
  Tissue_fac UniProtKB/TrEMBL
PhenoGen Il20rb PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
UniProt A0A142K3A7_MOUSE UniProtKB/TrEMBL
  E9Q9A6 ENTREZGENE, UniProtKB/TrEMBL
  Q3UVG8_MOUSE UniProtKB/TrEMBL