Slc41a3 (solute carrier family 41, member 3) - Rat Genome Database
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Gene: Slc41a3 (solute carrier family 41, member 3) Mus musculus
Analyze
Symbol: Slc41a3
Name: solute carrier family 41, member 3
RGD ID: 1623170
MGI Page MGI
Description: Is expressed in alimentary system; eye; hemolymphoid system; liver; and nervous system. Orthologous to human SLC41A3 (solute carrier family 41 member 3); INTERACTS WITH 1,2-dichloroethane; aflatoxin B1; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1010001P06Rik; AI480742; SLC41A; SLC41A1-L2; solute carrier family 41 member 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,579,043 - 90,623,394 (+)NCBIGRCm39mm39
GRCm39 Ensembl690,581,707 - 90,623,394 (+)Ensembl
GRCm38690,604,730 - 90,646,412 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,604,725 - 90,646,412 (+)EnsemblGRCm38mm10GRCm38
MGSCv37690,554,874 - 90,596,406 (+)NCBIGRCm37mm9NCBIm37
MGSCv36690,570,384 - 90,611,916 (+)NCBImm8
Celera692,488,674 - 92,530,325 (+)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11591653   PMID:12466851   PMID:12477932   PMID:14681479   PMID:14691545   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:21267068   PMID:21677750   PMID:21873635   PMID:27349617  


Genomics

Comparative Map Data
Slc41a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,579,043 - 90,623,394 (+)NCBIGRCm39mm39
GRCm39 Ensembl690,581,707 - 90,623,394 (+)Ensembl
GRCm38690,604,730 - 90,646,412 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,604,725 - 90,646,412 (+)EnsemblGRCm38mm10GRCm38
MGSCv37690,554,874 - 90,596,406 (+)NCBIGRCm37mm9NCBIm37
MGSCv36690,570,384 - 90,611,916 (+)NCBImm8
Celera692,488,674 - 92,530,325 (+)NCBICelera
Cytogenetic Map6D1NCBI
SLC41A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3126,006,357 - 126,101,561 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl3126,006,355 - 126,101,561 (-)EnsemblGRCh38hg38GRCh38
GRCh383126,006,357 - 126,101,550 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373125,725,200 - 125,820,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363127,207,890 - 127,285,824 (-)NCBINCBI36hg18NCBI36
Build 343127,207,897 - 127,285,832NCBI
Celera3124,148,794 - 124,244,070 (-)NCBI
Cytogenetic Map3q21.2-q21.3NCBI
HuRef3123,105,704 - 123,200,963 (-)NCBIHuRef
CHM1_13125,687,978 - 125,783,164 (-)NCBICHM1_1
Slc41a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24123,109,555 - 123,154,766 (+)NCBI
Rnor_6.0 Ensembl4123,467,549 - 123,510,217 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04123,467,552 - 123,513,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04187,034,230 - 187,078,591 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4112,051,998 - 112,078,495 (+)NCBICelera
Cytogenetic Map4q34NCBI
Slc41a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542121,349,484 - 21,407,171 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542121,349,484 - 21,407,171 (-)NCBIChiLan1.0ChiLan1.0
SLC41A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13130,388,082 - 130,465,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3130,388,082 - 130,465,689 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03123,069,790 - 123,147,408 (-)NCBIMhudiblu_PPA_v0panPan3
SLC41A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl20115,011 - 211,075 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.120120,589 - 211,554 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC101963026
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936898433,977 - 454,746 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC41A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl753,672,130 - 53,784,882 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1753,672,131 - 53,741,033 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2758,703,341 - 58,726,780 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC41A3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12254,950,899 - 55,030,060 (+)NCBI
ChlSab1.1 Ensembl2254,966,562 - 55,031,564 (+)Ensembl
Slc41a3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624773480,486 - 534,985 (+)NCBI

