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Gene: Kptn (kaptin) Mus musculus
Symbol: Kptn
Name: kaptin
Description: Predicted to have actin filament binding activity. Predicted to be involved in cellular response to starvation; negative regulation of TORC1 signaling; and protein localization to lysosome. Predicted to colocalize with filamentous actin. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human KPTN (kaptin, actin binding protein); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310042D10Rik; 2E4; actin-binding protein; C030013F01Rik; KICSTOR complex protein kaptin
Homo sapiens (human) : KPTN (kaptin, actin binding protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kptn (kaptin (actin binding protein))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kptn (kaptin, actin binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : KPTN (kaptin, actin binding protein)
Canis lupus familiaris (dog) : KPTN (kaptin, actin binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kptn (kaptin, actin binding protein)
Sus scrofa (pig) : KPTN (kaptin, actin binding protein)
Chlorocebus sabaeus (African green monkey) : KPTN (kaptin, actin binding protein)
Heterocephalus glaber (naked mole-rat) : Kptn (kaptin, actin binding protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl716,119,895 - 16,127,516 (+)EnsemblGRCm38mm10GRCm38
GRCm38716,119,876 - 16,127,516 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37716,705,225 - 16,712,865 (+)NCBIGRCm37mm9NCBIm37
MGSCv36715,278,430 - 15,286,038 (+)NCBImm8
Celera713,318,462 - 13,326,094 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map78.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kptn
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1623180
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.