Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of WHAMM mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Whamm (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of WHAMM mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Whamm (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of WHAMM mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of WHAMM mRNA | CTD | PMID:21570461 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of WHAMM mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of WHAMM mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of WHAMM mRNA | CTD | PMID:28628672 | acrylamide | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Acrylamide results in increased expression of WHAMM mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | WHAMM (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of WHAMM gene | CTD | PMID:27153756 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of WHAMM mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Tretinoin results in increased expression of WHAMM mRNA | CTD | PMID:33167477 | aristolochic acid A | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of WHAMM mRNA | CTD | PMID:33212167 | arsane | decreases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Arsenic results in decreased expression of WHAMM mRNA | CTD | PMID:27838757 | arsenic atom | decreases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Arsenic results in decreased expression of WHAMM mRNA | CTD | PMID:27838757 | benzo[a]pyrene | decreases methylation | ISO | WHAMM (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of WHAMM promoter | CTD | PMID:27901495 | bisphenol A | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of WHAMM mRNA | CTD | PMID:28628672 | bisphenol A | decreases methylation | ISO | WHAMM (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of WHAMM gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of WHAMM mRNA | CTD | PMID:33221593 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of WHAMM mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of WHAMM mRNA | CTD | PMID:37325564 | caffeine | increases phosphorylation | ISO | WHAMM (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of WHAMM protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon results in decreased expression of WHAMM mRNA | CTD | PMID:25554681 and PMID:25620056 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of WHAMM mRNA | CTD | PMID:37019170 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of WHAMM gene | CTD | PMID:20938992 | cisplatin | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of WHAMM mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of WHAMM mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | ISO | Whamm (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of WHAMM mRNA | CTD | PMID:24386269 | crocidolite asbestos | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of WHAMM mRNA | CTD | PMID:18687144 | Cuprizon | decreases expression | ISO | Whamm (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of WHAMM mRNA | CTD | PMID:26577399 | cylindrospermopsin | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of WHAMM mRNA | CTD | PMID:24921660 | dexamethasone | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of WHAMM mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of WHAMM mRNA | CTD | PMID:28628672 | dorsomorphin | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WHAMM mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of WHAMM mRNA | CTD | PMID:29803840 | ethyl methanesulfonate | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of WHAMM mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of WHAMM gene | CTD | PMID:20938992 | formaldehyde | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of WHAMM mRNA | CTD | PMID:23649840 | gentamycin | increases expression | ISO | Whamm (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of WHAMM mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of WHAMM mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of WHAMM mRNA | CTD | PMID:28628672 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of WHAMM gene | CTD | PMID:20938992 | lead(0) | affects expression | ISO | WHAMM (Homo sapiens) | 6480464 | Lead affects the expression of WHAMM mRNA | CTD | PMID:28903495 | leflunomide | increases expression | ISO | Whamm (Rattus norvegicus) | 6480464 | leflunomide results in increased expression of WHAMM mRNA | CTD | PMID:24136188 | manganese(II) chloride | decreases expression | ISO | Whamm (Rattus norvegicus) | 6480464 | manganese chloride results in decreased expression of WHAMM mRNA | CTD | PMID:28801915 | methyl methanesulfonate | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of WHAMM mRNA | CTD | PMID:23649840 | nickel atom | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Nickel results in increased expression of WHAMM mRNA | CTD | PMID:23195993 | Nivalenol | increases expression | EXP | | 6480464 | nivalenol results in increased expression of WHAMM mRNA | CTD | PMID:35016910 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of WHAMM mRNA | CTD | PMID:36331819 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of WHAMM mRNA | CTD | PMID:19482888 and PMID:23091169 | phenobarbital | multiple interactions | EXP | | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of WHAMM mRNA] | CTD | PMID:19482888 | phenylmercury acetate | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of WHAMM mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WHAMM mRNA | CTD | PMID:27188386 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of WHAMM mRNA | CTD | PMID:23811191 | SB 431542 | multiple interactions | ISO | WHAMM (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WHAMM mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of WHAMM mRNA | CTD | PMID:32068019 | sunitinib | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Sunitinib results in increased expression of WHAMM mRNA | CTD | PMID:31533062 | tetrachloroethene | decreases expression | EXP | | 6480464 | Tetrachloroethylene results in decreased expression of WHAMM mRNA | CTD | PMID:28973375 | urethane | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Urethane results in increased expression of WHAMM mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | WHAMM (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of WHAMM gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of WHAMM mRNA | CTD | PMID:23179753 | zoledronic acid | increases expression | ISO | WHAMM (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of WHAMM mRNA | CTD | PMID:20977926 | |