Or2z8 (olfactory receptor family 2 subfamily Z member 8) - Rat Genome Database

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Gene: Or2z8 (olfactory receptor family 2 subfamily Z member 8) Mus musculus
Analyze
No known orthologs.
Symbol: Or2z8
Name: olfactory receptor family 2 subfamily Z member 8
RGD ID: 1623646
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR2Z1 (olfactory receptor family 2 subfamily Z member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MOR282; MOR282-1; olfactory receptor 372; Olfr372
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,811,504 - 72,812,519 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl872,795,062 - 72,814,474 (+)EnsemblGRCm39 Ensembl
GRCm38872,057,660 - 72,058,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl872,041,218 - 72,060,630 (+)EnsemblGRCm38mm10GRCm38
MGSCv37874,581,559 - 74,582,574 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36874,986,671 - 74,987,615 (+)NCBIMGSCv36mm8
Celera876,415,255 - 76,416,270 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14611657   PMID:15081110   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or2z8
28 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:201
Count of miRNA genes:189
Interacting mature miRNAs:198
Transcripts:ENSMUST00000093434
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84474791478748059Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84819016882190288Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85050595884505958Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
11039503Ccc4_mcolitis susceptibility in the Collaborative Cross 4 (mouse)86517423778002730Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86872247983326976Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined871032003105032123Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined871032003105032123Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7158942790929226Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871740461124622354Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71740461124622354Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871829531105829637Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined872122809106123021Mouse

Markers in Region
UniSTS:491979  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38872,057,660 - 72,058,675UniSTSGRCm38
MGSCv37874,581,559 - 74,582,574UniSTSGRCm37
Celera876,415,255 - 76,416,270UniSTS
Cytogenetic Map8B3.3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000093434   ⟹   ENSMUSP00000132724
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl872,811,504 - 72,812,519 (+)Ensembl
GRCm38.p6 Ensembl872,057,660 - 72,058,675 (+)Ensembl
RefSeq Acc Id: ENSMUST00000215324   ⟹   ENSMUSP00000149288
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl872,795,062 - 72,814,474 (+)Ensembl
GRCm38.p6 Ensembl872,041,218 - 72,060,630 (+)Ensembl
RefSeq Acc Id: NM_207555   ⟹   NP_997438
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,811,504 - 72,812,519 (+)NCBI
GRCm38872,057,660 - 72,058,675 (+)ENTREZGENE
MGSCv37874,581,559 - 74,582,574 (+)RGD
Celera876,415,255 - 76,416,270 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_997438 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI50672 (Get FASTA)   NCBI Sequence Viewer  
  AAP70903 (Get FASTA)   NCBI Sequence Viewer  
  EDL10779 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000132724
  ENSMUSP00000132724.2
  ENSMUSP00000149288.2
Reference Protein Sequences
RefSeq Acc Id: NP_997438   ⟸   NM_207555
- UniProtKB: Q7TRY2 (UniProtKB/TrEMBL),   B2RWR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000132724   ⟸   ENSMUST00000093434
RefSeq Acc Id: ENSMUSP00000149288   ⟸   ENSMUST00000215324
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TRY2-F1-model_v2 AlphaFold Q7TRY2 1-314 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030206 AgrOrtholog
Ensembl Genes ENSMUSG00000069998 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000093434 ENTREZGENE
  ENSMUST00000093434.5 UniProtKB/TrEMBL
  ENSMUST00000215324.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:404315 UniProtKB/TrEMBL
MGD MGI:3030206 ENTREZGENE
NCBI Gene 404315 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2z8 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt B2RWR7 ENTREZGENE, UniProtKB/TrEMBL
  Q7TRY2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or2z8  olfactory receptor family 2 subfamily Z member 8  Olfr372  olfactory receptor 372  Symbol and/or name change 5135510 APPROVED