Position Markers
AI480742  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,646,143 - 90,646,289UniSTSGRCm38
MGSCv37690,596,137 - 90,596,283UniSTSGRCm37
Celera692,530,056 - 92,530,202UniSTS
Cytogenetic Map6D2UniSTS
Whitehead/MRC_RH6924.39UniSTS
Slc41a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D2UniSTS
cM Map6 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:550
Count of miRNA genes:204
Interacting mature miRNAs:231
Transcripts:ENSMUST00000032177, ENSMUST00000044019
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW492407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB849572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB872292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ176613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY108317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN699671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032177   ⟹   ENSMUSP00000032177
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,619,147 - 90,646,412 (+)Ensembl
RefSeq Acc Id: ENSMUST00000044019   ⟹   ENSMUSP00000037473
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,604,725 - 90,646,412 (+)Ensembl
RefSeq Acc Id: NM_001037493   ⟹   NP_001032570
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,596,228 - 90,623,394 (+)NCBI
GRCm38690,619,246 - 90,646,412 (+)NCBI
MGSCv37690,554,874 - 90,596,406 (+)RGD
Celera692,488,674 - 92,530,325 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_027868   ⟹   NP_082144
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,581,862 - 90,623,394 (+)NCBI
GRCm38690,604,880 - 90,646,412 (+)NCBI
MGSCv37690,554,874 - 90,596,406 (+)RGD
Celera692,488,674 - 92,530,325 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506625   ⟹   XP_006506688
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,581,705 - 90,623,394 (+)NCBI
GRCm38690,604,730 - 90,646,412 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006506626   ⟹   XP_006506689
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,595,866 - 90,623,394 (+)NCBI
GRCm38690,618,468 - 90,646,412 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006506627   ⟹   XP_006506690
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,595,469 - 90,623,394 (+)NCBI
GRCm38690,618,468 - 90,646,412 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255596   ⟹   XP_030111456
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,581,714 - 90,623,394 (+)NCBI
GRCm38690,604,742 - 90,646,412 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152308   ⟹   XP_036008201
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,579,043 - 90,623,394 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_082144   ⟸   NM_027868
- Peptide Label: isoform 1
- UniProtKB: Q921R8 (UniProtKB/Swiss-Prot),   G3X937 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001032570   ⟸   NM_001037493
- Peptide Label: isoform 2
- UniProtKB: Q921R8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506688   ⟸   XM_006506625
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006506689   ⟸   XM_006506626
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006506690   ⟸   XM_006506627
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030111456   ⟸   XM_030255596
- Peptide Label: isoform X5
RefSeq Acc Id: ENSMUSP00000032177   ⟸   ENSMUST00000032177
RefSeq Acc Id: ENSMUSP00000037473   ⟸   ENSMUST00000044019
RefSeq Acc Id: XP_036008201   ⟸   XM_036152308
- Peptide Label: isoform X1
Protein Domains
MgtE

Promoters
RGD ID:6839999
Promoter ID:MM_KWN:46890
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000059579
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36690,554,781 - 90,555,281 (+)MPROMDB
RGD ID:6839995
Promoter ID:MM_KWN:46891
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:NM_001037493
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36690,568,861 - 90,569,361 (+)MPROMDB
RGD ID:6890420
Promoter ID:EPDNEW_M8661
Type:initiation region
Name:Slc41a3_1
Description:Mus musculus solute carrier family 41, member 3 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8662  EPDNEW_M8663  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38690,604,923 - 90,604,983EPDNEW
RGD ID:6890422
Promoter ID:EPDNEW_M8662
Type:single initiation site
Name:Slc41a3_3
Description:Mus musculus solute carrier family 41, member 3 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8661  EPDNEW_M8663  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38690,609,941 - 90,610,001EPDNEW
RGD ID:6890424
Promoter ID:EPDNEW_M8663
Type:initiation region
Name:Slc41a3_2
Description:Mus musculus solute carrier family 41, member 3 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8661  EPDNEW_M8662  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38690,619,176 - 90,619,236EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918949 AgrOrtholog
Ensembl Genes ENSMUSG00000030089 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032177 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000037473 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032177 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000044019 ENTREZGENE, UniProtKB/TrEMBL
InterPro SLC41_membr_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLC41_membr_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:71699 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1918949 ENTREZGENE
NCBI Gene 71699 ENTREZGENE
Pfam MgtE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc41a3 PhenoGen
Superfamily-SCOP SSF161093 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3X937 ENTREZGENE, UniProtKB/TrEMBL
  Q921R8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9DC67 UniProtKB/Swiss-Prot