Apol11a (apolipoprotein L 11a) - Rat Genome Database

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Gene: Apol11a (apolipoprotein L 11a) Mus musculus
Analyze
Symbol: Apol11a
Name: apolipoprotein L 11a
RGD ID: 1623488
MGI Page MGI
Description: Predicted to enable chloride channel activity and lipid binding activity. Predicted to be located in extracellular space. Predicted to be part of high-density lipoprotein particle and very-low-density lipoprotein particle. Orthologous to human APOL1 (apolipoprotein L1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG626615
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391577,392,329 - 77,402,074 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1577,392,471 - 77,402,251 (+)EnsemblGRCm39 Ensembl
GRCm381577,508,129 - 77,517,874 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1577,508,271 - 77,518,051 (+)EnsemblGRCm38mm10GRCm38
MGSCv371577,338,701 - 77,347,749 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361577,335,526 - 77,344,574 (+)NCBIMGSCv36mm8
Celera1578,991,588 - 79,000,634 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21873635  


Genomics

Comparative Map Data
Apol11a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391577,392,329 - 77,402,074 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1577,392,471 - 77,402,251 (+)EnsemblGRCm39 Ensembl
GRCm381577,508,129 - 77,517,874 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1577,508,271 - 77,518,051 (+)EnsemblGRCm38mm10GRCm38
MGSCv371577,338,701 - 77,347,749 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361577,335,526 - 77,344,574 (+)NCBIMGSCv36mm8
Celera1578,991,588 - 79,000,634 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.4NCBI
Apol11a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,118,668 - 111,142,866 (-)NCBIGRCr8
mRatBN7.27109,248,260 - 109,262,266 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,248,942 - 109,253,716 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07118,835,316 - 118,858,347 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,836,547 - 118,840,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07118,831,067 - 118,853,631 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47115,583,669 - 115,588,293 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17115,617,898 - 115,619,989 (-)NCBI
Celera7105,590,867 - 105,604,871 (-)NCBICelera
Cytogenetic Map7q34NCBI

Variants

.
Variants in Apol11a
361 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:107
Interacting mature miRNAs:113
Transcripts:ENSMUST00000172191
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302002Cocia2_mcocaine induced activation 2 (mouse)Not determined157237245979899178Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
13442492Mecth2_mmechanosensation threshold 2 (mouse)157466284979387201Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000172191   ⟹   ENSMUSP00000132565
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,392,471 - 77,402,251 (+)Ensembl
GRCm38.p6 Ensembl1577,508,271 - 77,518,051 (+)Ensembl
RefSeq Acc Id: NM_001177533   ⟹   NP_001171004
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391577,392,469 - 77,401,519 (+)NCBI
GRCm381577,508,269 - 77,517,319 (+)NCBI
MGSCv371577,338,701 - 77,347,749 (+)RGD
Celera1578,991,588 - 79,000,634 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006521234   ⟹   XP_006521297
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391577,392,329 - 77,402,074 (+)NCBI
GRCm381577,508,129 - 77,517,874 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001171004 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521297 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000132565
  ENSMUSP00000132565.2
Reference Protein Sequences
RefSeq Acc Id: NP_001171004   ⟸   NM_001177533
- UniProtKB: E9PZG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521297   ⟸   XM_006521234
- Peptide Label: isoform X1
- UniProtKB: E9PZG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000132565   ⟸   ENSMUST00000172191

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PZG0-F1-model_v2 AlphaFold E9PZG0 1-334 view protein structure

Promoters
RGD ID:8684204
Promoter ID:EPDNEW_M20133
Type:multiple initiation site
Name:Apol11a_1
Description:Mus musculus apolipoprotein L 11a , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381577,508,271 - 77,508,331EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3649094 AgrOrtholog
Ensembl Genes ENSMUSG00000091650 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000172191 ENTREZGENE
  ENSMUST00000172191.3 UniProtKB/TrEMBL
InterPro ApoL UniProtKB/TrEMBL
KEGG Report mmu:626615 UniProtKB/TrEMBL
MGD MGI:3649094 ENTREZGENE
NCBI Gene 626615 ENTREZGENE
PANTHER ApoL UniProtKB/TrEMBL
  APOLIPOPROTEIN L 10A-RELATED UniProtKB/TrEMBL
Pfam ApoL UniProtKB/TrEMBL
PhenoGen Apol11a PhenoGen
UniProt E9PZG0 ENTREZGENE, UniProtKB/TrEMBL